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Mark Helfand

Biographic Data

ID2461117
NAMEMark Helfand
GIVEN NAMESMark
FAMILY NAMEHelfand
SIGNATUREHELFAND M
AFFILIATIONSOregon Health & Science University
ORCID0000-0003-4846-9900
VERIFIEDYes
TOTAL WORKS10
TOTAL CITATIONS12
AUTHOR COUNT10
EDITOR COUNT0
FIRST PUBLICATION YEAR1992
LATEST PUBLICATION YEAR2026
H-INDEX1
  • The Association Between Self-Reported Types of Toxic Exposures and Symptom Severity Among Gulf War Era Veterans

    Molly S Phan, Kara Winchell et al.•ARTICLE•Medical Care•2026•References: 18

    BACKGROUND: Gulf War illness is a chronic multisymptom illness impacting Veterans of the 1990-1991 Persian Gulf War. Toxic exposures are believed to be associated with the condition, but little is known about how multiple types of exposures can impact the disease. The aim of this study is to determine if a positive association exists between the multiplicity of exposure types and symptom severity score. METHODS: A cross-sectional survey design wa…

  • New (and Not so New) Directions in Evidence Synthesis Methods and Application in a Learning Health Care System

    Mark Helfand, Nicole Floyd et al.•ARTICLE•Medical Care•2019•References: 15

    Applying systematic review methods in the context of health systems is challenging. The very definition of a learning health care system as one that enables real-time and continuous improvement seems to underscore the mismatch with systematic review methods, in which a great deal of time is spent finding and sorting through studies, information is thrown into unwieldy tables, and evidence is often described as insufficient for decision-making.1 I…

  • Engagement in PCORnet Research Networks

    Open Access•Katherine K Kim, Katherine Kim et al.•ARTICLE•Medical Care•2018

    Efforts to engage patients and stakeholders are a ubiquitous element of Patient-Centered Outcomes Research Institute (PCORI)’s broader research program. The focus of that research is comparative effectiveness research that is built on what is important to patients. When PCORI began operations in 2011, it made an unwavering commitment to patient engagement while, at the same time, acknowledging that there was no proven recipe for doing so effectiv…

  • Decision flows into actions

    Open Access•Anne-Marike Schiffer, Mark Helfand et al.•ARTICLE•Nature Human Behaviour•2018

  • GRADE guidelines

    Open Access•Howard Balshem, Mark Helfand et al.•ARTICLE•Journal of Clinical Epidemiology•2011

  • Ten years of longitudinal research on U.S. adolescent sexual behavior

    Open Access•Melanie J Zimmer-Gembeck, Mark Helfand•ARTICLE•Developmental Review•2008

  • Incorporating Information About Cost-Effectiveness Into Evidence-Based Decision-Making

    Mark Helfand•ARTICLE•Medical Care•2005•References: 21

    RATIONALE: There is a pressing need for guidance on how to incorporate economic information into evidence-based decision-making. Such guidance should take account of the quality and relevance of economic evaluations. OBJECTIVE: To summarize lessons learned in integrating information from decision analyses and cost-effectiveness analyses. KEY ISSUES: Several methods used by the Evidence-Based Practice Centers (EPCs) to conduct systematic reviews a…

  • Practice Variation and the Risk of Low Birth Weight in a Public Prenatal Care Program

    Mark Helfand, Melanie J Zimmer-Gembeck•ARTICLE•Medical Care•1997•References: 22

    OBJECTIVES: Use of antepartum tests of fetal well-being is widespread even though effectiveness in preventing fetal damage or stillbirth has not been established. The study objective was to examine whether aggressive use of these tests might contribute to increased rates of other birth outcomes, including low birth weight (LBW). METHODS: A total of 3,235 low-income women receiving care from 28 clinic sites were studied. All women were eligible fo…

  • Low birthweight in a public prenatal care program

    Open Access•Melanie J Zimmer-Gembeck, Mark Helfand•ARTICLE•Social Science & Medicine•1996•Cited by: 12•References: 36

  • Effect of the Clinical Laboratory Improvement Amendments of 1988 (CLIA ??88) on the Incidence of Invasive Cervical Cancer

    Mark Helfand, Gerald T O??Connor et al.•ARTICLE•Medical Care•1992

    The Clinical Laboratory Improvement Act of 1988 (CLIA '88) mandates strict, new quality-control measures for laboratories that interpret cervical cytology smears. Proposed regulations include proficiency testing of cytotechnologists and remediation for technologists and laboratories that fail to meet proposed proficiency standards. Proponents of the new regulations argue that these measures will reduce deaths from cervical cancer by reducing the …

  • Low birthweight in a public prenatal care program

    Open Access•Melanie J Zimmer-Gembeck, Mark Helfand•ARTICLE•Social Science & Medicine•1996•Cited by: 12•References: 36

  • Effect of the Clinical Laboratory Improvement Amendments of 1988 (CLIA ??88) on the Incidence of Invasive Cervical Cancer

    Mark Helfand, Gerald T O??Connor et al.•ARTICLE•Medical Care•1992

    The Clinical Laboratory Improvement Act of 1988 (CLIA '88) mandates strict, new quality-control measures for laboratories that interpret cervical cytology smears. Proposed regulations include proficiency testing of cytotechnologists and remediation for technologists and laboratories that fail to meet proposed proficiency standards. Proponents of the new regulations argue that these measures will reduce deaths from cervical cancer by reducing the …

  • Low birthweight in a public prenatal care program

    Open Access•Melanie J Zimmer-Gembeck, Mark Helfand•ARTICLE•Social Science & Medicine•1996•Cited by: 12•References: 36

  • Practice Variation and the Risk of Low Birth Weight in a Public Prenatal Care Program

    Mark Helfand, Melanie J Zimmer-Gembeck•ARTICLE•Medical Care•1997•References: 22

    OBJECTIVES: Use of antepartum tests of fetal well-being is widespread even though effectiveness in preventing fetal damage or stillbirth has not been established. The study objective was to examine whether aggressive use of these tests might contribute to increased rates of other birth outcomes, including low birth weight (LBW). METHODS: A total of 3,235 low-income women receiving care from 28 clinic sites were studied. All women were eligible fo…

  • Incorporating Information About Cost-Effectiveness Into Evidence-Based Decision-Making

    Mark Helfand•ARTICLE•Medical Care•2005•References: 21

    RATIONALE: There is a pressing need for guidance on how to incorporate economic information into evidence-based decision-making. Such guidance should take account of the quality and relevance of economic evaluations. OBJECTIVE: To summarize lessons learned in integrating information from decision analyses and cost-effectiveness analyses. KEY ISSUES: Several methods used by the Evidence-Based Practice Centers (EPCs) to conduct systematic reviews a…

  • Ten years of longitudinal research on U.S. adolescent sexual behavior

    Open Access•Melanie J Zimmer-Gembeck, Mark Helfand•ARTICLE•Developmental Review•2008

  • GRADE guidelines

    Open Access•Howard Balshem, Mark Helfand et al.•ARTICLE•Journal of Clinical Epidemiology•2011

  • Engagement in PCORnet Research Networks

    Open Access•Katherine K Kim, Katherine Kim et al.•ARTICLE•Medical Care•2018

    Efforts to engage patients and stakeholders are a ubiquitous element of Patient-Centered Outcomes Research Institute (PCORI)’s broader research program. The focus of that research is comparative effectiveness research that is built on what is important to patients. When PCORI began operations in 2011, it made an unwavering commitment to patient engagement while, at the same time, acknowledging that there was no proven recipe for doing so effectiv…

  • Decision flows into actions

    Open Access•Anne-Marike Schiffer, Mark Helfand et al.•ARTICLE•Nature Human Behaviour•2018

  • New (and Not so New) Directions in Evidence Synthesis Methods and Application in a Learning Health Care System

    Mark Helfand, Nicole Floyd et al.•ARTICLE•Medical Care•2019•References: 15

    Applying systematic review methods in the context of health systems is challenging. The very definition of a learning health care system as one that enables real-time and continuous improvement seems to underscore the mismatch with systematic review methods, in which a great deal of time is spent finding and sorting through studies, information is thrown into unwieldy tables, and evidence is often described as insufficient for decision-making.1 I…

  • The Association Between Self-Reported Types of Toxic Exposures and Symptom Severity Among Gulf War Era Veterans

    Molly S Phan, Kara Winchell et al.•ARTICLE•Medical Care•2026•References: 18

    BACKGROUND: Gulf War illness is a chronic multisymptom illness impacting Veterans of the 1990-1991 Persian Gulf War. Toxic exposures are believed to be associated with the condition, but little is known about how multiple types of exposures can impact the disease. The aim of this study is to determine if a positive association exists between the multiplicity of exposure types and symptom severity score. METHODS: A cross-sectional survey design wa…

Medicine (8 works) · Psychology (4 works) · Alternative medicine (3 works) · Computer Science (3 works) · Engineering (3 works) · Health Systems, Economic Evaluations, Quality of Life (3 works) · Internal Medicine (3 works) · MEDLINE (3 works) · Population (3 works) · Anxiety (2 works)

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