Glenda Gray

Biographic Data

ID3918031
NAMEGlenda Gray
GIVEN NAMESGlenda
FAMILY NAMEGray
SIGNATUREGRAY G
AFFILIATIONSSouth African Medical Research Council
ORCID0000-0003-4649-1477
VERIFIEDYes
TOTAL WORKS54
TOTAL CITATIONS102
AUTHOR COUNT54
EDITOR COUNT0
FIRST PUBLICATION YEAR2004
LATEST PUBLICATION YEAR2025
H-INDEX3

  • Alvac-prime and monomeric gp120 protein boost induces distinct HIV-1 specific humoral and cellular responses compared with adenovirus-prime and trimeric gp140 protein boost

    Open AccessLeigh H Fisher, Erica Lazarus et al.ARTICLEPLOS Global Public Health2025

    Although clade-specific and cross-clade mosaic prime–boost HIV-1 vaccine regimens were advanced to the HVTN 702 and HVTN 705 efficacy trials, neither regimen prevented HIV acquisition. The respective Phase 1/2a studies, HVTN 100 (NCT02404311) and HVTN 117/HPX2004 (NCT02788045), provided rich immunological data, including previously identified correlates of risk, for comparing immune responses elicited by these vaccine regimens over time. We analy…

  • Safety and immunogenicity of booster vaccination and fractional dosing with Ad26.COV2.S or BNT162b2 in Ad26.COV2.S-vaccinated participants

    Open AccessCatherine Riou, Jinal N Bhiman et al.ARTICLEPLOS Global Public Health2024

    We report the safety and immunogenicity of fractional and full dose Ad26.COV2.S and BNT162b2 in an open label phase 2 trial of participants previously vaccinated with a single dose of Ad26.COV2.S, with 91.4% showing evidence of previous SARS-CoV-2 infection. A total of 286 adults (with or without HIV) were enrolled >4 months after an Ad26.COV2.S prime and randomized 1:1:1:1 to receive either a full or half-dose booster of Ad26.COV2.S or BNT162b2 …

  • Safety, effectiveness and immunogenicity of heterologous mRNA-1273 boost after prime with Ad26.COV2.S among healthcare workers in South Africa

    Open AccessNigel Garrett, Tarylee Reddy et al.ARTICLEPLOS Global Public Health2024

    Limited studies have been conducted on the safety and effectiveness of heterologous COVID-19 vaccine boosting in lower income settings, especially those with high-HIV prevalence., The Sisonke Heterologous mRNA-1273 boost after prime with Ad26.COV2.S (SHERPA) trial evaluated a mRNA-1273 boost after Ad26.COV2.S priming in South Africa. SHERPA was a single-arm, open-label, phase 3 study nested in the Sisonke implementation trial of 500000 healthcare…

  • Sex work and young women

    Open AccessMinja Milovanovic, Rachel Jewkes et al.ARTICLEAIDS Care2023

    Adolescent girls and young women (AGYW) engaging in sex-for-money transactions are at risk of HIV infection. A better understanding of the demographic, socio-economic factors and risks of HIV acquisition is required to guide appropriate public health interventions targeting young sex workers in South Africa. A cross-sectional survey of Female Sex Workers (FSWs), using a chain referral sampling method, was conducted across 12 sites in South Africa…

  • Risk Factors Associated with HIV Acquisition in Males Participating in HIV Vaccine Efficacy Trials in South Africa

    Open AccessMookho Malahleha, Fatima Laher et al.ARTICLEAIDS and Behavior2023

    In South Africa, HIV acquisition risk has been studied less in people assigned male at birth. We studied the associations between risk behaviors, clinical features and HIV incidence amongst males in two South African HIV preventive vaccine efficacy trials. We used Cox proportional hazards models to test for associations between demographics, sexual behaviors, clinical variables and HIV acquisition among males followed in the HVTN 503 (n = 219) an…

  • Understanding drivers of female sex workers’ experiences of external/enacted and internalised stigma

    Open AccessRachel Jewkes, Minja Milovanovic et al.ARTICLECulture Health & Sexuality2023

    To deepen our understanding of sex work stigma, and to its drivers and their interrelation, we conducted an analysis using structural equation modelling of the South African National Sex Worker Survey. We enrolled 3005 women in sex work using multi-stage sampling across all South Africa's provinces. Experience of external/enacted and internalised stigma was widespread. Non-partner rape, intimate partner violence and partner controlling behaviour …

  • Health system response to preventing mother-to-child transmission of HIV policy changes in Zambia

    Open AccessJonathan Mwanza, Mary Kawonga et al.ARTICLEGlobal Health Action2022

    BACKGROUND: Zambia is focusing on attaining HIV epidemic control by 2021, including eliminating Mother to Child Transmission (eMTCT) of HIV. However, there is little evidence to understand frontline healthcare workers' experience with the policy changes and the readiness of different health system elements to contribute to this goal. OBJECTIVE: To understand frontline healthcare workers' experience of preventing mother-to-child transmission (PMTC…

  • Gender, Power, and Health

    Open AccessKalysha Closson, Jane Ndungu et al.ARTICLETrauma Violence & Abuse2022

    Gender inequity, including low sexual relationship power (SRP), is an important determinant of intimate partner violence (IPV) and negative sexual, reproductive, and mental health. Different versions of the Sexual Relationship Power Scale (SRPS) are commonly used within youth studies to examine how gender inequities, including controlling behaviors, in heterosexual relationships impact the lives of young people in sub-Saharan Africa. This review …

  • The HIV Cascade of Care and Service Utilisation at Sex Work Programmes Among Female Sex Workers in South Africa

    Open AccessMaya Jaffer, Nicola Christofides et al.ARTICLEAIDS and Behavior2022

    Female sex workers (FSWs) in South Africa experience a uniquely high prevalence of HIV. We describe the HIV cascade of care (CoC) in FSWs in South Africa, and explored service utilisation at sex work programmes. A cross-sectional, study enrolled FSWs across 12 sites in South Africa. Participants were recruited using chain-referral method. Inclusion criteria: ≥ 18 years, cis-gender female, sold/transacted in sex, HIV positive. 1862 HIV positive FS…

  • Examining the Relationship Between Psychosocial Factors with Knowledge of HIV-Positive Status and Antiretroviral Therapy Exposure Among Adolescent Girls and Young Women Living with HIV in South Africa

    Open AccessJanan Dietrich, Kim Jonas et al.ARTICLEAIDS and Behavior2022

  • Sexual IPV and non-partner rape of female sex workers

    Open AccessRachel Jewkes, Kennedy Otwombe et al.ARTICLESSM - Mental Health2021

    BACKGROUND: Globally female sex workers (FSWs) are vulnerable to violence from intimate partners, police and clients due to stigma and criminalisation. In this paper we describe South African FSWs' exposure to violence and factors associated with having been raped in the past year. METHODS: We conducted a multi-stage, community-centric, cross-sectional survey of 3005 FSWs linked to sex worker programmes in 12 sites across all nine provinces that …

  • High cellphone use associated with greater risk of depression among young women aged 15–24 years in Soweto and Durban, South Africa

    Open AccessJanan Dietrich, Kennedy Otwombe et al.ARTICLEGlobal Health Action2021

    BACKGROUND: The ubiquity of cellular phone (cellphone) use in young people's daily lives has emerged as a priority area of concern for youth mental health. OBJECTIVE: This study measured the prevalence of depression and its association with high cellphone use among youth in Soweto and Durban, South Africa. METHODS: We analysed cross-sectional, baseline survey data among youth aged 16-24 who participated in a dual-site cohort study, 'AYAZAZI', con…

  • Community-led cross-sectional study of social and employment circumstances, HIV and associated factors amongst female sex workers in South Africa

    Open AccessMinja Milovanovic, Rachel Jewkes et al.ARTICLEGlobal Health Action2021

    BACKGROUND: In South Africa, female sex workers (FSWs) are perceived to play a pivotal role in the country's HIV epidemic. Understanding their health status and risk factors for adverse health outcomes is foundational for developing evidence-based health care for this population. OBJECTIVE: Describe the methodology used to successfully implement a community-led study of social and employment circumstances, HIV and associated factors amongst FSWs …

  • Evolution of prevention of mother to child transmission of HIV policy in Zambia

    Open AccessJonathan Mwanza, Mary Kawonga et al.ARTICLEGlobal Public Health2021

    The Prevention of Mother-to-child Transmission (PMTCT) of HIV program in Zambia has undergone several policy iterations over the past 10 years. This qualitative study aimed to contribute towards addressing this knowledge gap by analysing the evolution and actors' influence during the policy process using the Walt and Gilson policy triangle as our evaluation framework. Document review and key informant interviews with policy makers were undertaken…

  • Spatial and Temporal Trends of Sars-CoV-2 RNA from Wastewater Treatment Plants over 6 Weeks in Cape Town, South Africa

    Open AccessRenée Street, Angela Mathee et al.ARTICLEInternational Journal of…2021

    Recent scientific trends have revealed that the collection and analysis of data on the occurrence and fate of SARS-CoV-2 in wastewater may serve as an early warning system for COVID-19. In South Africa, the first COVID-19 epicenter emerged in the Western Cape Province. The City of Cape Town, located in the Western Cape Province, has approximately 4 million inhabitants. This study reports on the monitoring of SARS-CoV-2 RNA in the wastewater of th…

  • Understanding Repeat Positive HIV Testing in South Africa Under Changing Treatment Guidelines

    Open AccessMaria F Nardell, Bethany Hedt-Gauthier et al.ARTICLEAIDS and Behavior2021

  • Covid-19 in Africa

    Open AccessMatthew Chersich, Glenda Gray et al.ARTICLEGlobalization and Health2020

    Medical staff caring for COVID-19 patients face mental stress, physical exhaustion, separation from families, stigma, and the pain of losing patients and colleagues. Many of them have acquired SARS-CoV-2 and some have died. In Africa, where the pandemic is escalating, there are major gaps in response capacity, especially in human resources and protective equipment. We examine these challenges and propose interventions to protect healthcare worker…

  • Willingness to use HIV prevention methods among vaccine efficacy trial participants in Soweto, South Africa

    Open AccessFatima Laher, Taibat Salami et al.ARTICLEBMC Public Health2020

    The participants' candour about barriers to condom and daily oral pre-exposure prophylaxis (PrEP) use, and expressed preferences for long-lasting, discreet, lifestyle-friendly methods reveal a gap in the biomedical prevention market aiming to reduce sexually acquired HIV in South Africa. Product developers should consider long-acting injectable formulations, such as vaccines, passive antibodies and chemoprophylaxis, for HIV prevention technologie…

  • Gender differences in prevalence and correlates of high sexual self-efficacy among adolescents in Soweto, South Africa

    Kalysha Closson, Janan Dietrich et al.ARTICLEAIDS Care2018

    Sexual self-efficacy (SSE) - one's confidence in their ability to perform given sexual behaviours, has been shown to predict adolescents' HIV-prevention practices (e.g., Condom use). Few studies within sub-Saharan Africa, where HIV incidence and prevalence disproportionately affects young women, have examined gendered differences in SSE. We used multivariable logistic regression to identify correlates of high-SSE separately among adolescent men a…

  • Mobile Phone Questionnaires for Sexual Risk Data Collection Among Young Women in Soweto, South Africa

    Open Accessfor the HVTN study team, Janan Dietrich et al.ARTICLEAIDS and Behavior2018

  • It Was Not My Aim to Sleep There”

    Open AccessF Scorgie, Jonathan Stadler et al.ARTICLEAIDS and Behavior2018

  • Sexual Self-Efficacy and Gender

    Kalysha Closson, Janan Dietrich et al.ARTICLEThe Journal of Sex Research2018

    Sexual self-efficacy (SSE), one's perceived control of or confidence in the ability to perform a given sexual outcome, predicts sexual behavior; however, important questions remain regarding whether gender modifies observed associations. In a comprehensive review of peer-reviewed HIV-prevention literature focusing on youth (ages 10 to 25) in sub-Saharan Africa, we measured and assessed the influence of SSE on condom use and sexual refusal, overal…

  • Prevalence and patterns of victimization and polyvictimization among female sex workers in Soweto, a South African township

    Open AccessJenny Coetzee, Glenda Gray et al.ARTICLEGlobal Health Action2017

    BACKGROUND: Female sex workers (FSWs) are disproportionately affected by violence from multiple partner categories. This increases their vulnerability to HIV. OBJECTIVES: To describe patterns of violence and polyvictimization among female SWs in Soweto. METHODS: test of association were used to show associations. Polyvictimization patterns are shown within a modified Venn diagram. RESULTS: The median age of FSWs in Soweto was 31 years, and most h…

  • Gender, Sexual Self-Efficacy and Consistent Condom Use Among Adolescents Living in the HIV Hyper-Endemic Setting of Soweto, South Africa

    Open AccessKalysha Closson, Janan Dietrich et al.ARTICLEAIDS and Behavior2017

  • Age-Related Differences in Socio-demographic and Behavioral Determinants of HIV Testing and Counseling in HPTN 043/Nimh Project Accept

    Open AccessThe NIMH Project Accept Study Team, Nicole Salazar‐Austin et al.ARTICLEAIDS and Behavior2017

    Youth represent a large proportion of new HIV infections worldwide, yet their utilization of HIV testing and counseling (HTC) remains low. Using the post-intervention, cross-sectional, population-based household survey done in 2011 as part of HPTN 043/NIMH Project Accept, a cluster-randomized trial of community mobilization and mobile HTC in South Africa (Soweto and KwaZulu Natal), Zimbabwe, Tanzania and Thailand, we evaluated age-related differe…