Jeffrey Rogers
Biographic Data
| ID | 3693968 |
|---|---|
| NAME | Jeffrey Rogers |
| GIVEN NAMES | Jeffrey |
| FAMILY NAME | Rogers |
| SIGNATURE | ROGERS J |
| AFFILIATIONS | Texas Biomedical Research Institute |
| ORCID | 0000-0002-7374-6490 |
| VERIFIED | Yes |
| TOTAL WORKS | 40 |
| TOTAL CITATIONS | 147 |
| AUTHOR COUNT | 40 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1990 |
| LATEST PUBLICATION YEAR | 2021 |
| H-INDEX | 6 |
Variation in predicted Covid‐19 risk among lemurs and lorises
The novel coronavirus SARS‐CoV‐2, which in humans leads to the disease COVID‐19, has caused global disruption and more than 2 million fatalities since it first emerged in late 2019. As we write, infection rates are at their highest point globally and are rising extremely rapidly in some areas due to more infectious variants. The primary target of SARS‐CoV‐2 is the cellular receptor angiotensin‐converting enzyme‐2 (ACE2). Recent sequence analyses …
Comparison of vitamin D metabolites in wild and captive baboons
Vitamin D adequacy is essential for multiple physiologic processes. With limited exposure to sunlight for vitamin D 3 synthesis, captive primates are supplemented with vitamin D 3 (cholecalciferol). Vitamin D metabolite data from wild primates living indigenously could suggest optimum levels. The purpose of this study was to: 1) to explore whether baboons, a speciose genus whose members have significant exposed skin, coat color variation and wide…
The behavioral genetics of nonhuman primates
The complexity and diversity of primate behavior have long attracted the attention of ethologists, psychologists, behavioral ecologists, and neuroscientists. Recent studies have advanced our understanding of the nature of genetic influences on differences in behavior among individuals within species. A number of analyses have focused on the genetic analysis of behavioral reactions to specific experimental tests, providing estimates of the degree …
Additive genetic variation in the craniofacial skeleton of baboons (genus Papio ) and its relationship to body and cranial size
Objectives Determining the genetic architecture of quantitative traits and genetic correlations among them is important for understanding morphological evolution patterns. We address two questions regarding papionin evolution: (1) what effect do body and cranial size, age, and sex have on phenotypic ( V P ) and additive genetic ( V A ) variation in baboon crania, and (2) how might additive genetic correlations between craniofacial traits and body…
The ticking clock of Cayo Santiago macaques and its implications for understanding human circadian rhythm disorders
The circadian clock disorders in humans remain poorly understood. However, their impact on the development and progression of major human conditions, from cancer to insomnia, metabolic or mental illness becomes increasingly apparent. Addressing human circadian disorders in animal models is, in part, complicated by inverse temporal relationship between the core clock and specific physiological or behavioral processes in diurnal and nocturnal anima…
Nuclear DNA Polymorphisms in Hominoids and Cercopithecoids
Why primate models matter
Research involving nonhuman primates (NHPs) has played a vital role in many of the medical and scientific advances of the past century. NHPs are used because of their similarity to humans in physiology, neuroanatomy, reproduction, development, cognition, and social complexity-yet it is these very similarities that make the use of NHPs in biomedical research a considered decision. As primate researchers, we feel an obligation and responsibility to…
Development and validation of a SNP‐based assay for inferring the genetic ancestry of rhesus macaques ( Macaca mulatta )
Rhesus macaques (Macaca mulatta) are an important primate model species in several areas of biomedical research. The wide geographic distribution of this species has led to significant genetic differentiation among local and regional populations. These regional differences can be important factors in the selection of the most appropriate subjects for particular research studies, as animals from different populations can respond differently to the…
Quantitative Genetics of Response to Novelty and Other Stimuli by Infant Rhesus Macaques (Macaca mulatta) Across Three Behavioral Assessments
Further evidence for phenotypic signatures of hybridization in descendant baboon populations
Genetic and environmental contributions to variation in baboon cranial morphology
The development, function, and integration of morphological characteristics are all hypothesized to influence the utility of traits for phylogenetic reconstruction by affecting the way in which morphological characteristics evolve. We use a baboon model to test the hypotheses about phenotypic and quantitative genetic variation of traits in the cranium that bear on a phenotype's propensity to evolve. We test the hypotheses that: 1) individual trai…
A Celebration of Clifford Jolly's Contribution to Biological Anthropology
Polymorphic microsatellite loci for the common marmoset ( Callithrix jacchus ) designed using a cost‐ and time‐efficient method
We describe a cost‐ and time‐efficient method for designing new microsatellite markers in any species with substantial genomic DNA sequence data available. Using this technique, we report 14 new polymorphic dinucleotide microsatellite loci isolated from the common marmoset. The relative yield of new polymorphisms was higher with less labor than described in previous marmoset studies. Of 20 loci initially evaluated, 14 were polymorphic and amplifi…
Trisomy 17 in a baboon ( Papio hamadryas ) with polydactyly, patent foramen ovale and pyelectasis
Trisomy 13 in humans is the third most common autosomal abnormality at birth, after trisomy 21 and trisomy 18. It has a reported incidence of between 1:5,000 and 1:30,000 live births. It is associated with multiple abnormalities, many of which shorten lifespan. We describe here the first reported case of a baboon ( Papio hamadryas ) with trisomy of chromosome 17, which is homologous to human chromosome 13. The trisomic infant was born to a consan…
Microsatellite markers for standardized genetic management of captive colonies of rhesus macaques (Macaca mulatta)
To preserve genetic variability and minimize genetic subdivision among captive Macaca mulatta at each of the U.S. National Institutes of Health (NIH)-sponsored regional research colonies, the genetic structure of each colony must be characterized. To compare population genetic and demographic parameters across colonies and generations, one standard panel of highly informative genetic markers is required. We assembled a core marker set of four mul…
Identifying the morphological signatures of hybridization in primate and human evolution
Contributed Abstracts
Over the past five years, there has been rapid progress in the study of primate genomes. The complete sequencing of the human genome has been quickly followed by draft sequencing of the chimpanzee (Pan troglodytes) genome. Projects are currently underway to produce whole genome sequence assemblies for rhesus macaques (Macaca mulatta) and orangutans (Pongo pygmaeus). It is likely that other primate genomes will also be sequenced to a modest level …
A panel of 20 highly variable microsatellite polymorphisms in rhesus macaques (Macaca mulatta) selected for pedigree or population genetic analysis
This paper reports 20 new microsatellite loci that are highly polymorphic in rhesus macaques (Macaca mulatta). We screened known human microsatellite loci to identify markers that are polymorphic in rhesus macaques, and then selected specific loci that show substantial levels of heterozygosity and robust, reliable amplification. The 20 loci reported here were chosen to include one highly informative microsatellite from each rhesus monkey autosoma…
Mitochondrial phylogeny and systematics of baboons ( Papio )
Baboons ( Papio , s.s.) comprise a series of parapatric allotaxa (subspecies or closely related species) widely distributed in sub‐Saharan Africa. Despite extensive studies of their ecology, morphology, and behavior, disagreement about their phylogenetic relationships continues, as expressed in the current coexistence of at least three major, competing taxonomic treatments. To help resolve this situation, we sequenced ∼900 bases of mitochondrial …
Effectiveness of human microsatellite loci for assessing paternity in a captive colony of vervets ( Chlorocebus aethiops sabaeus )
Microsatellite polymorphisms are playing an increasingly vital role in primatological research, and are particularly useful for paternity exclusion in both wild and captive populations. Although vervet monkeys ( Chlorocebus aethiops ) are commonly studied in both settings, few previous studies have utilized microsatellite markers for assessing genetic variation in this species. In a pilot project to assess paternity in the UCLA‐VA Vervet Monkey R…
Individual variation in the growth of captive infant gorillas
Serial anthropometric data were obtained during the first year of life of six nursery‐reared infant gorillas in the Columbus (Ohio) Zoo. Two of the infants are likely to be monozygotic twins as determined by DNA analysis. Growth curves were fitted to serial measures of cephalo‐thoracic‐abdominal length, arm length, leg length, head circumference, upper arm circumference, and weight from each gorilla, to describe individual patterns of variation i…
A Quantitative Trait Locus Influencing Activin-to-Estrogen Ratio in Pedigreed Baboons Maps to a Region Homologous to Human Chromosome 19
Activin is a multifunctional hormone playing a major role in the regulation of reproduction and growth and development. We performed a genomewide scan using multipoint linkage analysis implemented in a general pedigree-based variance component approach to identify genes with measurable effects on variation in the activin-to-estrogen ratio in baboons. A microsatellite polymorphism, D19S714, which maps to human chromosome 19p13.2, showed marginal e…
Nineteen new microsatellite DNA polymorphisms in pigtailed macaques (Macaca nemestrina)
Microsatellite polymorphisms in Bolivian squirrel monkeys (Saimiri boliviensis)
Two different approaches were used to identify new microsatellite polymorphisms among captive Bolivian squirrel monkeys (Saimiri boliviensis). In the first case, PCR primers for published human microsatellite loci were screened using genomic DNA from squirrel monkeys. Six polymorphic loci were identified using DNA samples from 19 unrelated individuals. The average heterozygosity among these six loci is 0.73. In the second set of experiments, a DN…
Microsatellite polymorphisms in Bolivian squirrel monkeys (Saimiri boliviensis)
Two different approaches were used to identify new microsatellite polymorphisms among captive Bolivian squirrel monkeys (Saimiri boliviensis). In the first case, PCR primers for published human microsatellite loci were screened using genomic DNA from squirrel monkeys. Six polymorphic loci were identified using DNA samples from 19 unrelated individuals. The average heterozygosity among these six loci is 0.73. In the second set of experiments, a DN…
Identifying the morphological signatures of hybridization in primate and human evolution
Mitochondrial phylogeny and systematics of baboons ( Papio )
Baboons ( Papio , s.s.) comprise a series of parapatric allotaxa (subspecies or closely related species) widely distributed in sub‐Saharan Africa. Despite extensive studies of their ecology, morphology, and behavior, disagreement about their phylogenetic relationships continues, as expressed in the current coexistence of at least three major, competing taxonomic treatments. To help resolve this situation, we sequenced ∼900 bases of mitochondrial …
Further evidence for phenotypic signatures of hybridization in descendant baboon populations
Genetic and environmental contributions to variation in baboon cranial morphology
The development, function, and integration of morphological characteristics are all hypothesized to influence the utility of traits for phylogenetic reconstruction by affecting the way in which morphological characteristics evolve. We use a baboon model to test the hypotheses about phenotypic and quantitative genetic variation of traits in the cranium that bear on a phenotype's propensity to evolve. We test the hypotheses that: 1) individual trai…
The phylogenetic relationships among Homo, Pan and Gorilla
Additive genetic variation in the craniofacial skeleton of baboons (genus Papio ) and its relationship to body and cranial size
Objectives Determining the genetic architecture of quantitative traits and genetic correlations among them is important for understanding morphological evolution patterns. We address two questions regarding papionin evolution: (1) what effect do body and cranial size, age, and sex have on phenotypic ( V P ) and additive genetic ( V A ) variation in baboon crania, and (2) how might additive genetic correlations between craniofacial traits and body…
The behavioral genetics of nonhuman primates
The complexity and diversity of primate behavior have long attracted the attention of ethologists, psychologists, behavioral ecologists, and neuroscientists. Recent studies have advanced our understanding of the nature of genetic influences on differences in behavior among individuals within species. A number of analyses have focused on the genetic analysis of behavioral reactions to specific experimental tests, providing estimates of the degree …
Levels of the genealogical hierarchy and the problem of hominoid phylogeny
Molecular data are widely used to reconstruct phylogenetic relationships among species, and these phylogenies are often used as the basis for inferences about the history of evolutionary change in other nonmolecular characters. This approach is an appropriate and powerful one in many circumstances. But when several lineages diverge over a relatively short period of time, the assumption that a molecular (gene) tree will always be a valid basis for…
Quantitative Genetics of Response to Novelty and Other Stimuli by Infant Rhesus Macaques (Macaca mulatta) Across Three Behavioral Assessments
Individual variation in the growth of captive infant gorillas
Serial anthropometric data were obtained during the first year of life of six nursery‐reared infant gorillas in the Columbus (Ohio) Zoo. Two of the infants are likely to be monozygotic twins as determined by DNA analysis. Growth curves were fitted to serial measures of cephalo‐thoracic‐abdominal length, arm length, leg length, head circumference, upper arm circumference, and weight from each gorilla, to describe individual patterns of variation i…
Microsatellite Variation in Two Populations of Free-Ranging Yellow Baboons (Papio hamadryas cynocephalus)
Mammalian dispersal patterns
Secondary sex ratio and maternal dominance rank among wild yellow baboons ( Papio cynocephalus ) of Mikumi National Park, Tanzania
The Trivers and Willard model predicts that offspring of dominant mothers will be biased toward males and offspring of subordinate mothers towards females, whereas a local‐resource‐competition hypothesis predicts the reverse. Available data bearing upon these alternative predictions are inconsistent. It has been suggested that the local‐resource‐competition hypothesis will predominate when resources are scarce, and the Trivers‐Willard hypothesis …
Variability in nuclear DNA among nonhuman primates
Nuclear DNA clones and sequence information derived from human genetic analyses were used to detect and characterize intra‐ and inter‐species DNA variation at several nuclear loci in hominoids and cercopithecoids. Restriction fragment length polymorphisms were found at five loci among captive rhesus monkeys. Cross‐species polymerase chain reaction (PCR) amplification detected an insertion within the beta‐globin gene cluster in hylobatids. The com…
Nuclear DNA polymorphisms in a wild population of yellow baboons ( Papio hamadryas cynocephalus ) from Mikumi National Park, Tanzania
Yellow baboons ( Papio hamadryas cynocephalus ) from Mikumi National Park, Tanzania were studied for polymorphisms in nuclear DNA. The study population consists of four social groups that inhabit overlapping home ranges and exchange males. As a result, these groups are considered to be members of a single interbreeding population. Human DNA clones were used as probes to screen five loci (AT3, REN, HEXB, VIM, and APOB) for restriction fragment len…
Obituary
The phylogenetic relationships among Homo, Pan and Gorilla
Levels of the genealogical hierarchy and the problem of hominoid phylogeny
Molecular data are widely used to reconstruct phylogenetic relationships among species, and these phylogenies are often used as the basis for inferences about the history of evolutionary change in other nonmolecular characters. This approach is an appropriate and powerful one in many circumstances. But when several lineages diverge over a relatively short period of time, the assumption that a molecular (gene) tree will always be a valid basis for…
When is ancient polymorphism a potential problem for molecular phylogenetics
Nucleotide polymorphism, effective population size, and dispersal distances in the yellow baboons (Papio hamadryas cynocephalus) of Mikumi National Park, Tanzania
We investigated genetic variability and population structure in a natural population of yellow baboons (Papio hamadryas cynocephalus) from Mikumi National Park, Tanzania. The amount of nuclear DNA polymorphism in a random sample of animals from four social groups was estimated by using Southern blotting to detect restriction fragment length polymorphisms in five nuclear autosomal loci. The average nucleotide heterozygosity was estimated to be 0.0…
Interspecific variation at the Y‐linked RPS4Y locus in hominoids
Interspecific variation at the Y‐linked RPS4Y locus in hominoids
Within- and between-species variation in restriction endonuclease recognition sites was examined at the Y-linked RPS4Y locus of six hominoid species: human (Homo sapiens), gorilla (Gorilla gorilla), chimpanzee (Pan troglodytes), bonobo (Pan paniscus), orangutan (Pongo pygmaeus), and gibbon (Hylobates lar). RPS4Y is an expressed gene that maps to the non-recombining region of the Y chromosome. An approximately 1,490 base pair fragment of the RPS4Y…
Teratoma with trisomy 16 in a baboon (Papio hamadryas)
A teratoma was found during a planned cesarean section in a 10-year-old primigravida baboon. This teratoma had a female sex chromosome complement and trisomy for chromosome 16. This is the first report of a teratoma in a baboon and the first report of a chromosomal abnormality in a nonhuman primate teratoma. It is also the first case in a nonhuman primate to address the mechanism of origin. Through the use of genetic markers from human chromosome…
Microsatellite Variation in Two Populations of Free-Ranging Yellow Baboons (Papio hamadryas cynocephalus)
Microsatellite polymorphisms in Bolivian squirrel monkeys (Saimiri boliviensis)
Two different approaches were used to identify new microsatellite polymorphisms among captive Bolivian squirrel monkeys (Saimiri boliviensis). In the first case, PCR primers for published human microsatellite loci were screened using genomic DNA from squirrel monkeys. Six polymorphic loci were identified using DNA samples from 19 unrelated individuals. The average heterozygosity among these six loci is 0.73. In the second set of experiments, a DN…
Microsatellite polymorphisms in Bolivian squirrel monkeys (Saimiri boliviensis)
Two different approaches were used to identify new microsatellite polymorphisms among captive Bolivian squirrel monkeys (Saimiri boliviensis). In the first case, PCR primers for published human microsatellite loci were screened using genomic DNA from squirrel monkeys. Six polymorphic loci were identified using DNA samples from 19 unrelated individuals. The average heterozygosity among these six loci is 0.73. In the second set of experiments, a DN…
Cytogenetic and fertility studies of a rheboon, rhesus macaque (Macaca mulatta) baboon (Papio hamadryas) cross
Historically, two different numbering systems have been used to describe the baboon and macaque karyotypes. However, G-banding studies and, more recently, fluorescence in situ hybridization results have shown that the two karyotypes are virtually identical. To confirm this hypothesis, cytogenetic analysis of an unusual animal, a rheboon, was undertaken. The rheboon reported here, an 18-year-old male, is the only long-term survivor of 26 pregnanci…
Cytogenetic and fertility studies of a rheboon, rhesus macaque (Macaca mulatta) × baboon (Papio hamadryas) cross
Historically, two different numbering systems have been used to describe the baboon and macaque karyotypes. However, G-banding studies and, more recently, fluorescence in situ hybridization results have shown that the two karyotypes are virtually identical. To confirm this hypothesis, cytogenetic analysis of an unusual animal, a rheboon, was undertaken. The rheboon reported here, an 18-year-old male, is the only long-term survivor of 26 pregnanci…
Nineteen new microsatellite DNA polymorphisms in pigtailed macaques (Macaca nemestrina)
Individual variation in the growth of captive infant gorillas
Serial anthropometric data were obtained during the first year of life of six nursery‐reared infant gorillas in the Columbus (Ohio) Zoo. Two of the infants are likely to be monozygotic twins as determined by DNA analysis. Growth curves were fitted to serial measures of cephalo‐thoracic‐abdominal length, arm length, leg length, head circumference, upper arm circumference, and weight from each gorilla, to describe individual patterns of variation i…
A Quantitative Trait Locus Influencing Activin-to-Estrogen Ratio in Pedigreed Baboons Maps to a Region Homologous to Human Chromosome 19
Activin is a multifunctional hormone playing a major role in the regulation of reproduction and growth and development. We performed a genomewide scan using multipoint linkage analysis implemented in a general pedigree-based variance component approach to identify genes with measurable effects on variation in the activin-to-estrogen ratio in baboons. A microsatellite polymorphism, D19S714, which maps to human chromosome 19p13.2, showed marginal e…
Effectiveness of human microsatellite loci for assessing paternity in a captive colony of vervets ( Chlorocebus aethiops sabaeus )
Microsatellite polymorphisms are playing an increasingly vital role in primatological research, and are particularly useful for paternity exclusion in both wild and captive populations. Although vervet monkeys ( Chlorocebus aethiops ) are commonly studied in both settings, few previous studies have utilized microsatellite markers for assessing genetic variation in this species. In a pilot project to assess paternity in the UCLA‐VA Vervet Monkey R…
Mitochondrial phylogeny and systematics of baboons ( Papio )
Baboons ( Papio , s.s.) comprise a series of parapatric allotaxa (subspecies or closely related species) widely distributed in sub‐Saharan Africa. Despite extensive studies of their ecology, morphology, and behavior, disagreement about their phylogenetic relationships continues, as expressed in the current coexistence of at least three major, competing taxonomic treatments. To help resolve this situation, we sequenced ∼900 bases of mitochondrial …
Contributed Abstracts
Over the past five years, there has been rapid progress in the study of primate genomes. The complete sequencing of the human genome has been quickly followed by draft sequencing of the chimpanzee (Pan troglodytes) genome. Projects are currently underway to produce whole genome sequence assemblies for rhesus macaques (Macaca mulatta) and orangutans (Pongo pygmaeus). It is likely that other primate genomes will also be sequenced to a modest level …
A panel of 20 highly variable microsatellite polymorphisms in rhesus macaques (Macaca mulatta) selected for pedigree or population genetic analysis
This paper reports 20 new microsatellite loci that are highly polymorphic in rhesus macaques (Macaca mulatta). We screened known human microsatellite loci to identify markers that are polymorphic in rhesus macaques, and then selected specific loci that show substantial levels of heterozygosity and robust, reliable amplification. The 20 loci reported here were chosen to include one highly informative microsatellite from each rhesus monkey autosoma…
Microsatellite markers for standardized genetic management of captive colonies of rhesus macaques (Macaca mulatta)
To preserve genetic variability and minimize genetic subdivision among captive Macaca mulatta at each of the U.S. National Institutes of Health (NIH)-sponsored regional research colonies, the genetic structure of each colony must be characterized. To compare population genetic and demographic parameters across colonies and generations, one standard panel of highly informative genetic markers is required. We assembled a core marker set of four mul…
Biology (34 works) · Primate Behavior and Ecology (24 works) · Evolutionary biology (22 works) · Gene (18 works) · Genetics (18 works) · Genetics (18 works) · Ecology (14 works) · Zoology (14 works) · Population (11 works) · Allele (9 works)