Ian McGowan
Dados Biográficos
| ID | 5222758 |
|---|---|
| NOME | Ian McGowan |
| PRENOMES | Ian |
| SOBRENOME | McGowan |
| ASSINATURA | MCGOWAN I |
| AFILIAÇÕES | University of Pittsburgh |
| ORCID | 0000-0002-6470-8476 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 26 |
| TOTAL DE CITAÇÕES | 7 |
| TOTAL COMO AUTOR | 25 |
| TOTAL COMO EDITOR | 1 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 1989 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2024 |
| ÍNDICE H | 2 |
Affirmation, Friendship, and Volunteerism
Introduction Lesbian, gay, bisexual, trans, queer or asexual (LGBTQA+) young people are at heightened risk of suicidality and psychological distress. Interventions in various forms are required to address this issue, which should be informed by the strengths, capacity and insight of LGBTQA+ young people. Methods An online survey was promoted to LGBTQA+ young people (aged 14–21) via targeted social media advertising and community organisation diss…
The Association Between Heterosexual anal Intercourse and HIV Acquisition in Three Prospective Cohorts of Women
The extent to which receptive anal intercourse (RAI) increases the HIV acquisition risk of women compared to receptive vaginal intercourse (RVI) is poorly understood. We evaluated RAI practice over time and its association with HIV incidence during three prospective HIV cohorts of women: RV217, MTN-003 (VOICE), and HVTN 907. At baseline, 16% (RV 217), 18% (VOICE) of women reported RAI in the past 3 months and 27% (HVTN 907) in the past 6 months, …
Acceptability of a Dapivirine/Placebo Gel Administered Rectally to HIV-1 Seronegative Adults (MTN-026)
Brief Participant-Centered Convergence Interviews Integrate Self-Reports, Product Returns, and Pharmacokinetic Results to Improve Adherence Measurement in MTN-017
Factors Supporting and Hindering Adherence to Rectal Microbicide Gel Use with Receptive Anal Intercourse in a Phase 2 Trial
Patterns of a Rectal Microbicide Placebo Gel Use in a Preparatory Stage for a Phase I Trial Among Young Men Who Have Sex with Men
Preference of Oral Tenofovir Disoproxil Fumarate/Emtricitabine Versus Rectal Tenofovir Reduced-Glycerin 1% Gel Regimens for HIV Prevention Among Cisgender Men and Transgender Women Who Engage in Recep…
Lessons for Rectal Microbicide Development From an Acceptability Trial of a Placebo Gel Applied Prior to Receptive Anal Intercourse
Use of a Vaginal Ring Containing Dapivirine for HIV-1 Prevention in Women
BACKGROUND: Antiretroviral medications that are used as prophylaxis can prevent acquisition of human immunodeficiency virus type 1 (HIV-1) infection. However, in clinical trials among African women, the incidence of HIV-1 infection was not reduced, probably because of low adherence. Longer-acting methods of drug delivery, such as vaginal rings, may simplify use of antiretroviral medications and provide HIV-1 protection. METHODS: We conducted a ph…
Acceptability of Three Novel HIV Prevention Methods Among Young Male and Transgender Female Sex Workers in Puerto Rico
Tenofovir-Based Preexposure Prophylaxis for HIV Infection among African Women
BACKGROUND: Reproductive-age women need effective interventions to prevent the acquisition of human immunodeficiency virus type 1 (HIV-1) infection. METHODS: We conducted a randomized, placebo-controlled trial to assess daily treatment with oral tenofovir disoproxil fumarate (TDF), oral tenofovir-emtricitabine (TDF-FTC), or 1% tenofovir (TFV) vaginal gel as preexposure prophylaxis against HIV-1 infection in women in South Africa, Uganda, and Zimb…
Influence of Partner Type on Acceptability and Likelihood of Use of a Rectal Microbicide Among Young Men Who Have Sex With Men in the United States and Puerto Rico
This study examined how acceptability of placebo gel with receptive anal intercourse (RAI) and likelihood of future rectal microbicide use varied across partner types. Because no rectal microbicide is available yet, use of placebo permitted the study of gel use behavior in real-life circumstances. A total of 87 men who have sex with men (MSM) aged 18 to 30 years inserted placebo gel rectally before RAI during 12 weeks. Using mixed-methods design,…
Adherence to Rectal Gel Use Among Mainly Ethnic Minority Young Men Who have Sex with Men During A 3-Month Placebo Gel Trial
Rectal-Specific Microbicide Applicator
Use of a Novel Technology to Track Adherence to Product Use in a Microbicide Trial of Short Duration (MTN-007)
Successes and challenges of HIV prevention in men who have sex with men
Variations in microbicide gel acceptability among young women in the USA and Puerto Rico
In a multi-site study of vaginal microbicide acceptability conducted with sexually active young women, quantitative assessments revealed significant differences in acceptability by site. Participants in Puerto Rico rated the gel more favourably than mainland US participants in terms of liking the gel and likelihood of future use. To explain these differences, we examined responses to qualitative behavioural assessments. Young women in mainland US…
Rectal Microbicides
Tell Juliana”
Acceptability of UC781 Gel as a Rectal Microbicide Among HIV-Uninfected Women and Men
We studied the overall acceptability of UC781 gel formulation when applied rectally. Ten women and twenty-six men, all HIV-uninfected, were enrolled in a Phase 1, randomized, blinded, placebo-controlled safety and acceptability study of the vaginal microbicide gel UC781 applied rectally. Participants were randomized to three groups: 0.1% UC781 gel, 0.25% UC781 gel, or a placebo gel. Acceptability was assessed using structured questionnaires and q…
The Restoration and Eighteenth Century
William Dampier 1652–1715
Dampier wrote several accounts of his voyages as a buccaneering explorer, which took him to South America, the East Indies and Australia: New Voyage Round the World (1697); Voyage to New Holland (1703–9). He is a link between the adventurous narratives of the seventeenth century and the more scientifically documented explorations of the eighteenth. He features in the history of Alexander Selkirk, whose being marooned on Juan Fernandez gave Defoe …
James Thomson 1700–48
Brought up in the Scottish borders, Thomson came to London at 25 and eventually became acquainted with the Scriblerus wits: his poetry represents a contemporary alternative to the urban, satiric strain. His four poems on the seasons appeared 1726–30, and the complete work was repeatedly revised to 1746, having great popularity. The blank verse, latinate diction and syntax owe much to Milton. The close study of nature is set in a framework of mora…
Joseph Addison 1672–1719 Sir Richard Steele 1672–1729
Addison was educated at Charterhouse with his future colleague, Richard Steele, and at Oxford, where he became a fellow of Magdalen College. A classical scholar, he wrote Latin poetry and travelled on the Continent 1699–1703 (Dialogues upon Ancient Medals). A Whig supporter, he celebrated Marlborough's victories in verse (The Campaign, 1705), was an MP 1708–19, and held important offices (Under-Secretary of State; Chief Secretary for Ireland). Wi…
Samuel Johnson 1709–84
Johnson suffered early from defective eyesight and from scrofula, for which he was 'touched' for a cure by Queen Anne. His unusual knowledge as the son of a Lichfield bookseller took him to Pembroke College, Oxford, which poverty forced him to leave. After unsuccessful schoolteaching in the Midlands and marriage in 1734 to a much older widow, he went with his pupil David Garrick (the future actor) to London, where he contributed a wide range of w…
Affirmation, Friendship, and Volunteerism
Introduction Lesbian, gay, bisexual, trans, queer or asexual (LGBTQA+) young people are at heightened risk of suicidality and psychological distress. Interventions in various forms are required to address this issue, which should be informed by the strengths, capacity and insight of LGBTQA+ young people. Methods An online survey was promoted to LGBTQA+ young people (aged 14–21) via targeted social media advertising and community organisation diss…
Influence of Partner Type on Acceptability and Likelihood of Use of a Rectal Microbicide Among Young Men Who Have Sex With Men in the United States and Puerto Rico
This study examined how acceptability of placebo gel with receptive anal intercourse (RAI) and likelihood of future rectal microbicide use varied across partner types. Because no rectal microbicide is available yet, use of placebo permitted the study of gel use behavior in real-life circumstances. A total of 87 men who have sex with men (MSM) aged 18 to 30 years inserted placebo gel rectally before RAI during 12 weeks. Using mixed-methods design,…
Lessons for Rectal Microbicide Development From an Acceptability Trial of a Placebo Gel Applied Prior to Receptive Anal Intercourse
The Restoration and Eighteenth Century
William Dampier 1652–1715
Dampier wrote several accounts of his voyages as a buccaneering explorer, which took him to South America, the East Indies and Australia: New Voyage Round the World (1697); Voyage to New Holland (1703–9). He is a link between the adventurous narratives of the seventeenth century and the more scientifically documented explorations of the eighteenth. He features in the history of Alexander Selkirk, whose being marooned on Juan Fernandez gave Defoe …
James Thomson 1700–48
Brought up in the Scottish borders, Thomson came to London at 25 and eventually became acquainted with the Scriblerus wits: his poetry represents a contemporary alternative to the urban, satiric strain. His four poems on the seasons appeared 1726–30, and the complete work was repeatedly revised to 1746, having great popularity. The blank verse, latinate diction and syntax owe much to Milton. The close study of nature is set in a framework of mora…
Joseph Addison 1672–1719 Sir Richard Steele 1672–1729
Addison was educated at Charterhouse with his future colleague, Richard Steele, and at Oxford, where he became a fellow of Magdalen College. A classical scholar, he wrote Latin poetry and travelled on the Continent 1699–1703 (Dialogues upon Ancient Medals). A Whig supporter, he celebrated Marlborough's victories in verse (The Campaign, 1705), was an MP 1708–19, and held important offices (Under-Secretary of State; Chief Secretary for Ireland). Wi…
Samuel Johnson 1709–84
Johnson suffered early from defective eyesight and from scrofula, for which he was 'touched' for a cure by Queen Anne. His unusual knowledge as the son of a Lichfield bookseller took him to Pembroke College, Oxford, which poverty forced him to leave. After unsuccessful schoolteaching in the Midlands and marriage in 1734 to a much older widow, he went with his pupil David Garrick (the future actor) to London, where he contributed a wide range of w…
John Dryden 1631–1700
Dryden was educated at Westminster School and at Trinity College, Cambridge. He produced much of his early work in dramatic form, including (tragi-)comedy (Marriage à-la-Mode, 1672) and heroic plays in rhyme (The Conquest of Granada, 1670), later turning to blank verse (All for Love, 1678): these are now rarely performed, but his prologues reveal his practical interest in literary questions, developed in his elegant critical prose (An Essay of Dr…
Acceptability of UC781 Gel as a Rectal Microbicide Among HIV-Uninfected Women and Men
We studied the overall acceptability of UC781 gel formulation when applied rectally. Ten women and twenty-six men, all HIV-uninfected, were enrolled in a Phase 1, randomized, blinded, placebo-controlled safety and acceptability study of the vaginal microbicide gel UC781 applied rectally. Participants were randomized to three groups: 0.1% UC781 gel, 0.25% UC781 gel, or a placebo gel. Acceptability was assessed using structured questionnaires and q…
Rectal Microbicides
Tell Juliana”
Successes and challenges of HIV prevention in men who have sex with men
Variations in microbicide gel acceptability among young women in the USA and Puerto Rico
In a multi-site study of vaginal microbicide acceptability conducted with sexually active young women, quantitative assessments revealed significant differences in acceptability by site. Participants in Puerto Rico rated the gel more favourably than mainland US participants in terms of liking the gel and likelihood of future use. To explain these differences, we examined responses to qualitative behavioural assessments. Young women in mainland US…
Use of a Novel Technology to Track Adherence to Product Use in a Microbicide Trial of Short Duration (MTN-007)
Adherence to Rectal Gel Use Among Mainly Ethnic Minority Young Men Who have Sex with Men During A 3-Month Placebo Gel Trial
Rectal-Specific Microbicide Applicator
Tenofovir-Based Preexposure Prophylaxis for HIV Infection among African Women
BACKGROUND: Reproductive-age women need effective interventions to prevent the acquisition of human immunodeficiency virus type 1 (HIV-1) infection. METHODS: We conducted a randomized, placebo-controlled trial to assess daily treatment with oral tenofovir disoproxil fumarate (TDF), oral tenofovir-emtricitabine (TDF-FTC), or 1% tenofovir (TFV) vaginal gel as preexposure prophylaxis against HIV-1 infection in women in South Africa, Uganda, and Zimb…
Influence of Partner Type on Acceptability and Likelihood of Use of a Rectal Microbicide Among Young Men Who Have Sex With Men in the United States and Puerto Rico
This study examined how acceptability of placebo gel with receptive anal intercourse (RAI) and likelihood of future rectal microbicide use varied across partner types. Because no rectal microbicide is available yet, use of placebo permitted the study of gel use behavior in real-life circumstances. A total of 87 men who have sex with men (MSM) aged 18 to 30 years inserted placebo gel rectally before RAI during 12 weeks. Using mixed-methods design,…
Use of a Vaginal Ring Containing Dapivirine for HIV-1 Prevention in Women
BACKGROUND: Antiretroviral medications that are used as prophylaxis can prevent acquisition of human immunodeficiency virus type 1 (HIV-1) infection. However, in clinical trials among African women, the incidence of HIV-1 infection was not reduced, probably because of low adherence. Longer-acting methods of drug delivery, such as vaginal rings, may simplify use of antiretroviral medications and provide HIV-1 protection. METHODS: We conducted a ph…
Acceptability of Three Novel HIV Prevention Methods Among Young Male and Transgender Female Sex Workers in Puerto Rico
Brief Participant-Centered Convergence Interviews Integrate Self-Reports, Product Returns, and Pharmacokinetic Results to Improve Adherence Measurement in MTN-017
Factors Supporting and Hindering Adherence to Rectal Microbicide Gel Use with Receptive Anal Intercourse in a Phase 2 Trial
Patterns of a Rectal Microbicide Placebo Gel Use in a Preparatory Stage for a Phase I Trial Among Young Men Who Have Sex with Men
Preference of Oral Tenofovir Disoproxil Fumarate/Emtricitabine Versus Rectal Tenofovir Reduced-Glycerin 1% Gel Regimens for HIV Prevention Among Cisgender Men and Transgender Women Who Engage in Recep…
Lessons for Rectal Microbicide Development From an Acceptability Trial of a Placebo Gel Applied Prior to Receptive Anal Intercourse
Acceptability of a Dapivirine/Placebo Gel Administered Rectally to HIV-1 Seronegative Adults (MTN-026)
The Association Between Heterosexual anal Intercourse and HIV Acquisition in Three Prospective Cohorts of Women
The extent to which receptive anal intercourse (RAI) increases the HIV acquisition risk of women compared to receptive vaginal intercourse (RVI) is poorly understood. We evaluated RAI practice over time and its association with HIV incidence during three prospective HIV cohorts of women: RV217, MTN-003 (VOICE), and HVTN 907. At baseline, 16% (RV 217), 18% (VOICE) of women reported RAI in the past 3 months and 27% (HVTN 907) in the past 6 months, …
Medicine (19 obras) · HIV/AIDS Research and Interventions (17 obras) · Family medicine (14 obras) · Human immunodeficiency virus (HIV (14 obras) · Microbicide (14 obras) · Environmental health (13 obras) · Health services (13 obras) · Microbicides for sexually transmitted diseases (13 obras) · Population (12 obras) · Psychology (11 obras)