Hermann Brenner

Biographic Data

ID5458015
NAMEHermann Brenner
GIVEN NAMESHermann
FAMILY NAMEBrenner
SIGNATUREBRENNER H
AFFILIATIONSGerman Cancer Research Center
VERIFIEDNo
TOTAL WORKS49
TOTAL CITATIONS2
AUTHOR COUNT49
EDITOR COUNT0
FIRST PUBLICATION YEAR2010
LATEST PUBLICATION YEAR2025
H-INDEX1

  • Piloting a cancer awareness app across six European countries

    Open AccessFurqan Ahmed, Silvana Melissa Romero Saletti et al.ARTICLEFrontiers in Public Health2025

    Background Cancer remains a significant public health challenge in Europe, accounting for over 22% of global cancer cases. Mobile health applications may help to increase the awareness of cancer risks and preventive behaviors. However, usability barriers and disparities in digital health literacy (DHL) may limit their impact. Objective This study evaluated the usability of the EU Mobile App for Cancer Prevention and changes in cancer awareness as…

  • Burden of disease scenarios for 204 countries and territories, 2022–2050

    Open AccessStein Emil Vollset, Hazim S Ababneh et al.ARTICLEThe Lancet2024

    BACKGROUND: Future trends in disease burden and drivers of health are of great interest to policy makers and the public at large. This information can be used for policy and long-term health investment, planning, and prioritisation. We have expanded and improved upon previous forecasts produced as part of the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) and provide a reference forecast (the most likely future), and alternativ…

  • Global burden and strength of evidence for 88 risk factors in 204 countries and 811 subnational locations, 1990–2021

    Open AccessMichael Brauer, Gregory A Roth et al.ARTICLEThe Lancet2024

    BACKGROUND: Understanding the health consequences associated with exposure to risk factors is necessary to inform public health policy and practice. To systematically quantify the contributions of risk factor exposures to specific health outcomes, the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 aims to provide comprehensive estimates of exposure levels, relative health risks, and attributable burden of disease for 88 ri…

  • Global burden of 288 causes of death and life expectancy decomposition in 204 countries and territories and 811 subnational locations, 1990–2021

    Open AccessMohsen Naghavi, Kanyin Liane Ong et al.ARTICLEThe Lancet2024

    BACKGROUND: Regular, detailed reporting on population health by underlying cause of death is fundamental for public health decision making. Cause-specific estimates of mortality and the subsequent effects on life expectancy worldwide are valuable metrics to gauge progress in reducing mortality rates. These estimates are particularly important following large-scale mortality spikes, such as the COVID-19 pandemic. When systematically analysed, mort…

  • Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950–2021, and the impact of the Covid-19 pandemic

    Open AccessAustin E Schumacher, Hmwe Hmwe Kyu et al.ARTICLEThe Lancet2024

    BACKGROUND: Estimates of demographic metrics are crucial to assess levels and trends of population health outcomes. The profound impact of the COVID-19 pandemic on populations worldwide has underscored the need for timely estimates to understand this unprecedented event within the context of long-term population health trends. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2021 provides new demographic estimates for 204 cou…

  • Global incidence, prevalence, years lived with disability (YLDs), disability-adjusted life-years (Dalys), and healthy life expectancy (Hale) for 371 diseases and injuries in 204 countries and territor…

    Open AccessAlize J Ferrari, Damian Francesco Santomauro et al.ARTICLEThe Lancet2024

    BACKGROUND: Detailed, comprehensive, and timely reporting on population health by underlying causes of disability and premature death is crucial to understanding and responding to complex patterns of disease and injury burden over time and across age groups, sexes, and locations. The availability of disease burden estimates can promote evidence-based interventions that enable public health researchers, policy makers, and other professionals to im…

  • Global, regional, and national burden of disorders affecting the nervous system, 1990–2021

    Open AccessJaimie D Steinmetz, Katrin Seeher et al.ARTICLEThe Lancet Neurology2024

    BACKGROUND: Disorders affecting the nervous system are diverse and include neurodevelopmental disorders, late-life neurodegeneration, and newly emergent conditions, such as cognitive impairment following COVID-19. Previous publications from the Global Burden of Disease, Injuries, and Risk Factor Study estimated the burden of 15 neurological conditions in 2015 and 2016, but these analyses did not include neurodevelopmental disorders, as defined by…

  • Worldwide trends in underweight and obesity from 1990 to 2022

    Open AccessNowell H Phelps, Rosie Singleton et al.ARTICLEThe Lancet2024

    BACKGROUND: Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. METHODS: ). For school-aged children and adolescents, we report thinness (BMI 2 SD above the median). FINDINGS: From 1990 to 20…

  • Changes in physical activity and sedentary behavior during the first Covid-19 pandemic- restrictions in Germany

    Open AccessFlorian Herbolsheimer, Annette Peters et al.ARTICLEBMC Public Health2024

    Mobility patterns shifted towards inactivity or low-intensity activities during the nationwide restrictions in the spring of 2020, potentially leading to considerable and lasting health risks

  • The state of health in the European Union (EU-27) in 2019

    Open AccessJoão Vasco Santos, Alicia Padron-Monedero et al.ARTICLEBMC Public Health2024

    There was a clear trend towards improvement in the overall health status of the EU but with differences between countries. EU health policymakers need to address the burden of diseases, paying specific attention to causes such as mental disorders. There are many opportunities for mutual learning among otherwise similar countries with different patterns of disease

  • Global, regional, and national burden of diabetes from 1990 to 2021, with projections of prevalence to 2050

    Open AccessKanyin Liane Ong, Lauryn K Stafford et al.ARTICLEThe Lancet2023

    BACKGROUND: Diabetes is one of the leading causes of death and disability worldwide, and affects people regardless of country, age group, or sex. Using the most recent evidentiary and analytical framework from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD), we produced location-specific, age-specific, and sex-specific estimates of diabetes prevalence and burden from 1990 to 2021, the proportion of type 1 and type 2 diabetes…

  • Estimation of the global prevalence of dementia in 2019 and forecasted prevalence in 2050

    Open AccessEmma Nichols, Jaimie D Steinmetz et al.ARTICLEThe Lancet Public Health2022

    BACKGROUND: Given the projected trends in population ageing and population growth, the number of people with dementia is expected to increase. In addition, strong evidence has emerged supporting the importance of potentially modifiable risk factors for dementia. Characterising the distribution and magnitude of anticipated growth is crucial for public health planning and resource prioritisation. This study aimed to improve on previous forecasts of…

  • Population-level risks of alcohol consumption by amount, geography, age, sex, and year

    Open AccessDana Bryazka, Marissa B Reitsma et al.ARTICLEThe Lancet2022

    BACKGROUND: The health risks associated with moderate alcohol consumption continue to be debated. Small amounts of alcohol might lower the risk of some health outcomes but increase the risk of others, suggesting that the overall risk depends, in part, on background disease rates, which vary by region, age, sex, and year. METHODS: For this analysis, we constructed burden-weighted dose-response relative risk curves across 22 health outcomes to esti…

  • Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life Years for 29 Cancer Groups From 2010 to 2019

    Open AccessGlobal Burden of Disease Cancer Collaboration, Jonathan Kocarnik et al.ARTICLEJAMA Oncology2022

    IMPORTANCE: The Global Burden of Diseases, Injuries, and Risk Factors Study 2019 (GBD 2019) provided systematic estimates of incidence, morbidity, and mortality to inform local and international efforts toward reducing cancer burden. OBJECTIVE: To estimate cancer burden and trends globally for 204 countries and territories and by Sociodemographic Index (SDI) quintiles from 2010 to 2019. EVIDENCE REVIEW: The GBD 2019 estimation methods were used t…

  • Spatial, temporal, and demographic patterns in prevalence of smoking tobacco use and attributable disease burden in 204 countries and territories, 1990–2019

    Open AccessMarissa B Reitsma, Parkes J Kendrick et al.ARTICLEThe Lancet2021

    BACKGROUND: Ending the global tobacco epidemic is a defining challenge in global health. Timely and comprehensive estimates of the prevalence of smoking tobacco use and attributable disease burden are needed to guide tobacco control efforts nationally and globally. METHODS: We estimated the prevalence of smoking tobacco use and attributable disease burden for 204 countries and territories, by age and sex, from 1990 to 2019 as part of the Global B…

  • Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019

    Open AccessBin Zhou, Rodrigo M Carrillo-Larco et al.ARTICLEThe Lancet2021

    BACKGROUND: Hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories. METHODS: We used data from 1990 to 2019 on people aged 30-79 years from population-representative studies with measurement of blood pressure and data on blo…

  • Global, regional, and national burden of stroke and its risk factors, 1990–2019

    Open AccessValery L Feigin, Benjamin A Stark et al.ARTICLEThe Lancet Neurology2021

    BACKGROUND: Regularly updated data on stroke and its pathological types, including data on their incidence, prevalence, mortality, disability, risk factors, and epidemiological trends, are important for evidence-based stroke care planning and resource allocation. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) aims to provide a standardised and comprehensive measurement of these metrics at global, regional, and national leve…

  • Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories

    Open AccessAndrea Rodriguez-Martinez, Andrea Rodriguez‐Martinez et al.ARTICLEThe Lancet2020

    BACKGROUND: Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. METHODS: For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease …

  • Five insights from the Global Burden of Disease Study 2019

    Open AccessChristopher J L Murray, Cristiana Abbafati et al.ARTICLEThe Lancet2020

  • Global Burden of Cardiovascular Diseases and Risk Factors, 1990–2019

    Open AccessGregory A Roth, George A Mensah et al.ARTICLEJournal of the American College…2020

    Cardiovascular diseases (CVDs), principally ischemic heart disease (IHD) and stroke, are the leading cause of global mortality and a major contributor to disability. This paper reviews the magnitude of total CVD burden, including 13 underlying causes of cardiovascular death and 9 related risk factors, using estimates from the Global Burden of Disease (GBD) Study 2019. GBD, an ongoing multinational collaboration to provide comparable and consisten…

  • Global burden of 87 risk factors in 204 countries and territories, 1990–2019

    Open AccessChristopher J L Murray, Aleksandr Y Aravkin et al.ARTICLEThe Lancet2020

    BACKGROUND: Rigorous analysis of levels and trends in exposure to leading risk factors and quantification of their effect on human health are important to identify where public health is making progress and in which cases current efforts are inadequate. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 provides a standardised and comprehensive assessment of the magnitude of risk factor exposure, relative risk, and attribu…

  • Global burden of 369 diseases and injuries in 204 countries and territories, 1990–2019

    Open AccessTheo Vos, Stephen S Lim et al.ARTICLEThe Lancet2020

    BACKGROUND: In an era of shifting global agendas and expanded emphasis on non-communicable diseases and injuries along with communicable diseases, sound evidence on trends by cause at the national level is essential. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic scientific assessment of published, publicly available, and contributed data on incidence, prevalence, and mortality for a mutually exclusive…

  • World Health Organization cardiovascular disease risk charts

    Open AccessStephen Kaptoge, Lisa Pennells et al.ARTICLEThe Lancet Global Health2019

    BACKGROUND: To help adapt cardiovascular disease risk prediction approaches to low-income and middle-income countries, WHO has convened an effort to develop, evaluate, and illustrate revised risk models. Here, we report the derivation, validation, and illustration of the revised WHO cardiovascular disease risk prediction charts that have been adapted to the circumstances of 21 global regions. METHODS: In this model revision initiative, we derived…

  • Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2017

    Open AccessChristina Fitzmaurice, Global Burden of Disease Cancer Collaboration et al.ARTICLEJAMA Oncology2019

    Importance Cancer and other noncommunicable diseases (NCDs) are now widely recognized as a threat to global development. The latest United Nations high-level meeting on NCDs reaffirmed this observation and also highlighted the slow progress in meeting the 2011 Political Declaration on the Prevention and Control of Noncommunicable Diseases and the third Sustainable Development Goal. Lack of situational analyses, priority setting, and budgeting hav…

  • Rising rural body-mass index is the main driver of the global obesity epidemic in adults

    Open AccessNCD Risk Factor Collaboration, Honor Bixby et al.ARTICLENature2019

    Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities 1,2 . This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity 3–6 . Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean B…