Harshpal Singh Sachdev
Biographic Data
| ID | 230458 |
|---|---|
| NAME | Harshpal Singh Sachdev |
| GIVEN NAMES | Harshpal Singh |
| FAMILY NAME | Sachdev |
| SIGNATURE | SACHDEV H S |
| AFFILIATIONS | Sitaram Bhartia Institute of Science and Research |
| ORCID | 0000-0002-4956-9391 |
| VERIFIED | Yes |
| TOTAL WORKS | 28 |
| TOTAL CITATIONS | 21 |
| AUTHOR COUNT | 28 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2007 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 3 |
Prayas
Purpose: The PRAYAS Individual Patient Data Meta-analysis (IPD-MA) database aims to estimate the prevalence of anemia among children under 18 years, non-pregnant and non-lactating (NPNL) women, and pregnant women (by trimester), with further stratification by age group, year, and region of India. Beyond prevalence, it seeks to address the etiological contribution of iron and other erythropoietic micronutrient deficiencies and to evaluate the effe…
The role of antioxidant nutrients in mitigating PM2.5-related health risks in young Indian children
Introduction Pollution (PM 2.5 ) exposure can result in acute respiratory illness (ARI) and anaemia in children. We aimed to investigate if antioxidant nutrient intakes could mitigate the impact of PM 2.5 on child health outcomes on a national scale in India. Methods We triangulated satellite-derived PM 2.5 exposure data at the primary sampling unit level, with ARI and anaemia prevalence data from national district-level survey, and antioxidant n…
The role of dairy consumption in the relationship between wealth and early life physical growth in India
The analysis of triangulated survey data shows that household level per- adult female equivalent dairy consumption positively modified the association between wealth index and HAZ, suggesting that regular inclusion of milk and milk products in the diets of children from households across all wealth quintiles could improve linear growth in this population
Characterisation of anaemia amongst school going adolescent girls in rural Haryana, India
Objective: High burden of anaemia exists amongst rural adolescent girls in India. The objective of this study was to characterise anaemia in school going adolescent girls in rural Haryana, India. Design: Linear and multiple logistic regression analysis of data collected prior to an intervention trial was conducted. Participants were classified into anaemic (haemoglobin 12 , mixed, anaemia of other causes and inflammation. Setting: Three schools i…
Changes in asset-based wealth across the life course in birth cohorts from five low- and middle-income countries
Temporally-harmonized asset indices displayed coherence with cross-sectional indices as well as construct validity with schooling
Predictors of recovery in children aged 6–59 months with uncomplicated severe acute malnutrition
Objective: To identify predictors of recovery in children with uncomplicated severe acute malnutrition (SAM). Design: This is a secondary data analysis from an individual randomised controlled trial, where children with uncomplicated SAM were randomised to three feeding regimens, namely ready-to-use therapeutic food (RUTF) sourced from Compact India, locally prepared RUTF or augmented home-prepared foods, under two age strata (6–17 months and 18–…
Reply to J Sheftel et al. and N Arlappa
A future for the world's children? A WHO–Unicef–Lancet Commission
Despite dramatic improvements in survival, nutrition, and education over recent decades, today's children face an uncertain future. Climate change, ecological degradation, migrating populations, conflict, pervasive inequalities, and predatory commercial practices threaten the health and future of children in every country. In 2015, the world's countries agreed on the Sustainable Development Goals (SDGs), yet nearly 5 years later, few countries ha…
Effect of home-based newborn care on neonatal and infant mortality
BACKGROUND: Home-based newborn care has been found to reduce neonatal mortality in rural areas. Study evaluated effectiveness of home-based care delivered by specially recruited newborn care workers- Shishu Rakshak (SR) and existing workers- anganwadi workers (AWW) in reducing neonatal and infant mortality rates. METHODS: This three-arm, community-based, cluster randomised trial was conducted in five districts in India. Intervention package consi…
An uncertainty estimate of the prevalence of stunting in national surveys
This study proposes a robust statistical method to estimate uncertainty in stunting prevalence estimates due to incongruent dispersions of height measured in national surveys for children < 5 years in relation to the WHO height-for-age standard. The uncertainty is partly due to population heterogeneity, but also due to measurement precision, and calls for better quality in these measurements
Association of birth outcomes and postnatal growth with adult leukocyte telomere length
Born small for gestational age due to undernutrition in utero and subsequent catch-up growth is associated with risk of developing chronic diseases in adulthood. Telomere length has been shown to be a predictor of these age-related diseases and may be a link between birth size, a surrogate for foetal undernutrition, and adult chronic diseases. We assessed the relationship of leukocyte telomere length in adult life with birth outcomes and serial c…
Mid-upper arm circumference in detection of weight-for-height Z -score below −3 in children aged 6–59 months
Objective To evaluate the predictive ability of mid-upper arm circumference (MUAC) for detecting severe wasting (weight-for-height Z -score (WHZ) Design Cross-sectional survey. Setting Rural Uttar Pradesh, India. Subjects Children ( n 18 456) for whom both WHZ ( n 18 463) and MUAC were available. Results The diagnostic test accuracy of MUAC for severe wasting was excellent (area under receiver-operating characteristic curve = 0·933). Across the l…
Association between maternal age at childbirth and child and adult outcomes in the offspring
BACKGROUND: Both young and advanced maternal age is associated with adverse birth and child outcomes. Few studies have examined these associations in low-income and middle-income countries (LMICs) and none have studied adult outcomes in the offspring. We aimed to examine both child and adult outcomes in five LMICs. METHODS: In this prospective study, we pooled data from COHORTS (Consortium for Health Orientated Research in Transitioning Societies…
Parental childhood growth and offspring birthweight
OBJECTIVE: Associations between parental and offspring size at birth are well established, but the relative importance of parental growth at different ages as predictors of offspring birthweight is less certain. Here we model parental birthweight and postnatal conditional growth in specific age periods as predictors of offspring birthweight. METHODS: We analyzed data from 3,392 adults participating in four prospective birth cohorts and 5,506 of t…
Are village health sanitation and nutrition committees fulfilling their roles for decentralised health planning and action? A mixed methods study from rural eastern India
Our study suggests that VHSNCs perform few of their specified functions for decentralized planning and action. If VHSNCs are to be instrumental in improving community health, sanitation and nutrition, they need education, mobilisation and monitoring for formal links with the wider health system
Participatory women’s groups and counselling through home visits to improve child growth in rural eastern India
ISRCTN register 51505201 ; Clinical Trials Registry of India number 2014/06/004664
Resolution of Bitot's spots following mega-dose vitamin A supplementation in children between 1 and 5 years of age
Objective The prevalence of Bitot's spots (BS) is often used to quantify vitamin A deficiency burden in India, both before and after mega-dose vitamin A supplementation (MVAS) programmes. However, the proportion of BS cured following this intervention is unclear in contemporary times. The current study evaluated the responsiveness of BS over 1 year to MVAS administered as per the national programme in rural India. Design Prospective, community-ba…
Associations of linear growth and relative weight gain during early life with adult health and human capital in countries of low and middle income
Maternal Height and Child Growth Patterns
OBJECTIVE: To examine associations between maternal height and child growth during 4 developmental periods: intrauterine, birth to age 2 years, age 2 years to mid-childhood (MC), and MC to adulthood. STUDY DESIGN: Pooled analysis of maternal height and offspring growth using 7630 mother-child pairs from 5 birth cohorts (Brazil, Guatemala, India, the Philippines, and South Africa). We used conditional height measures that control for collinearity …
Setting research priorities to reduce global mortality from preterm birth and low birth weight by 2015
Birth weight, postnatal weight gain, and adult body composition in five low and middle income countries
OBJECTIVES: To evaluate the associations between birth weight (BW), infancy, and childhood weight gain and adult body composition. METHODS: Subjects included participants of five birth cohort studies from low and middle income nations (Brazil, Guatemala, India, Philippines, and South Africa; n = 3432). We modeled adult body composition as a function of BW and conditional weight gain (CW), representing changes in weight trajectory relative to peer…
Technical note
The Maresh reference data on stature and long bone lengths in a sample of healthy middle‐class children from Denver, Colorado [Maresh: Am J Dis Child 66 ( 1943 ) 227–257; Maresh: Am J Dis Child 89 ( 1955 ) 725–742; Maresh: Human growth and development ( 1970 ) p 155–200], have been used extensively by biological anthropologists to estimate juvenile age and body size using skeletal elements and to assess growth in skeletal series from different et…
Growth patterns in early childhood and final attained stature
Growth failure is cumulative, and short stature is associated with multiple indices of reduced human capital. Few studies have been able to address in a single analysis both consideration of the timing of growth failure and comparison across populations. We analyzed data from birth cohorts in Brazil, Guatemala, India, the Philippines, and South Africa ( n = 4,659). We used data on length at birth (available for three of the five cohorts), 12 mo, …
Maternal and child undernutrition
Guidance on publishing results and how we operate evidence-based policy
An abstract is not available for this content. As you have access to this content, full HTML content is provided on this page. A PDF of this content is also available in through the ‘Save PDF’ action button
Technical note
The Maresh reference data on stature and long bone lengths in a sample of healthy middle‐class children from Denver, Colorado [Maresh: Am J Dis Child 66 ( 1943 ) 227–257; Maresh: Am J Dis Child 89 ( 1955 ) 725–742; Maresh: Human growth and development ( 1970 ) p 155–200], have been used extensively by biological anthropologists to estimate juvenile age and body size using skeletal elements and to assess growth in skeletal series from different et…
Potential impacts of iron biofortification in India
Genetic Engineering for the Poor
Plant breeding to control zinc deficiency in India
Objective To estimate the potential impact of zinc biofortification of rice and wheat on public health in India and to evaluate its cost-effectiveness compared with alternative interventions and international standards. Design The burden of zinc deficiency (ZnD) in India was expressed in disability-adjusted life years (DALYs) lost. Current zinc intakes were derived from a nationally representative household food consumption survey (30-day recall)…
Genetic Engineering for the Poor
Maternal and child undernutrition
Guidance on publishing results and how we operate evidence-based policy
An abstract is not available for this content. As you have access to this content, full HTML content is provided on this page. A PDF of this content is also available in through the ‘Save PDF’ action button
Potential impacts of iron biofortification in India
Growth patterns in early childhood and final attained stature
Growth failure is cumulative, and short stature is associated with multiple indices of reduced human capital. Few studies have been able to address in a single analysis both consideration of the timing of growth failure and comparison across populations. We analyzed data from birth cohorts in Brazil, Guatemala, India, the Philippines, and South Africa ( n = 4,659). We used data on length at birth (available for three of the five cohorts), 12 mo, …
Setting research priorities to reduce global mortality from preterm birth and low birth weight by 2015
Birth weight, postnatal weight gain, and adult body composition in five low and middle income countries
OBJECTIVES: To evaluate the associations between birth weight (BW), infancy, and childhood weight gain and adult body composition. METHODS: Subjects included participants of five birth cohort studies from low and middle income nations (Brazil, Guatemala, India, Philippines, and South Africa; n = 3432). We modeled adult body composition as a function of BW and conditional weight gain (CW), representing changes in weight trajectory relative to peer…
Technical note
The Maresh reference data on stature and long bone lengths in a sample of healthy middle‐class children from Denver, Colorado [Maresh: Am J Dis Child 66 ( 1943 ) 227–257; Maresh: Am J Dis Child 89 ( 1955 ) 725–742; Maresh: Human growth and development ( 1970 ) p 155–200], have been used extensively by biological anthropologists to estimate juvenile age and body size using skeletal elements and to assess growth in skeletal series from different et…
Associations of linear growth and relative weight gain during early life with adult health and human capital in countries of low and middle income
Maternal Height and Child Growth Patterns
OBJECTIVE: To examine associations between maternal height and child growth during 4 developmental periods: intrauterine, birth to age 2 years, age 2 years to mid-childhood (MC), and MC to adulthood. STUDY DESIGN: Pooled analysis of maternal height and offspring growth using 7630 mother-child pairs from 5 birth cohorts (Brazil, Guatemala, India, the Philippines, and South Africa). We used conditional height measures that control for collinearity …
Resolution of Bitot's spots following mega-dose vitamin A supplementation in children between 1 and 5 years of age
Objective The prevalence of Bitot's spots (BS) is often used to quantify vitamin A deficiency burden in India, both before and after mega-dose vitamin A supplementation (MVAS) programmes. However, the proportion of BS cured following this intervention is unclear in contemporary times. The current study evaluated the responsiveness of BS over 1 year to MVAS administered as per the national programme in rural India. Design Prospective, community-ba…
Association between maternal age at childbirth and child and adult outcomes in the offspring
BACKGROUND: Both young and advanced maternal age is associated with adverse birth and child outcomes. Few studies have examined these associations in low-income and middle-income countries (LMICs) and none have studied adult outcomes in the offspring. We aimed to examine both child and adult outcomes in five LMICs. METHODS: In this prospective study, we pooled data from COHORTS (Consortium for Health Orientated Research in Transitioning Societies…
Parental childhood growth and offspring birthweight
OBJECTIVE: Associations between parental and offspring size at birth are well established, but the relative importance of parental growth at different ages as predictors of offspring birthweight is less certain. Here we model parental birthweight and postnatal conditional growth in specific age periods as predictors of offspring birthweight. METHODS: We analyzed data from 3,392 adults participating in four prospective birth cohorts and 5,506 of t…
Are village health sanitation and nutrition committees fulfilling their roles for decentralised health planning and action? A mixed methods study from rural eastern India
Our study suggests that VHSNCs perform few of their specified functions for decentralized planning and action. If VHSNCs are to be instrumental in improving community health, sanitation and nutrition, they need education, mobilisation and monitoring for formal links with the wider health system
Participatory women’s groups and counselling through home visits to improve child growth in rural eastern India
ISRCTN register 51505201 ; Clinical Trials Registry of India number 2014/06/004664
Mid-upper arm circumference in detection of weight-for-height Z -score below −3 in children aged 6–59 months
Objective To evaluate the predictive ability of mid-upper arm circumference (MUAC) for detecting severe wasting (weight-for-height Z -score (WHZ) Design Cross-sectional survey. Setting Rural Uttar Pradesh, India. Subjects Children ( n 18 456) for whom both WHZ ( n 18 463) and MUAC were available. Results The diagnostic test accuracy of MUAC for severe wasting was excellent (area under receiver-operating characteristic curve = 0·933). Across the l…
Association of birth outcomes and postnatal growth with adult leukocyte telomere length
Born small for gestational age due to undernutrition in utero and subsequent catch-up growth is associated with risk of developing chronic diseases in adulthood. Telomere length has been shown to be a predictor of these age-related diseases and may be a link between birth size, a surrogate for foetal undernutrition, and adult chronic diseases. We assessed the relationship of leukocyte telomere length in adult life with birth outcomes and serial c…
A future for the world's children? A WHO–Unicef–Lancet Commission
Despite dramatic improvements in survival, nutrition, and education over recent decades, today's children face an uncertain future. Climate change, ecological degradation, migrating populations, conflict, pervasive inequalities, and predatory commercial practices threaten the health and future of children in every country. In 2015, the world's countries agreed on the Sustainable Development Goals (SDGs), yet nearly 5 years later, few countries ha…
Effect of home-based newborn care on neonatal and infant mortality
BACKGROUND: Home-based newborn care has been found to reduce neonatal mortality in rural areas. Study evaluated effectiveness of home-based care delivered by specially recruited newborn care workers- Shishu Rakshak (SR) and existing workers- anganwadi workers (AWW) in reducing neonatal and infant mortality rates. METHODS: This three-arm, community-based, cluster randomised trial was conducted in five districts in India. Intervention package consi…
An uncertainty estimate of the prevalence of stunting in national surveys
This study proposes a robust statistical method to estimate uncertainty in stunting prevalence estimates due to incongruent dispersions of height measured in national surveys for children < 5 years in relation to the WHO height-for-age standard. The uncertainty is partly due to population heterogeneity, but also due to measurement precision, and calls for better quality in these measurements
Changes in asset-based wealth across the life course in birth cohorts from five low- and middle-income countries
Temporally-harmonized asset indices displayed coherence with cross-sectional indices as well as construct validity with schooling
Predictors of recovery in children aged 6–59 months with uncomplicated severe acute malnutrition
Objective: To identify predictors of recovery in children with uncomplicated severe acute malnutrition (SAM). Design: This is a secondary data analysis from an individual randomised controlled trial, where children with uncomplicated SAM were randomised to three feeding regimens, namely ready-to-use therapeutic food (RUTF) sourced from Compact India, locally prepared RUTF or augmented home-prepared foods, under two age strata (6–17 months and 18–…
Reply to J Sheftel et al. and N Arlappa
Characterisation of anaemia amongst school going adolescent girls in rural Haryana, India
Objective: High burden of anaemia exists amongst rural adolescent girls in India. The objective of this study was to characterise anaemia in school going adolescent girls in rural Haryana, India. Design: Linear and multiple logistic regression analysis of data collected prior to an intervention trial was conducted. Participants were classified into anaemic (haemoglobin 12 , mixed, anaemia of other causes and inflammation. Setting: Three schools i…
Medicine (23 works) · Child Nutrition and Water Access (21 works) · Environmental health (13 works) · Birth, Development, and Health (11 works) · Demography (11 works) · Biology (10 works) · Pregnancy (8 works) · Internal Medicine (7 works) · Population (7 works) · Birth weight (6 works)