Natasha S Crowcroft
Biographic Data
| ID | 104684 |
|---|---|
| NAME | Natasha S Crowcroft |
| GIVEN NAMES | Natasha S |
| FAMILY NAME | Crowcroft |
| SIGNATURE | CROWCROFT N S |
| AFFILIATIONS | University of Toronto |
| ORCID | 0000-0002-6761-8783 |
| VERIFIED | Yes |
| TOTAL WORKS | 25 |
| TOTAL CITATIONS | 15 |
| AUTHOR COUNT | 25 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1998 |
| LATEST PUBLICATION YEAR | 2024 |
| H-INDEX | 3 |
Global challenges and solutions to achieving and sustaining measles and rubella elimination
Measles and rubella have long been recognized as priorities for disease prevention because of their devastating consequences for child health; hence, all World Health Organization (WHO) regions currently have a goal to eliminate measles and four out of six WHO regions have a goal to eliminate rubella. Significant global progress has been made in the twenty-first century, with more than 40% of countries in the world verified by a Regional Verifica…
Accelerating the Development of Measles and Rubella Microarray Patches to Eliminate Measles and Rubella
Measles and rubella microarray patches (MR-MAPs) are critical in achieving measles and rubella eradication, a goal highly unlikely to meet with current vaccines presentations. With low commercial incentive to MAP developers, limited and uncertain funding, the need for investment in a novel manufacturing facility, and remaining questions about the source of antigen, product demand, and regulatory pathway, MR-MAPs are unlikely to be prequalified by…
Measles Serosurveys
OPINION article Front. Public Health, 15 July 2021Sec. Infectious Diseases – Surveillance, Prevention and Treatment https://doi.org/10.3389/fpubh.2021.539325
Validating viral hepatitis B and C diagnosis codes
Exploring the reasons for low pertussis vaccine effectiveness in Ontario, Canada, 2006–2008
Limitations of administrative data to identify measles cases in Ontario, Canada
How Can We Keep Immigrant Travelers Healthy? Health Challenges Experienced by Canadian South Asian Travelers Visiting Friends and Relatives
Immigrant travelers who visit friends and relatives (VFR travelers) experience substantially higher rates of travel-related infections than other travelers, in part due to low uptake of pretravel health advice. While barriers to accessing advice have been identified, better characterization is needed to inform targeted interventions. We sought to understand how South Asian VFR travelers perceived and responded to travel-related health risks by co…
Evaluation of the ability of standardized supports to improve public health response to syndromic surveillance for respiratory diseases in Canada
This study raises questions about the effectiveness of using standardized protocols to improve the performance of syndromic surveillance in a decentralized public health system. Despite efforts to create standardized protocols and engage public health agencies in the process, no significant differences in the effective use of syndromic alerts were observed beyond year 1. It also raises questions about the minimum capacity of the agency and minimu…
Immunization information systems in Canada
Ethnic disparities in acquiring 2009 pandemic H1N1 influenza
pH1N1 cases were more likely to come from certain ethnic groups compared to test-negative controls. Insights into whether these disparities arise due to social or biological factors are needed in order to understand what approaches can be taken to reduce the burden of a future influenza pandemic
Assessing the Relative Timeliness of Ontario’s Syndromic Surveillance Systems for Early Detection of the 2009 Influenza H1N1 Pandemic Waves
Pandemic H1N1 in Canada and the use of evidence in developing public health policies - A policy analysis
Human papilloma virus vaccination programs reduce health inequity in most scenarios
The global and within-country epidemiology of cervical cancer exemplifies health inequity. Public health programs may reduce absolute risk but increase inequity; inequity may be further compounded by screening programs. In this context, we aimed to explore what the impact of human papillomavirus (HPV) vaccine might have on health equity allowing for uncertainty surrounding the long-term effect of HPV vaccination programs. A simple static multi-wa…
The potential effect of temporary immunity as a result of bias associated with healthy users and social determinants on observations of influenza vaccine effectiveness; could unmeasured confounding ex…
We found that unmeasured healthy user effects and social determinants could result in an apparent association between seasonal influenza vaccine and pandemic influenza infection by virtue of being related to temporary immunity. Adjustment for social determinants of health and the healthy user effects are required in order to improve the quality of observational studies of influenza vaccine effectiveness
The use of syndromic surveillance for decision-making during the H1N1 pandemic
Syndromic surveillance had limited use in decision-making during the 2009 H1N1 pandemic in Ontario. This study provides insights into the reasons why this occurred. Despite this, syndromic data were valued for providing situational awareness and confidence to support public communications and recommendations. Developing an understanding of how syndromic data are utilized during public health events provides valuable evidence to support future inv…
The epidemiology of travel-related Salmonella Enteritidis in Ontario, Canada, 2010–2011
There is a large burden of TR illness from SE in Ontario. Accurate classification of cases by travel history is important to better understand the source of infections. The findings emphasize the need to make travellers, especially to the Caribbean, and health professionals who provide advice to travellers, aware of this risk. The findings may be generalized to other jurisdictions with travel behaviours in their residents similar to Ontario resid…
The Social Determinants of Health and Pandemic H1N1 2009 Influenza Severity
Objectives. We explored the effects of social determinants of health on pandemic H1N1 2009 influenza severity and the role of clinical risk factors in mediating such associations. Methods. We used multivariate logistic regression with generalized estimating equations to examine the associations between individual- and ecological-level social determinants of health and hospitalization for pandemic H1N1 2009 illness in a case-control study in Ontar…
On-time Vaccination Coverage in Premature Infants in Ontario, 2002–2009
Ontario’s School-based HPV Immunization Program
Assessing secondary attack rates among household contacts at the beginning of the influenza A (H1N1) pandemic in Ontario, Canada, April-June 2009
Secondary attack rates for pandemic influenza A (H1N1) were comparable to seasonal influenza estimates suggesting similarities in transmission. High secondary attack rates in children provide additional support for increased susceptibility to infection
Estimating background rates of Guillain-Barré Syndrome in Ontario in order to respond to safety concerns during pandemic H1N1/09 immunization campaign
Our analyses do not suggest an increased number of GBS cases due to the vaccine. Awareness of expected rates of GBS is crucial when assessing adverse events following influenza immunization. Furthermore, since individuals with influenza infection are also at risk of developing GBS, they must be considered in such analyses, particularly if the vaccine campaign and disease are occurring concurrently
Optimizing Canadian Public Immunization Programs
Approaches to Immunization Data Collection Employed Across Canada During the Pandemic (H1N1) 2009 Influenza Vaccination Campaign
Perceptions of immunization information systems for collecting pandemic H1N1 immunization data within Canada's public health community
IISs were perceived as valuable by key informants for strengthening management capacity and improving evaluation of both seasonal and pandemic influenza vaccination campaigns. However, certain implementation restrictions may need to be overcome for these benefits to be achieved
Epidemiology of Epstein-Barr virus infection in pre-adolescent children
STUDY OBJECTIVE: To describe the epidemiology of Epstein-Barr virus (EBV) among primary school children by testing saliva with a new EBV capsid antigen "G" antibody capture radioimmunoassay (GACRIA). DESIGN: A population based sample of 7 year old schoolchildren were followed up at age 11. SETTING: 30 randomly chosen primary schools in Edinburgh, Scotland. PARTICIPANTS: 552 schoolchildren. MEASUREMENTS: Data on risk factors for infection were col…
Pandemic H1N1 in Canada and the use of evidence in developing public health policies - A policy analysis
The Social Determinants of Health and Pandemic H1N1 2009 Influenza Severity
Objectives. We explored the effects of social determinants of health on pandemic H1N1 2009 influenza severity and the role of clinical risk factors in mediating such associations. Methods. We used multivariate logistic regression with generalized estimating equations to examine the associations between individual- and ecological-level social determinants of health and hospitalization for pandemic H1N1 2009 illness in a case-control study in Ontar…
Immunization information systems in Canada
Epidemiology of Epstein-Barr virus infection in pre-adolescent children
STUDY OBJECTIVE: To describe the epidemiology of Epstein-Barr virus (EBV) among primary school children by testing saliva with a new EBV capsid antigen "G" antibody capture radioimmunoassay (GACRIA). DESIGN: A population based sample of 7 year old schoolchildren were followed up at age 11. SETTING: 30 randomly chosen primary schools in Edinburgh, Scotland. PARTICIPANTS: 552 schoolchildren. MEASUREMENTS: Data on risk factors for infection were col…
Perceptions of immunization information systems for collecting pandemic H1N1 immunization data within Canada's public health community
IISs were perceived as valuable by key informants for strengthening management capacity and improving evaluation of both seasonal and pandemic influenza vaccination campaigns. However, certain implementation restrictions may need to be overcome for these benefits to be achieved
Assessing secondary attack rates among household contacts at the beginning of the influenza A (H1N1) pandemic in Ontario, Canada, April-June 2009
Secondary attack rates for pandemic influenza A (H1N1) were comparable to seasonal influenza estimates suggesting similarities in transmission. High secondary attack rates in children provide additional support for increased susceptibility to infection
Estimating background rates of Guillain-Barré Syndrome in Ontario in order to respond to safety concerns during pandemic H1N1/09 immunization campaign
Our analyses do not suggest an increased number of GBS cases due to the vaccine. Awareness of expected rates of GBS is crucial when assessing adverse events following influenza immunization. Furthermore, since individuals with influenza infection are also at risk of developing GBS, they must be considered in such analyses, particularly if the vaccine campaign and disease are occurring concurrently
Optimizing Canadian Public Immunization Programs
Approaches to Immunization Data Collection Employed Across Canada During the Pandemic (H1N1) 2009 Influenza Vaccination Campaign
Human papilloma virus vaccination programs reduce health inequity in most scenarios
The global and within-country epidemiology of cervical cancer exemplifies health inequity. Public health programs may reduce absolute risk but increase inequity; inequity may be further compounded by screening programs. In this context, we aimed to explore what the impact of human papillomavirus (HPV) vaccine might have on health equity allowing for uncertainty surrounding the long-term effect of HPV vaccination programs. A simple static multi-wa…
The potential effect of temporary immunity as a result of bias associated with healthy users and social determinants on observations of influenza vaccine effectiveness; could unmeasured confounding ex…
We found that unmeasured healthy user effects and social determinants could result in an apparent association between seasonal influenza vaccine and pandemic influenza infection by virtue of being related to temporary immunity. Adjustment for social determinants of health and the healthy user effects are required in order to improve the quality of observational studies of influenza vaccine effectiveness
The use of syndromic surveillance for decision-making during the H1N1 pandemic
Syndromic surveillance had limited use in decision-making during the 2009 H1N1 pandemic in Ontario. This study provides insights into the reasons why this occurred. Despite this, syndromic data were valued for providing situational awareness and confidence to support public communications and recommendations. Developing an understanding of how syndromic data are utilized during public health events provides valuable evidence to support future inv…
The epidemiology of travel-related Salmonella Enteritidis in Ontario, Canada, 2010–2011
There is a large burden of TR illness from SE in Ontario. Accurate classification of cases by travel history is important to better understand the source of infections. The findings emphasize the need to make travellers, especially to the Caribbean, and health professionals who provide advice to travellers, aware of this risk. The findings may be generalized to other jurisdictions with travel behaviours in their residents similar to Ontario resid…
The Social Determinants of Health and Pandemic H1N1 2009 Influenza Severity
Objectives. We explored the effects of social determinants of health on pandemic H1N1 2009 influenza severity and the role of clinical risk factors in mediating such associations. Methods. We used multivariate logistic regression with generalized estimating equations to examine the associations between individual- and ecological-level social determinants of health and hospitalization for pandemic H1N1 2009 illness in a case-control study in Ontar…
On-time Vaccination Coverage in Premature Infants in Ontario, 2002–2009
Ontario’s School-based HPV Immunization Program
Assessing the Relative Timeliness of Ontario’s Syndromic Surveillance Systems for Early Detection of the 2009 Influenza H1N1 Pandemic Waves
Pandemic H1N1 in Canada and the use of evidence in developing public health policies - A policy analysis
Ethnic disparities in acquiring 2009 pandemic H1N1 influenza
pH1N1 cases were more likely to come from certain ethnic groups compared to test-negative controls. Insights into whether these disparities arise due to social or biological factors are needed in order to understand what approaches can be taken to reduce the burden of a future influenza pandemic
Immunization information systems in Canada
Evaluation of the ability of standardized supports to improve public health response to syndromic surveillance for respiratory diseases in Canada
This study raises questions about the effectiveness of using standardized protocols to improve the performance of syndromic surveillance in a decentralized public health system. Despite efforts to create standardized protocols and engage public health agencies in the process, no significant differences in the effective use of syndromic alerts were observed beyond year 1. It also raises questions about the minimum capacity of the agency and minimu…
Limitations of administrative data to identify measles cases in Ontario, Canada
How Can We Keep Immigrant Travelers Healthy? Health Challenges Experienced by Canadian South Asian Travelers Visiting Friends and Relatives
Immigrant travelers who visit friends and relatives (VFR travelers) experience substantially higher rates of travel-related infections than other travelers, in part due to low uptake of pretravel health advice. While barriers to accessing advice have been identified, better characterization is needed to inform targeted interventions. We sought to understand how South Asian VFR travelers perceived and responded to travel-related health risks by co…
Measles Serosurveys
OPINION article Front. Public Health, 15 July 2021Sec. Infectious Diseases – Surveillance, Prevention and Treatment https://doi.org/10.3389/fpubh.2021.539325
Validating viral hepatitis B and C diagnosis codes
Exploring the reasons for low pertussis vaccine effectiveness in Ontario, Canada, 2006–2008
Accelerating the Development of Measles and Rubella Microarray Patches to Eliminate Measles and Rubella
Measles and rubella microarray patches (MR-MAPs) are critical in achieving measles and rubella eradication, a goal highly unlikely to meet with current vaccines presentations. With low commercial incentive to MAP developers, limited and uncertain funding, the need for investment in a novel manufacturing facility, and remaining questions about the source of antigen, product demand, and regulatory pathway, MR-MAPs are unlikely to be prequalified by…
Global challenges and solutions to achieving and sustaining measles and rubella elimination
Measles and rubella have long been recognized as priorities for disease prevention because of their devastating consequences for child health; hence, all World Health Organization (WHO) regions currently have a goal to eliminate measles and four out of six WHO regions have a goal to eliminate rubella. Significant global progress has been made in the twenty-first century, with more than 40% of countries in the world verified by a Regional Verifica…
Medicine (25 works) · Public health (15 works) · Environmental health (14 works) · Influenza Virus Research Studies (12 works) · Immunology (11 works) · Disease (10 works) · Internal Medicine (10 works) · Nursing (10 works) · Pandemic (10 works) · Coronavirus disease 2019 (COVID-19 (9 works)