Dan J Stein
Biographic Data
| ID | 129797 |
|---|---|
| NAME | Dan J Stein |
| GIVEN NAMES | Dan J |
| FAMILY NAME | Stein |
| SIGNATURE | STEIN D J |
| AFFILIATIONS | University of Cape Town |
| ORCID | 0000-0001-7218-7810 |
| VERIFIED | Yes |
| TOTAL WORKS | 212 |
| TOTAL CITATIONS | 262 |
| AUTHOR COUNT | 212 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1992 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 7 |
Flexible Interview for ICD-11 (FLII-11)
The World Psychiatric Association (WPA) Guideline on Schizophrenia Spectrum Disorders Management for Low- and Middle-Income Countries
There is a pressing need to address the unique challenges of managing Schizophrenia Spectrum Disorders (SSD) in Low- and Middle-Income Countries (LMICs), where mental health resources are scarce and unevenly distributed. To develop this evidence-based guideline, we conducted a systematic review of the literature, followed by three rounds of Delphi surveys with experts from LMICs. The first two Delphi rounds identified and refined priority topics,…
Patterns and predictors of the transition between minimally adequate treatment and effective treatment coverage for mental disorders
BACKGROUND: The quality of mental disorder treatment varies widely, with many patients not receiving treatments based on evidence-based guidelines. We examine data from the World Mental Health (WMH) surveys to investigate prevalence and correlates of receiving effective treatment coverage (ETC) among patients receiving minimally adequate treatment (MAT) in the 12 months before interview. METHODS: Data come from 25 WMH surveys carried out in 21 co…
Are you on the internet or using screen-based devices
The concept of ‘internet addiction’ was introduced in the 1990s and has increasingly been recognized as a clinical and public health issue. Although umbrella terms can be useful for screening, theoretical considerations, and intervention planning, the term itself has received criticism because of its conceptual heterogeneity, implying an addiction to a medium and not including a wide range of problematic behavioral patterns that are below the dia…
Health response to problematic usage of the internet
Compulsive sexual behavior may be more state-like than trait-like
Type and developmental timing of childhood adversity predicts psychopathology symptoms in a South African birth cohort
Background Childhood adversity is widespread globally and is one of the strongest predictors of later psychopathology. However, the differential effects of type and timing of childhood adversities on childhood psychopathology remain unclear, highlighting the need to explore which life-course hypotheses (sensitive periods, accumulation of exposure, and/or recency of exposure) best explain these associations. Of particular importance, there is a la…
Sexual Assertiveness and Sexual Victimization Across Different Life Stages
Objectives A growing body of research indicate that experiencing sexual victimization may be linked to lower levels of sexual assertiveness, yet significant gaps remain in understanding how this association varies across the life stages in which one is victimized, gender identities, and cultural contexts. Prior studies have primarily focused on cisgender women from Western countries, mainly examined adolescent/adult sexual assault (AASA), and emp…
Characterising Maternal Sensitivity in a High Risk, Peri-urban LMIC Context
A prolific amount of data regarding maternal sensitivity and child development outcomes comes from high income, industrialised western contexts. Sparse attention has been paid to characterising patterns or unique expressions of sensitivity as an independent topic of study globally with a glaring dearth of comparative data from LMICs including sub-Saharan Africa. We aimed to detail maternal sensitivity within the dyadic interaction between mother …
Problematic usage of the internet
Problematic usage of the internet (PUI) is an increasing global concern, leading to significant negative impacts in various levels. PUI is an umbrella term comprised of subcategories, including online gaming disorder, online gambling disorder, online buying-shopping disorder, online compulsive sexual behavior disorder, problematic usage of social media, cyberchondria, cyberbullying, and digital hoarding. With respect to the diversity of these cat…
Motives for pornography use and women's sexual wellbeing
Identification and comprehensive characterization of moral disapproval and behavioral dysregulation-based pornography-use profiles across 42 countries
Research priorities in gambling
Preliminary Remarks
Introducing Serial Circulation
This introduction coins the concept of ‘serial circulation’ by connecting Mark W. Turner’s view of the nineteenth century as an expanding yet unruly “culture of seriality” (2019) with Stephen Greenblatt’s New Historicist notion of circulating “social energy” (1988) and Benjamin Lee and Edward LiPuma’s idea of modern public spheres as “cultures of circulation” (2002). We first identify the long nineteenth century as the extended moment when advanc…
The relationship between lifetime trauma exposure and psychosis in a multi-country case-control study in Africa
Background: Exposure to traumatic events is a known risk factor for psychosis. Additionally, psychosis may be a risk factor for exposure to traumatic events. There are little data on the relationship between traumatic events and psychosis in sub-Saharan Africa, particularly in large, cross-country samples using the same instrument. Methods: In a case-control study, 21,606 adults were recruited with psychosis (cases) and 21,329 adults without any …
Iron deficiency anaemia in mothers and infants with high inflammatory burden
The scarcity of epidemiological data on anaemia in low- and middle-income countries, coupled with contrasting approaches to the assessment of iron status with inflammation, represent critical research gaps. This study characterised the prevalence and profile of iron deficiency anaemia, including adjustment for inflammation, in mothers and infants from South Africa. Mother-child dyads ( n = 394) were recruited (2021–2022) for the Khula birth cohor…
Increased risk of smoking and pain in individuals with intermittent explosive disorder in the All of Us dataset
Findings suggest that IED is associated with elevated vulnerability to both smoking and pain, independent of co-occurring depressive and anxiety disorders. These results highlight the importance of integrating tobacco cessation and pain management strategies into clinical care for individuals with IED and underscore the value of large-scale biobank data in clarifying health risks associated with psychiatric disorders
Longitudinally investigating patterns of maternal psychological distress in a South African birth cohort
Psychological distress, a broad construct that encompasses of a range of emotional difficulties—including depression and anxiety—is prevalent during pregnancy and postnatally with up to 25% of women experiencing psychological distress globally. However, this is mostly described in high income countries (HIC), with little data from low- and middle-income countries (LMICs). The aim of this study was to describe and determine latent trajectory class…
Sexual satisfaction across cultures, genders, languages, and sexual orientations
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Entitled to Love
The notion of uncommandability has been central to how we perceive our emotional lives, and particularly romantic love. According to this notion, while we can control how we treat people, we have little control over how we feel about them. The argument from uncommandability is often evoked as a way of sidestepping moral obligations regarding our romantic emotions. One challenge to uncommandability is the potential to manipulate our emotions throu…
Lessons learned from the translation of the Internalised Stigma of Mental Illness (Ismi) scale into isiXhosa for use with South African Xhosa people with schizophrenia
Internalised stigma is highly prevalent among people with mental illness. This is concerning because internalised stigma is often associated with negative consequences affecting individuals' personal, familial, social, and overall wellbeing, employment opportunities and recovery. Currently, there is no psychometrically validated instrument to measure internalised stigma among Xhosa people in their home language. Our study aimed to translate the I…
Burden of disease scenarios for 204 countries and territories, 2022–2050
BACKGROUND: Future trends in disease burden and drivers of health are of great interest to policy makers and the public at large. This information can be used for policy and long-term health investment, planning, and prioritisation. We have expanded and improved upon previous forecasts produced as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) and provide a reference forecast (the most likely future), and alternativ…
Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021
BACKGROUND: Understanding the health consequences associated with exposure to risk factors is necessary to inform public health policy and practice. To systematically quantify the contributions of risk factor exposures to specific health outcomes, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 aims to provide comprehensive estimates of exposure levels, relative health risks, and attributable burden of disease for 88 ri…
Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021
BACKGROUND: Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy worldwide are valuable metrics to gauge progress in reducing mortality rates. These estimates are particularly important following large-scale mortality spikes, such as the COVID-19 pandemic. When systematically analysed, mort…
Perceived discrimination, race and health in South Africa
Perceived discrimination and psychological well-being in the USA and South Africa
In two racialized societies, perceived discrimination acts independent of demographic factors, general stressors, social desirability bias, racial identity, and SES, to negatively affect the psychological resources of self-esteem and mastery
Risk for post-traumatic stress disorder associated with different forms of interpersonal violence in South Africa
Social determinants of psychological distress in a nationally-representative sample of South African adults
Household food insufficiency and mental health in South Africa
BACKGROUND: Both mental illness and food insufficiency are common in low and middle income countries. However, there are limited data on the relation between food insufficiency and mental disorders, despite the potential relevance of such data for the development of policy-level interventions. The relationship between food insufficiency and mental disorders within a nationally representative sample of South African adults was examined. METHODS: A…
Traditional Healer Attitudes and Beliefs Regarding Referral of the Mentally Ill to Western Doctors in South Africa
Drawing on data collected from 3 focus groups with 24 traditional healers, the aim of this qualitative study was to use the constructs of the Theory of Planned Behaviour (TPB) to gain an understanding of traditional healer referral practices of their patients with a mental illness. Results indicated that traditional healers possess a concept of mental illness, mainly referring to a patient behaving abnormally. They often report regularly treating…
Race and Psychological Distress
We analyze data from the South African Stress and Health Study, a nationally representative in-person psychiatric epidemiologic survey of 4,351 adults conducted as part of the World Mental Health Survey Initiative between January 2002 and June 2004. All blacks (Africans, Coloreds, and Indians) initially report higher levels of non-specific distress and anger/hostility than whites. Access to socioeconomic resources helps explain differences in non…
Investigating tangible and mental resources as predictors of perceived household food insecurity during pregnancy among women in a South African birth cohort study
Why Do People Watch Pornography? Cross-Cultural Validation of the Pornography Use Motivations Scale (Pums) and Its Short Form (Pums-8)
Motivations for pornography use may vary across gender identities, sexual orientations, and geographical regions, warranting examination to promote individual and public health. The aims of this study were to validate the Pornography Use Motivations Scale (PUMS) in a diverse, multicultural sample, and develop a short form (PUMS-8) that can assess a wide range of pornography use motivations. Using data from 42 countries (N = 75,117; Mage = 32.07; …
Cross-cultural Validation of the Arizona Sexual Experience Scale (Asex) in 42 Countries and 26 Languages
Introduction The Arizona Sexual Experiences Scale (ASEX) is a brief questionnaire that evaluates five major aspects of sexual function: sex drive, arousal, erectile function/vaginal lubrication, ability to reach orgasm, and satisfaction with orgasm. An advantage of the ASEX is its simplicity and brevity (five items), making it suitable for the screening of sexual function problems in healthcare contexts and large-scale studies. The main objective…
Does genetics matter for disease-related stigma? The impact of genetic attribution on stigma associated with rheumatic heart disease in the Western Cape, South Africa
Tolerance for physical pain in suicidal subjects
This study investigated the tolerance for physical pain in suicidal subjects. Suicidal, psychiatric nonsuicidal, and normal young males and females were administered pain measures including electric shocks, appraisal of shocks, and a measure of thermal pain. Additional study variables included diagnosis, past suicide attempts, severity of suicidal intent, and length of hospitalization. Suicidal individuals showed higher tolerance for pain and app…
Mental health and academic failure among first-year university students in South Africa
Universities in South Africa face ongoing challenges with low rates of academic attainment and high rates of attrition. Our aims were to (1) investigate the extent to which common mental disorders evaluated early in the first year predict academic failure at the end of the year, controlling for sociodemographic factors and (2) establish the potential reduction in prevalence of failure that could be achieved by effectively treating associated ment…
Reducing nonfatal suicidal behaviour among university students
Campus-based suicide prevention is an important priority for universities. One approach could be to identify and treat common mental disorders, but it is unclear what potential reduction in suicide might be achieved by such an approach. Our aim was to quantify this potential effect on prevalence of nonfatal suicidal behaviour among first-year students. Data were collected from students at two South African universities ( N = 633) via an online su…
Epidemiology of non-fatal suicidal behavior among first-year university students in South Africa
Supplemental data for this article can be accessed on the publisher's website.We used a cross-sectional web-based survey and discrete-time survival analysis with person-year as unit of analysis and retrospective age-of-onset reports to estimate prevalence and predictors of suicidal ideation, plan, and attempt, and transitions from ideation to plan and attempt among South African university students ( n = 1402). The lifetime prevalence of ideation…
Men's exposure to human rights violations and relations with perpetration of intimate partner violence in South Africa
BACKGROUND: Despite widespread apartheid-related human rights violations (HRV) and intimate partner violence (IPV) in South Africa, research investigating the influence of HRV on IPV perpetration is scarce. METHODS: This study analysed data from the South Africa Stress and Health Study, a cross-sectional survey conducted from 2003 to 2004 with 4351 South Africans examining public health concerns associated with apartheid. Analyses were restricted…
Cognitive Stimulation and Cognitive and Functional Decline in Alzheimer's Disease
Active involvement in cognitively stimulating pursuits may be beneficial for persons with AD
The mental health impact of Aids-related mortality in South Africa
BACKGROUND: Few data exist on how the HIV/AIDS epidemic may influence population mental health. The associations were examined between knowing someone who died of HIV/AIDS and common mental disorders among South African adults. METHODS: Between 2002 and 2004, a nationally representative sample of 4351 adults were interviewed about personally knowing someone who died of HIV/AIDS, and the World Health Organization Composite International Diagnostic…
Cross-Cultural Validation of the Sexual Desire Inventory (SDI-2) in 42 Countries and 26 Languages
Sexual desire is a complex construct with important implications for sexual functioning and well-being. In this research, we translated the Sexual Desire Inventory (SDI-2), a widely used scale for assessing sexual (desire), into 25 languages from English and used data from the International Sex Survey (ISS) to (a) investigate its psychometric properties (i.e. factorial structure, reliability, validity, and measurement invariance) and (b) explore …
The role of causal knowledge in stigma considerations in African genomics research
Building resilient families
Depression contributes significantly to the global burden of disease in low- and middle-income countries. In South Africa, individuals may be at elevated risk for depression due to HIV and AIDS, violence, and poverty. For adolescents, resilience-focused prevention strategies have the potential to reduce onset of depression. Involving families in promoting adolescent mental health is developmentally appropriate, but few existing interventions take…
A pilot study of a nurse-delivered cognitive behavioral therapy intervention (Ziphamandla) for adherence and depression in HIV in South Africa
Depression is prevalent among people living with HIV in South Africa and interferes with adherence to antiretroviral therapy. This study evaluated a nurse-delivered, cognitive behavioral therapy intervention for adherence and depression among antiretroviral therapy users with depression in South Africa ( n = 14). Primary outcomes were depression, antiretroviral therapy adherence, feasibility, and acceptability. Findings support robust improvement…
Suicide in Judaism with a Special Emphasis on Modern Israel
Judaism considers the duty of preserving life as a paramount injunction. Specific injunctions against suicide appear in the Bible, Talmud, and thereafter. Nevertheless, Jewish tradition emphasizes that one should let himself be killed rather than violate cardinal rules of Jewish law. Mitigating circumstances are found for the six deaths by suicide mentioned in the Bible, for example to account for one's sins, or avoid shameful death. Heroic suici…
Adversities in childhood and adult psychopathology in the South Africa Stress and Health Study
Psychoanalysis and Cognitive Science
Although the relationship between psychoanalysis and cognitive science has begun to be addressed, theorists have not constructed a unifying conceptual framework from which to compare and contrast these disciplines. This paper begins by considering the models of mind of cognitive science, and of classical and contemporary psychoanalysis. It is argued that it is useful to reformulate psychoanalytic constructs in terms of cognitive science models. P…
Tolerance for physical pain in suicidal subjects
This study investigated the tolerance for physical pain in suicidal subjects. Suicidal, psychiatric nonsuicidal, and normal young males and females were administered pain measures including electric shocks, appraisal of shocks, and a measure of thermal pain. Additional study variables included diagnosis, past suicide attempts, severity of suicidal intent, and length of hospitalization. Suicidal individuals showed higher tolerance for pain and app…
Trichobezoars in Trichotillomania
OBJECTIVE: Although trichobezoars are well described in the surgical literature, there is relatively little in the psychiatric literature on them. This study aims to focus the attention of readers on trichobezoars by means of a case report and an overview of the literature. METHOD: We present a case of a patient with trichotillomania and a trichobezoar, including psychiatric management. We also briefly review the relevant literature. RESULTS: Hai…
Autistic Subjects with Comorbid Epilepsy
The Neurobiology of Evil
Events such as the Nuremberg Trials in Germany, or the Truth and Reconciliation Commission proceedings in South Africa, raise questions about the psychology of perpetrators of crimes against humanity. While such violations occur within particular socio-political contexts, given the significant advances in clinical neuroscience in the past several decades, is it possible to outline a 'psychobiology of evil'? In this paper a preliminary approach to…
Mental Health Beyond the Truth and Reconciliation Commission
Mental Health Beyond the Truth and Reconciliation Commission." Ethnicity & Health, 5(3-4), pp. 189–190
Determinants of unprotected sex among HIV-positive patients in South Africa
This study examined the prevalence of unprotected sex, other sexual risk behaviours, and factors associated with unprotected sex among men and women recently diagnosed with HIV in South Africa. One hundred and forty-nine outpatients (44 males and 105 females) were assessed, of whom 101 were sexually active at least 6 months prior to study entry. Subjects were asked about sexual risk behaviours with reference to their most recent sexual encounter.…
Post-traumatic stress disorder among recently diagnosed patients with HIV/Aids in South Africa
This study examined the prevalence of and factors associated with post-traumatic stress disorder in recently diagnosed HIV/AIDS patients in South Africa. One hundred and forty-nine (44 male, 105 female) recently diagnosed HIV/AIDS patients (mean duration since diagnosis = 5.8 months, SD = 4.1) were evaluated. Subjects were assessed using the MINI International Neuropsychiatric Interview (MINI), the Carver Brief COPE coping scale and the Sheehan D…
Sexual risk factors associated with volunteering for HIV vaccine research in South Africa
There are few data on how the risk profiles of individuals who volunteer for HIV vaccine research compare to the general population from which participants are recruited. This study contrasts demographic and sexual risk behaviours among volunteers in an HIV vaccine preparedness cohort with data from a cross-sectional community survey conducted in the same peri-urban community during the same time period. For the HIV vaccine preparedness cohort, s…
Factors Associated with Self-evaluated Severity of Illness and Quality of Life in Male Israeli Asthmatic Soldiers
Common Mental Disorders among HIV-Infected Individuals in South Africa
Despite the high prevalence of both mental disorders and HIV infection in much of sub-Saharan Africa, little is known about the occurrence of mental health disorders among HIV-infected individuals. We conducted a cross-sectional study among individuals enrolled into HIV care and treatment services near Cape Town, South Africa. Psychiatric diagnoses were measured using the Mini-International Neuropsychiatric Interview (MINI) administered by traine…
Toward a Global View of Alcohol, Tobacco, Cannabis, and Cocaine Use
BACKGROUND: Alcohol, tobacco, and illegal drug use cause considerable morbidity and mortality, but good cross-national epidemiological data are limited. This paper describes such data from the first 17 countries participating in the World Health Organization's (WHO's) World Mental Health (WMH) Survey Initiative. METHODS AND FINDINGS: Household surveys with a combined sample size of 85,052 were carried out in the Americas (Colombia, Mexico, United…
Twelve-month mental disorders in South Africa
Background South Africa's history and current social conditions suggest that mental disorders are likely to be a major contributor to disease burden, but there has been no national study using standardized assessment tools. Method The South African Stress and Health Study was a nationally representative in-person psychiatric epidemiological survey of 4351 adults (aged ⩾18 years) that was conducted as part of the WHO World Mental Health (WMH) Surv…
Social anxiety disorder
The relationship between behavioural inhibition, anxiety disorders, depression and CD4 counts in HIV-positive adults
This study examined the relationships between behavioural inhibition (BI), anxiety disorders, depression and CD4 counts in 456 HIV-infected adults attending primary healthcare HIV clinics in South Africa. Our first hypothesis was that BI would be positively correlated with anxiety disorders and with depression. Our second hypothesis was that BI, anxiety disorders and depression would be negatively correlated with CD4 counts. Participants complete…
The Trichotillomania Scale for Children
Social determinants of psychological distress in a nationally-representative sample of South African adults
Perceived discrimination, race and health in South Africa
Risk for post-traumatic stress disorder associated with different forms of interpersonal violence in South Africa
Cumulative effect of multiple trauma on symptoms of posttraumatic stress disorder, anxiety, and depression in adolescents
Validity of the K-10 in detecting DSM-IV-defined depression and anxiety disorders among HIV-infected individuals
It has been suggested that an HIV diagnosis may increase the likelihood of mental disorders among infected individuals and that the progression of HIV may be hastened by mental disorders like anxiety and depression. Therefore, a brief screening measure, with good sensitivity/specificity for psychiatric diagnoses that could be given to HIV-infected individuals would be useful. We assessed the validity of the K-10, using the MINI International Neur…
Clinical Correlates of HIV-Associated Neurocognitive Disorders in South Africa
The mental health impact of Aids-related mortality in South Africa
BACKGROUND: Few data exist on how the HIV/AIDS epidemic may influence population mental health. The associations were examined between knowing someone who died of HIV/AIDS and common mental disorders among South African adults. METHODS: Between 2002 and 2004, a nationally representative sample of 4351 adults were interviewed about personally knowing someone who died of HIV/AIDS, and the World Health Organization Composite International Diagnostic…
Treatment Monitoring
The epidemiology of obsessive-compulsive disorder in the National Comorbidity Survey Replication
Medicine (150 works) · Psychology (109 works) · Psychiatry (106 works) · Environmental health (77 works) · Clinical Psychology (67 works) · Population (58 works) · Mental health (57 works) · Demography (49 works) · Public health (46 works) · Clinical Psychology (35 works)