Bernhard T Baune

Biographic Data

ID4975863
NAMEBernhard T Baune
GIVEN NAMESBernhard T
FAMILY NAMEBaune
SIGNATUREBAUNE B T
AFFILIATIONSThe University of Melbourne
ORCID0000-0001-6548-426X
VERIFIEDYes
TOTAL WORKS56
TOTAL CITATIONS0
AUTHOR COUNT56
EDITOR COUNT0
FIRST PUBLICATION YEAR2005
LATEST PUBLICATION YEAR2025
H-INDEX0

  • Factors influencing patient decision-making on a multimodal precision medicine algorithm for depression

    Open AccessRosa Glaser, Johannes C S Zang et al.ARTICLEFrontiers in Psychiatry2025

    While patients are open to the use of a multimodal precision medicine algorithm for MDD, they emphasised the need for individualised, transparent communication and emotional support. The results highlight the importance of patient-centred communication strategies and guidelines for the ethical implementation of precision psychiatry

  • Attitudes towards a multimodal precision medicine algorithm for predicting treatment response in depression

    Open AccessViktor T H Wahner, Johannes C S Zang et al.ARTICLEFrontiers in Psychiatry2025

    Overall, participants indicated a large degree of acceptance towards the application of a multimodal precision medicine algorithm. Although limited by the hypothetical nature of the decision scenario, this study provides valuable perspectives from different stakeholders. Future research should move beyond attitudes and address further implementation hurdles that need to be overcome for the successful implementation of novel precision psychiatry a…

  • From cigarettes to symptoms

    Open AccessMaja P Völker, Chiara Callies et al.ARTICLEBMC Public Health2025

    Our findings support an association between smoking and depression. Robust dose-response relationships were found, with higher cigarette consumption associated with more severe depressive symptoms, and longer time since cessation linked to lower depression levels. These results highlight smoking as a meaningful and modifiable contributor to current and lifetime depression, suggesting that quitting smoking or reducing cigarette consumption may ben…

  • Burden of disease scenarios for 204 countries and territories, 2022–2050

    Open AccessStein Emil Vollset, Hazim S Ababneh et al.ARTICLEThe Lancet2024

    BACKGROUND: Future trends in disease burden and drivers of health are of great interest to policy makers and the public at large. This information can be used for policy and long-term health investment, planning, and prioritisation. We have expanded and improved upon previous forecasts produced as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) and provide a reference forecast (the most likely future), and alternativ…

  • Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021

    Open AccessMichael Brauer, Gregory A Roth et al.ARTICLEThe Lancet2024

    BACKGROUND: Understanding the health consequences associated with exposure to risk factors is necessary to inform public health policy and practice. To systematically quantify the contributions of risk factor exposures to specific health outcomes, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 aims to provide comprehensive estimates of exposure levels, relative health risks, and attributable burden of disease for 88 ri…

  • Global fertility in 204 countries and territories, 1950–2021, with forecasts to 2100

    Open AccessNatalia V Bhattacharjee, Austin E Schumacher et al.ARTICLEThe Lancet2024

    BACKGROUND: Accurate assessments of current and future fertility-including overall trends and changing population age structures across countries and regions-are essential to help plan for the profound social, economic, environmental, and geopolitical challenges that these changes will bring. Estimates and projections of fertility are necessary to inform policies involving resource and health-care needs, labour supply, education, gender equality,…

  • Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021

    Open AccessMohsen Naghavi, Kanyin Liane Ong et al.ARTICLEThe Lancet2024

    BACKGROUND: Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy worldwide are valuable metrics to gauge progress in reducing mortality rates. These estimates are particularly important following large-scale mortality spikes, such as the COVID-19 pandemic. When systematically analysed, mort…

  • Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the Covid-19 pandemic

    Open AccessAustin E Schumacher, Hmwe Hmwe Kyu et al.ARTICLEThe Lancet2024

    BACKGROUND: Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides new demographic estimates for 204 cou…

  • Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (Dalys), and healthy life expectancy (Hale) for 371 diseases and injuries in 204 countries and territor…

    Open AccessAlize J Ferrari, Damian Francesco Santomauro et al.ARTICLEThe Lancet2024

    BACKGROUND: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury burden over time and across age groups, sexes, and locations. The availability of disease burden estimates can promote evidence-based interventions that enable public health researchers, policy makers, and other professionals to im…

  • Global, regional, and national burden of disorders affecting the nervous system, 1990–2021

    Open AccessJaimie D Steinmetz, Katrin Seeher et al.ARTICLEThe Lancet Neurology2024

    BACKGROUND: Disorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Global Burden of Disease, Injuries, and Risk Factor Study estimated the burden of 15 neurological conditions in 2015 and 2016, but these analyses did not include neurodevelopmental disorders, as defined by…

  • An integrated precision medicine approach in major depressive disorder

    Open AccessBernhard T Baune, Alessandra Minelli et al.ARTICLEFrontiers in Psychiatry2024

    Major depressive disorder (MDD) is the most common psychiatric disease worldwide with a huge socio-economic impact. Pharmacotherapy represents the most common option among the first-line treatment choice; however, only about one third of patients respond to the first trial and about 30% are classified as treatment-resistant depression (TRD). TRD is associated with specific clinical features and genetic/gene expression signatures. To date, single …

  • The state of health in the European Union (EU-27) in 2019

    Open AccessJoão Vasco Santos, Alicia Padron-Monedero et al.ARTICLEBMC Public Health2024

    There was a clear trend towards improvement in the overall health status of the EU but with differences between countries. EU health policymakers need to address the burden of diseases, paying specific attention to causes such as mental disorders. There are many opportunities for mutual learning among otherwise similar countries with different patterns of disease

  • Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050

    Open AccessEmma Nichols, Jaimie D Steinmetz et al.ARTICLEThe Lancet Public Health2022

    BACKGROUND: Given the projected trends in population ageing and population growth, the number of people with dementia is expected to increase. In addition, strong evidence has emerged supporting the importance of potentially modifiable risk factors for dementia. Characterising the distribution and magnitude of anticipated growth is crucial for public health planning and resource prioritisation. This study aimed to improve on previous forecasts of…

  • Mapping genomic loci implicates genes and synaptic biology in schizophrenia

    Open AccessVassily Trubetskoy, Antonio F Pardiñas et al.ARTICLENature2022

  • Transdiagnostic Cognitive-Behavioral Therapy for Depression and Anxiety Disorders in Cardiovascular Disease Patients

    Open AccessPhillip J Tully, Deborah Turnbull et al.ARTICLEFrontiers in Psychiatry2022

    https://www.australianclinicaltrials.gov.au/anzctr/trial/ACTRN12615000555550, identifier: ACTRN12615000555550

  • Expression of CXCR4 on CD4+ T cells predicts body composition parameters in female adolescents with anorexia nervosa

    Open AccessJana Freff, Lisa Bröker et al.ARTICLEFrontiers in Psychiatry2022

    Anorexia nervosa (AN) is a severe eating disorder characterized by excessive weight loss and lack of recognition of the seriousness of the current low body weight. Individuals with AN frequently exhibit an enhanced inflammatory state and altered blood levels of cytokines and chemokines. However, the expression of chemokine receptors in AN and the association with body composition parameters and treatment effects are still unknown. In this study, …

  • Global, regional, and national progress towards Sustainable Development Goal 3.2 for neonatal and child health

    Open AccessKatherine R Paulson, Katherine Paulson et al.ARTICLEThe Lancet2021

    BACKGROUND: Sustainable Development Goal 3.2 has targeted elimination of preventable child mortality, reduction of neonatal death to less than 12 per 1000 livebirths, and reduction of death of children younger than 5 years to less than 25 per 1000 livebirths, for each country by 2030. To understand current rates, recent trends, and potential trajectories of child mortality for the next decade, we present the Global Burden of Diseases, Injuries, a…

  • Potential Genetic Overlap Between Insomnia and Sleep Symptoms in Major Depressive Disorder

    Open AccessLindsay Melhuish Beaupre, Arun K Tiwari et al.ARTICLEFrontiers in Psychiatry2021

    Background: The prevalence of insomnia and hypersomnia in depressed individuals is substantially higher than that found in the general population. Unfortunately, these concurrent sleep problems can have profound effects on the disease course. Although the full biology of sleep remains to be elucidated, a recent genome-wide association (GWAS) of insomnia, and other sleep traits in over 1 million individuals was recently published and provides many…

  • Global age-sex-specific fertility, mortality, healthy life expectancy (Hale), and population estimates in 204 countries and territories, 1950–2019

    Open AccessHaidong Wang, Kaja Abbas et al.ARTICLEThe Lancet2020

    BACKGROUND: Accurate and up-to-date assessment of demographic metrics is crucial for understanding a wide range of social, economic, and public health issues that affect populations worldwide. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 produced updated and comprehensive demographic assessments of the key indicators of fertility, mortality, migration, and population for 204 countries and territories and selected sub…

  • Five insights from the Global Burden of Disease Study 2019

    Open AccessChristopher J L Murray, Cristiana Abbafati et al.ARTICLEThe Lancet2020

  • Measuring universal health coverage based on an index of effective coverage of health services in 204 countries and territories, 1990–2019

    Open AccessR Lozano, Nancy Fullman et al.ARTICLEThe Lancet2020

    BACKGROUND: Achieving universal health coverage (UHC) involves all people receiving the health services they need, of high quality, without experiencing financial hardship. Making progress towards UHC is a policy priority for both countries and global institutions, as highlighted by the agenda of the UN Sustainable Development Goals (SDGs) and WHO's Thirteenth General Programme of Work (GPW13). Measuring effective coverage at the health-system le…

  • Global burden of 87 risk factors in 204 countries and territories, 1990–2019

    Open AccessChristopher J L Murray, Aleksandr Y Aravkin et al.ARTICLEThe Lancet2020

    BACKGROUND: Rigorous analysis of levels and trends in exposure to leading risk factors and quantification of their effect on human health are important to identify where public health is making progress and in which cases current efforts are inadequate. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a standardised and comprehensive assessment of the magnitude of risk factor exposure, relative risk, and attribu…

  • Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019

    Open AccessTheo Vos, Stephen S Lim et al.ARTICLEThe Lancet2020

    BACKGROUND: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive…

  • Symptoms of Major Depressive Disorder and Their Impact on Psychosocial Functioning in the Different Phases of the Disease

    Open AccessMichael Cronquist Christensen, Johnny Wong et al.ARTICLEFrontiers in Psychiatry2020

    This analysis was undertaken to examine the relationship between different symptoms of major depressive disorder (MDD) and psychosocial functioning from the perspectives of patients and healthcare providers (HCPs) across the different phases of the disease (acute, post-acute, and remission). Data regarding symptoms of MDD and psychosocial functioning, assessed by an adapted version of the Functioning Assessment Short Test (FAST) scale, were elici…

  • Global, regional, and national burden of neurological disorders, 1990–2016

    Open AccessValery L Feigin, Emma Nichols et al.ARTICLEThe Lancet Neurology2019

    BACKGROUND: Neurological disorders are increasingly recognised as major causes of death and disability worldwide. The aim of this analysis from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2016 is to provide the most comprehensive and up-to-date estimates of the global, regional, and national burden from neurological disorders. METHODS: We estimated prevalence, incidence, deaths, and disability-adjusted life-years (DALYs;…