Charles N Rotimi

Biographic Data

ID5207101
NAMECharles N Rotimi
GIVEN NAMESCharles N
FAMILY NAMERotimi
SIGNATUREROTIMI C N
AFFILIATIONSNational Institutes of Health
ORCID0000-0001-5759-053X
VERIFIEDYes
TOTAL WORKS11
TOTAL CITATIONS38
AUTHOR COUNT11
EDITOR COUNT0
FIRST PUBLICATION YEAR1997
LATEST PUBLICATION YEAR2019
H-INDEX2

  • The Emergence of Genomic Research in Africa and New Frameworks for Equity in Biomedical Research

    Amy R Bentley, Shawneequa Callier et al.ARTICLEEthnicity & Disease2019

    Individuals with African ancestry have the greatest genomic diversity in the world, yet they have been underrepresented in genomic research. To advance our understanding of human biology and our ability to trace human history, we must include more samples from Africans in genomic research. Additionally, inclusion of more samples from participants of recent African descent is imperative to provide equitable health care as genomics is increasingly …

  • Genetic history of Chad

    Open AccessDaniel Shriner, Charles N RotimiARTICLEAmerican Journal of Physical…2018Cited by: 2References: 35

    OBJECTIVES: The Sahel is a semi-arid zone stretching from the Atlantic Ocean in the west to the Red Sea in the east and from the Sahara in the north to the Sudanian Savanna in the south. Here, we investigated the genetic history of the spread of Northern African ancestry common among Berbers, the Y DNA haplogroup R1b-V88, and Chadic languages throughout the Sahel, with a focus on Chad. MATERIALS AND METHODS: We integrated and analyzed genotype da…

  • Diversity and inclusion in genomic research

    Open AccessAmy R Bentley, Shawneequa Callier et al.ARTICLEJournal of Community Genetics2017

    Conducting genomic research in diverse populations has led to numerous advances in our understanding of human history, biology, and health disparities, in addition to discoveries of vital clinical significance. Conducting genomic research in diverse populations is also important in ensuring that the genomic revolution does not exacerbate health disparities by facilitating discoveries that will disproportionately benefit well-represented populatio…

  • A global reference for human genetic variation

    Open AccessCorresponding authors, Adam Auton et al.ARTICLENature2015

    The 1000 Genomes Project set out to provide a comprehensive description of common human genetic variation by applying whole-genome sequencing to a diverse set of individuals from multiple populations. Here we report completion of the project, having reconstructed the genomes of 2,504 individuals from 26 populations using a combination of low-coverage whole-genome sequencing, deep exome sequencing, and dense microarray genotyping. We characterized…

  • Using a “genomics tool” to develop disease prevention strategy in a low-income setting

    Open AccessFasil Tekola-Ayele, Fasil Tekola Ayele et al.ARTICLEJournal of Community Genetics2012

  • Finding the missing heritability of complex diseases

    Open AccessTeri A Manolio, Francis S Collins et al.ARTICLENature2009

  • Voluntary Participation and Informed Consent to International Genetic Research

    Patricia A Marshall, Clement A Adebamowo et al.ARTICLEAmerican Journal of Public Health2006Cited by: 2References: 52

    Objectives. We compared voluntary participation and comprehension of informed consent among individuals of African ancestry enrolled in similarly designed genetic studies of hypertension in the United States and Nigeria. Methods. Survey questionnaires were used to evaluate factors associated with voluntariness (the number of people volunteering) and understanding of the study’s genetic purpose. A total of 655 individuals (United States: 348; Nige…

  • Ethnic and age-related fat free mass loss in older Americans

    Open AccessThomas O Obisesan, Muktar H Aliyu et al.ARTICLEBMC Public Health2005

    Age-related loss and decline in FFM and FFMI in older Americans is higher for black men and women, than for white men and women. The development of focused population-based preventive strategies is likely to improve functional independence in the aged

  • The International HapMap Project

    Open AccessRichard A Gibbs, John W Belmont et al.ARTICLENature2003

    The goal of the International HapMap Project is to determine the common patterns of DNA sequence variation in the human genome and to make this information freely available in the public domain. An international consortium is developing a map of these patterns across the genome by determining the genotypes of one million or more sequence variants, their frequencies and the degree of association between them, in DNA samples from populations with a…

  • Genetic Ancestry Tracing and the African Identity

    Open AccessCharles N RotimiARTICLEDeveloping World Bioethics2003

    As both a geneticist and a Nigerian living in the United States, the author responds to the prospect of African Americans using genetic science to trace their ancestry to the African continent. He articulates concerns about both the limitations of the science to offer satisfying, accurate, and meaningful results, and the ability of individuals to make real, life‐altering sense of these results. However, he notes that given the history and impact …

  • The prevalence of hypertension in seven populations of west African origin

    Richard Cooper, Charles N Rotimi et al.ARTICLEAmerican Journal of Public Health1997Cited by: 34References: 38

    OBJECTIVES: This study was undertaken to describe the distribution of blood pressures, hypertension prevalence, and associated risk factors among seven populations of West African origin. METHODS: The rates of hypertension in West Africa (Nigeria and Cameroon), the Caribbean (Jamaica, St. Lucia, Barbados), and the United States (metropolitan Chicago, Illinois) were compared on the basis of a highly standardized collaborative protocol. After resea…