Chakra Budhathoki
Biographic Data
| ID | 353040 |
|---|---|
| NAME | Chakra Budhathoki |
| GIVEN NAMES | Chakra |
| FAMILY NAME | Budhathoki |
| SIGNATURE | BUDHATHOKI C |
| AFFILIATIONS | Johns Hopkins University |
| ORCID | 0000-0002-1886-7847 |
| VERIFIED | Yes |
| TOTAL WORKS | 14 |
| TOTAL CITATIONS | 2 |
| AUTHOR COUNT | 14 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2014 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 1 |
Missed PrEP opportunities and vulnerability to HIV during rifampicin-resistant tuberculosis treatment in South Africa
Background: Adults receiving rifampicin-resistant TB (RR-TB) treatment have prolonged engagement with the health system, yet healthcare professionals frequently miss opportunities to promote HIV prevention-particularly pre-exposure prophylaxis (PrEP)-in high-burden settings. We examined HIV vulnerability, PrEP awareness and uptake, and HIV and sexually transmitted infection (STI) incidence among HIV-negative adults receiving RR-TB treatment. Meth…
What drives older adults’ acceptance of virtual humans? A conjoint and latent class analysis on virtual exercise coach attributes for a community-based exercise program
As an example of health-enhancing physical activities (HEPA), structured physical exercise is valuable in promoting healthy lifestyles among community-dwelling older adults. Technology-driven virtual coaches have the potential to enhance and improve exercise programs, but the preferences of the aging population were not previously explored. This study examined and analyzed the attributes and levels related to the acceptance of virtual coaches amo…
Disparities in Adverse and Positive Childhood Experiences Among Asian American Emerging Adults Ethnic Groups
The impact of a mixed reality technology-driven health enhancing physical activity program among community-dwelling older adults
Background Physical inactivity and a sedentary lifestyle among community-dwelling older adults poses a greater risk for progressive physical and cognitive decline. Mixed reality technology-driven health enhancing physical activities such as the use of virtual coaches provide an emerging and promising solution to support healthy lifestyle, but the impact has not been clearly understood. Methods and analysis An observational explanatory sequential …
Relationship between HIV viral suppression and multidrug resistant tuberculosis treatment outcomes
The impact of HIV viral suppression on multidrug resistant tuberculosis (MDR-TB) treatment outcomes among people with HIV (PWH) has not been clearly established. Using secondary data from a cluster-randomized clinical trial among people with MDR-TB in South Africa, we examined the effects of HIV viral suppression at MDR-TB treatment initiation and throughout treatment on MDR-TB outcomes among PWH using multinomial regression. This analysis includ…
Understanding human papillomavirus vaccine response and efficacy in people living with HIV
Coinfection with human papillomavirus (HPV) and HIV compounds the risks of developing cervical, anal, and HPV-associated oral neoplasia. Safe prophylactic vaccines are available to prevent HPV infections in people with HIV(PWH). Yet, vaccine efficacy and duration of protection remain questionable. Historically, the efficacy of vaccines has been suboptimal in PWH compared to people without HIV (PWoH).A systematic review of HPV vaccine trials in PW…
Critical research gaps in treating growth faltering in infants under 6 months
In 2020, 149.2 million children worldwide under 5 years suffered from stunting, and 45.4 million experienced wasting. Many infants are born already stunted, while others are at high risk for growth faltering early after birth. Growth faltering is linked to transgenerational impacts of poverty and marginalization. Few interventions address growth faltering in infants under 6 months, despite a likely increasing prevalence due to the negative global…
Cognitive dissonance in tuberculosis stigma
Background The Patient and Community Perspectives Towards Tuberculosis are the most common measure of tuberculosis (TB) stigma in sub-Saharan Africa. The instrument and its sub-scales (patient and community) have been quantitatively validated but have not undergone qualitative exploration in South Africa. Methods We explored whether the Patient Perspectives Towards Tuberculosis adequately represents stigma as experienced by people with TB in Sout…
Travel distance to rifampicin-resistant tuberculosis treatment and its impact on loss to follow-up
People living in KwaZulu-Natal and Eastern Cape travel long distances to receive RR-TB care, placing them at increased risk for LTFU. Policies that bring RR-TB treatment closer to patients, such as further decentralization to PHCs, are necessary to improve RR-TB outcomes
It All Depends
While the supporting role of families and friends has been widely recognized in cancer care, little data exist on how they influence patients' decisions regarding clinical trial participation, accounting for patients' decisional preferences. The goal of our study was to examine the process of clinical trial decision-making from the perspective of adults with cancer and their decision partners. Semi-structured interviews were conducted with 12 pat…
Female Genital Cutting
Health and academic consequences of sexual victimisation experiences among students in a university setting
The current study examines the association between multiple interpersonal violence victimization types experienced in a university setting and the consequences for each type. Students at a mid-Atlantic university ( n = 3977) completed a survey in 2015 assessing attitudes, experiences, consequences of (physical, behavioural, academic, mental), and university resources and reporting procedures for sexual assault, harassment, and intimate partner vi…
Associations of HIV testing with anxiety and stress within the African American church
The promotion of HIV testing among Black Americans is critical to reducing disproportionately high rates of HIV and AIDS. Anxiety and stress are often found to be associated with resistance to HIV testing. The Black Church, may have an important role in reducing stress and anxiety associated with HIV testing. In this cross-sectional survey-based study, we compared the responses of the congregants from two churches which offered testing and two wh…
The Relationship Between Sleep and Physical Function in Community-Dwelling Adults
More than 50% of community-dwelling adults have sleep complaints. Because aging is associated with decline in physical function, coexistent sleep difficulties may exacerbate functional decline. This pilot study explored the relationships between sleep, age, chronic disease burden, and physical function among 50 community-dwelling older adults. Findings revealed significant relationships between total sleep time and preclinical disability (r = -0.…
It All Depends
While the supporting role of families and friends has been widely recognized in cancer care, little data exist on how they influence patients' decisions regarding clinical trial participation, accounting for patients' decisional preferences. The goal of our study was to examine the process of clinical trial decision-making from the perspective of adults with cancer and their decision partners. Semi-structured interviews were conducted with 12 pat…
The Relationship Between Sleep and Physical Function in Community-Dwelling Adults
More than 50% of community-dwelling adults have sleep complaints. Because aging is associated with decline in physical function, coexistent sleep difficulties may exacerbate functional decline. This pilot study explored the relationships between sleep, age, chronic disease burden, and physical function among 50 community-dwelling older adults. Findings revealed significant relationships between total sleep time and preclinical disability (r = -0.…
Associations of HIV testing with anxiety and stress within the African American church
The promotion of HIV testing among Black Americans is critical to reducing disproportionately high rates of HIV and AIDS. Anxiety and stress are often found to be associated with resistance to HIV testing. The Black Church, may have an important role in reducing stress and anxiety associated with HIV testing. In this cross-sectional survey-based study, we compared the responses of the congregants from two churches which offered testing and two wh…
Female Genital Cutting
Health and academic consequences of sexual victimisation experiences among students in a university setting
The current study examines the association between multiple interpersonal violence victimization types experienced in a university setting and the consequences for each type. Students at a mid-Atlantic university ( n = 3977) completed a survey in 2015 assessing attitudes, experiences, consequences of (physical, behavioural, academic, mental), and university resources and reporting procedures for sexual assault, harassment, and intimate partner vi…
It All Depends
While the supporting role of families and friends has been widely recognized in cancer care, little data exist on how they influence patients' decisions regarding clinical trial participation, accounting for patients' decisional preferences. The goal of our study was to examine the process of clinical trial decision-making from the perspective of adults with cancer and their decision partners. Semi-structured interviews were conducted with 12 pat…
The impact of a mixed reality technology-driven health enhancing physical activity program among community-dwelling older adults
Background Physical inactivity and a sedentary lifestyle among community-dwelling older adults poses a greater risk for progressive physical and cognitive decline. Mixed reality technology-driven health enhancing physical activities such as the use of virtual coaches provide an emerging and promising solution to support healthy lifestyle, but the impact has not been clearly understood. Methods and analysis An observational explanatory sequential …
Relationship between HIV viral suppression and multidrug resistant tuberculosis treatment outcomes
The impact of HIV viral suppression on multidrug resistant tuberculosis (MDR-TB) treatment outcomes among people with HIV (PWH) has not been clearly established. Using secondary data from a cluster-randomized clinical trial among people with MDR-TB in South Africa, we examined the effects of HIV viral suppression at MDR-TB treatment initiation and throughout treatment on MDR-TB outcomes among PWH using multinomial regression. This analysis includ…
Understanding human papillomavirus vaccine response and efficacy in people living with HIV
Coinfection with human papillomavirus (HPV) and HIV compounds the risks of developing cervical, anal, and HPV-associated oral neoplasia. Safe prophylactic vaccines are available to prevent HPV infections in people with HIV(PWH). Yet, vaccine efficacy and duration of protection remain questionable. Historically, the efficacy of vaccines has been suboptimal in PWH compared to people without HIV (PWoH).A systematic review of HPV vaccine trials in PW…
Critical research gaps in treating growth faltering in infants under 6 months
In 2020, 149.2 million children worldwide under 5 years suffered from stunting, and 45.4 million experienced wasting. Many infants are born already stunted, while others are at high risk for growth faltering early after birth. Growth faltering is linked to transgenerational impacts of poverty and marginalization. Few interventions address growth faltering in infants under 6 months, despite a likely increasing prevalence due to the negative global…
Cognitive dissonance in tuberculosis stigma
Background The Patient and Community Perspectives Towards Tuberculosis are the most common measure of tuberculosis (TB) stigma in sub-Saharan Africa. The instrument and its sub-scales (patient and community) have been quantitatively validated but have not undergone qualitative exploration in South Africa. Methods We explored whether the Patient Perspectives Towards Tuberculosis adequately represents stigma as experienced by people with TB in Sout…
Travel distance to rifampicin-resistant tuberculosis treatment and its impact on loss to follow-up
People living in KwaZulu-Natal and Eastern Cape travel long distances to receive RR-TB care, placing them at increased risk for LTFU. Policies that bring RR-TB treatment closer to patients, such as further decentralization to PHCs, are necessary to improve RR-TB outcomes
What drives older adults’ acceptance of virtual humans? A conjoint and latent class analysis on virtual exercise coach attributes for a community-based exercise program
As an example of health-enhancing physical activities (HEPA), structured physical exercise is valuable in promoting healthy lifestyles among community-dwelling older adults. Technology-driven virtual coaches have the potential to enhance and improve exercise programs, but the preferences of the aging population were not previously explored. This study examined and analyzed the attributes and levels related to the acceptance of virtual coaches amo…
Disparities in Adverse and Positive Childhood Experiences Among Asian American Emerging Adults Ethnic Groups
Missed PrEP opportunities and vulnerability to HIV during rifampicin-resistant tuberculosis treatment in South Africa
Background: Adults receiving rifampicin-resistant TB (RR-TB) treatment have prolonged engagement with the health system, yet healthcare professionals frequently miss opportunities to promote HIV prevention-particularly pre-exposure prophylaxis (PrEP)-in high-burden settings. We examined HIV vulnerability, PrEP awareness and uptake, and HIV and sexually transmitted infection (STI) incidence among HIV-negative adults receiving RR-TB treatment. Meth…
Medicine (11 works) · Psychology (8 works) · Internal Medicine (6 works) · Gerontology (4 works) · Psychiatry (4 works) · Tuberculosis (4 works) · Tuberculosis Research and Epidemiology (4 works) · Clinical Psychology (3 works) · Demography (3 works) · Family medicine (3 works)