Charles P O’brien
Biographic Data
| ID | 229226 |
|---|---|
| NAME | Charles P O’brien |
| GIVEN NAMES | Charles P |
| FAMILY NAME | O’brien |
| SIGNATURE | O’BRIEN C P |
| AFFILIATIONS | University of Pennsylvania |
| VERIFIED | No |
| TOTAL WORKS | 12 |
| TOTAL CITATIONS | 16 |
| AUTHOR COUNT | 12 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1978 |
| LATEST PUBLICATION YEAR | 2018 |
| H-INDEX | 2 |
Personal Control Over Decisions to Participate in Research by Persons With Histories of Both Substance Use Disorders and Criminal Justice Supervision
Individuals must feel free to exert personal control over decisions regarding research participation. We present an examination of participants' perceived personal control over, as well as reported pressures and threats from others, influencing their decision to join a study assessing the effectiveness of extended-release naltrexone in preventing opioid dependence relapse. Most participants endorsed a strong sense of control over the decision; fe…
Film History
An international consensus for assessing internet gaming disorder using the new DSM ‐5 approach
AIMS: For the first time, the Diagnostic and Statistical Manual for Mental Disorders (DSM-5) introduces non-substance addictions as psychiatric diagnoses. The aims of this paper are to (i) present the main controversies surrounding the decision to include internet gaming disorder, but not internet addiction more globally, as a non-substance addiction in the research appendix of the DSM-5, and (ii) discuss the meaning behind the DSM-5 criteria for…
DSM-5 Criteria for Substance Use Disorders
Since DSM-IV was published in 1994, its approach to substance use disorders has come under scrutiny. Strengths were identified (notably, reliability and validity of dependence), but concerns have also arisen. The DSM-5 Substance-Related Disorders Work Group considered these issues and recommended revisions for DSM-5. General concerns included whether to retain the division into two main disorders (dependence and abuse), whether substance use diso…
Drug Dependence, a Chronic Medical Illness
The effects of drug dependence on social systems has helped shape the generally held view that drug dependence is primarily a social problem, not a health problem. In turn, medical approaches to prevention and treatment are lacking. We examined evidence that drug (including alcohol) dependence is a chronic medical illness. A literature review compared the diagnoses, heritability, etiology (genetic and environmental factors), pathophysiology, and …
Crack and the Evolution of Anti-Drug Policy
Under the Influence? Drugs and the American Work Force
Drug use in the workplace, its effect on performance and safety, and the role of workplace drug testing has received much attention in the popular press. But what do we actually know about this troubling issue?With an extensive and readable overview of the literature, the committee presents what we do know by examining the major issues: The extent and severity of drug use on and off the job. The strengths and weaknesses of methods for detecting d…
Child of Paradise
The Relation of Plasma Androgen Levels to Sexual Behaviors and Attitudes of Women1
Four androgens: dehydroepiandrosterone (DHEA), androstenedione (A), testosterone (T), and dihydrotestosterone (DHT), a variety of sexual behaviors and attitudes, and several moods were determined regularly in two groups of healthy, married women who differed by three decades in age. The younger women exhibited significantly higher levels of each androgen, the differences being almost entirely attributable to ovarian failure in the older group. Al…
Absence of Naloxone Sensitivity in Obese Humans
Studies in rodents suggest the possibility of an association between elevated endogenous opiate activity and overeating and obesity. One measure of elevated opiate activity is sensitivity to the opiate antagonist naloxone. Seven massively obese human subjects showed no subjective or physiological sensitivity to large intravenous doses of naloxone. This finding fails to support a relationship between elevated endorphin activity and human obesity
The Relationship of Plasma Estradiol Level to Sexual Behavior in Young Women
Persky, Harold PhD*; Charney, Natalie; Lief, Harold I. MD; O'Brien, Charles P. MD, PhD; Miller, William R. PhD; Strauss, Dorothy PhD† Author Information
Plasma testosterone level and sexual behavior of couples
Plasma testosterone level and sexual behavior of couples
Personal Control Over Decisions to Participate in Research by Persons With Histories of Both Substance Use Disorders and Criminal Justice Supervision
Individuals must feel free to exert personal control over decisions regarding research participation. We present an examination of participants' perceived personal control over, as well as reported pressures and threats from others, influencing their decision to join a study assessing the effectiveness of extended-release naltrexone in preventing opioid dependence relapse. Most participants endorsed a strong sense of control over the decision; fe…
The Relationship of Plasma Estradiol Level to Sexual Behavior in Young Women
Persky, Harold PhD*; Charney, Natalie; Lief, Harold I. MD; O'Brien, Charles P. MD, PhD; Miller, William R. PhD; Strauss, Dorothy PhD† Author Information
Plasma testosterone level and sexual behavior of couples
The Relation of Plasma Androgen Levels to Sexual Behaviors and Attitudes of Women1
Four androgens: dehydroepiandrosterone (DHEA), androstenedione (A), testosterone (T), and dihydrotestosterone (DHT), a variety of sexual behaviors and attitudes, and several moods were determined regularly in two groups of healthy, married women who differed by three decades in age. The younger women exhibited significantly higher levels of each androgen, the differences being almost entirely attributable to ovarian failure in the older group. Al…
Absence of Naloxone Sensitivity in Obese Humans
Studies in rodents suggest the possibility of an association between elevated endogenous opiate activity and overeating and obesity. One measure of elevated opiate activity is sensitivity to the opiate antagonist naloxone. Seven massively obese human subjects showed no subjective or physiological sensitivity to large intravenous doses of naloxone. This finding fails to support a relationship between elevated endorphin activity and human obesity
Child of Paradise
Crack and the Evolution of Anti-Drug Policy
Under the Influence? Drugs and the American Work Force
Drug use in the workplace, its effect on performance and safety, and the role of workplace drug testing has received much attention in the popular press. But what do we actually know about this troubling issue?With an extensive and readable overview of the literature, the committee presents what we do know by examining the major issues: The extent and severity of drug use on and off the job. The strengths and weaknesses of methods for detecting d…
Drug Dependence, a Chronic Medical Illness
The effects of drug dependence on social systems has helped shape the generally held view that drug dependence is primarily a social problem, not a health problem. In turn, medical approaches to prevention and treatment are lacking. We examined evidence that drug (including alcohol) dependence is a chronic medical illness. A literature review compared the diagnoses, heritability, etiology (genetic and environmental factors), pathophysiology, and …
DSM-5 Criteria for Substance Use Disorders
Since DSM-IV was published in 1994, its approach to substance use disorders has come under scrutiny. Strengths were identified (notably, reliability and validity of dependence), but concerns have also arisen. The DSM-5 Substance-Related Disorders Work Group considered these issues and recommended revisions for DSM-5. General concerns included whether to retain the division into two main disorders (dependence and abuse), whether substance use diso…
An international consensus for assessing internet gaming disorder using the new DSM ‐5 approach
AIMS: For the first time, the Diagnostic and Statistical Manual for Mental Disorders (DSM-5) introduces non-substance addictions as psychiatric diagnoses. The aims of this paper are to (i) present the main controversies surrounding the decision to include internet gaming disorder, but not internet addiction more globally, as a non-substance addiction in the research appendix of the DSM-5, and (ii) discuss the meaning behind the DSM-5 criteria for…
Film History
Personal Control Over Decisions to Participate in Research by Persons With Histories of Both Substance Use Disorders and Criminal Justice Supervision
Individuals must feel free to exert personal control over decisions regarding research participation. We present an examination of participants' perceived personal control over, as well as reported pressures and threats from others, influencing their decision to join a study assessing the effectiveness of extended-release naltrexone in preventing opioid dependence relapse. Most participants endorsed a strong sense of control over the decision; fe…
Psychology (7 works) · Medicine (6 works) · Internal Medicine (4 works) · Psychiatry (4 works) · Developmental psychology (3 works) · Drug (3 works) · Endocrinology (3 works) · Endocrinology (3 works) · Internal Medicine (3 works) · Political science (3 works)