Christos Pantelis
Biographic Data
| ID | 5552407 |
|---|---|
| NAME | Christos Pantelis |
| GIVEN NAMES | Christos |
| FAMILY NAME | Pantelis |
| SIGNATURE | PANTELIS C |
| AFFILIATIONS | The University of Melbourne |
| ORCID | 0000-0002-9565-0238 |
| VERIFIED | Yes |
| TOTAL WORKS | 12 |
| TOTAL CITATIONS | 0 |
| AUTHOR COUNT | 12 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2014 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 0 |
Foundations of the Alive National Centre for Mental Health Research Translation
The ALIVE National Centre for Mental Health Research Translation was established in 2021. Funded by the Australian National Health and Medical Research Council's Special Initiative in Mental Health, the Centre aims to foster innovation in mental health care. Central to this aim is embedding the voices of those with lived experience into all Centre structures and activities including leadership and co-design of research priorities for mental healt…
Exploring the predictive value of structural covariance networks for the diagnosis of schizophrenia
These patterns of results show that different SCN computation approaches capture different aspects of the disease. While REF-SCNs contain valuable information for discriminating schizophrenia from healthy control individuals, KLS-SCNs may capture more nuanced symptom-level characteristics similar to those captured by PCA of regional GMV
Gross anatomical features of the insular cortex in affective disorders
The present results indicate that changes in the gross morphology of the insular cortex in BD and MDD is a potential vulnerability factor associated with their neurodevelopmental pathologies, and may also contribute to the severity of symptoms in MDD
The heterogeneity of attenuated and brief limited psychotic symptoms
Psychosis-risk patients report a wide range of different contents of APS/BIPS, underlining the psychopathological heterogeneity of this group but also revealing a potential core set of contents. Compared to earlier reports on North-American samples, our maximum prevalence rates of contents were considerably lower; this likely being related to a stricter rating of APS/BIPS and cultural influences, in particular, higher schizotypy reported in North…
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Add-On MEmaNtine to Dopamine Antagonism to Improve Negative Symptoms at First Psychosis- the Amend Trial Protocol
[ClinicalTrials.gov], identifier [NCT04789915]
Heschl’s gyrus duplication pattern and clinical characteristics in borderline personality disorder
Inter-individual variations in the sulco-gyral pattern of Heschl's gyrus (HG) might contribute to emotional processing. However, it remains largely unknown whether borderline personality disorder (BPD) patients exhibit an altered HG gyrification pattern, compared with healthy individuals, and whether such a brain morphological feature, if present, might contribute to their clinical characteristics. The present study used magnetic resonance imagin…
No Effects of Cognitive Remediation on Cerebral White Matter in Individuals at Ultra-High Risk for Psychosis—A Randomized Clinical Trial
ClinicalTrials.gov, identifier NCT02098408
Basic Symptoms Are Associated With Age in Patients With a Clinical High-Risk State for Psychosis
In community studies, both attenuated psychotic symptoms (APS) and basic symptoms (BS) were more frequent but less clinically relevant in children and adolescents compared to adults. In doing so, they displayed differential age thresholds that were around age 16 for APS, around age 18 for perceptive BS, and within the early twenties for cognitive BS. Only the age effect has previously been studied and replicated in clinical samples for APS. Thus,…
Pineal Gland Volume in Major Depressive and Bipolar Disorders
Abnormal melatonin secretion has been demonstrated in patients with affective disorders such as major depressive disorder (MDD) and bipolar disorder (BD). However, magnetic resonance imaging (MRI) studies that previously investigated the volume of the pineal gland, which regulates circadian rhythms by secreting melatonin, in these patients reported inconsistent findings. The present study employed MRI to examine pineal gland volumes and pineal cy…
Peripheral Transcription of NRG-ErbB Pathway Genes Are Upregulated in Treatment-Resistant Schizophrenia
Investigation of peripheral gene expression patterns of transcripts within the NRG-ErbB signaling pathway, other than neuregulin-1 ( NRG1 ), among patients with schizophrenia and more specifically treatment-resistant schizophrenia (TRS) is limited. The present study built on our previous work demonstrating elevated levels of NRG1 EGFα, EGFβ, and type I (Ig2) containing transcripts in TRS by investigating 11 NRG-ErbB signaling pathway mRNA transcr…
Functional and Structural Alterations in the Cingulate Motor Area Relate to Decreased Fronto-Striatal Coupling in Major Depressive Disorder with Psychomotor Disturbances
Psychomotor disturbances are a classic feature of major depressive disorders. These can manifest as lack of facial expressions and decreased speech production, reduced body posture and mobility, and slowed voluntary movement. The neural correlates of psychomotor disturbances in depression are poorly understood but it has been suggested that outputs from the cingulate motor area (CMA) to striatal motor regions, including the putamen, could be invo…
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Functional and Structural Alterations in the Cingulate Motor Area Relate to Decreased Fronto-Striatal Coupling in Major Depressive Disorder with Psychomotor Disturbances
Psychomotor disturbances are a classic feature of major depressive disorders. These can manifest as lack of facial expressions and decreased speech production, reduced body posture and mobility, and slowed voluntary movement. The neural correlates of psychomotor disturbances in depression are poorly understood but it has been suggested that outputs from the cingulate motor area (CMA) to striatal motor regions, including the putamen, could be invo…
Peripheral Transcription of NRG-ErbB Pathway Genes Are Upregulated in Treatment-Resistant Schizophrenia
Investigation of peripheral gene expression patterns of transcripts within the NRG-ErbB signaling pathway, other than neuregulin-1 ( NRG1 ), among patients with schizophrenia and more specifically treatment-resistant schizophrenia (TRS) is limited. The present study built on our previous work demonstrating elevated levels of NRG1 EGFα, EGFβ, and type I (Ig2) containing transcripts in TRS by investigating 11 NRG-ErbB signaling pathway mRNA transcr…
No Effects of Cognitive Remediation on Cerebral White Matter in Individuals at Ultra-High Risk for Psychosis—A Randomized Clinical Trial
ClinicalTrials.gov, identifier NCT02098408
Basic Symptoms Are Associated With Age in Patients With a Clinical High-Risk State for Psychosis
In community studies, both attenuated psychotic symptoms (APS) and basic symptoms (BS) were more frequent but less clinically relevant in children and adolescents compared to adults. In doing so, they displayed differential age thresholds that were around age 16 for APS, around age 18 for perceptive BS, and within the early twenties for cognitive BS. Only the age effect has previously been studied and replicated in clinical samples for APS. Thus,…
Pineal Gland Volume in Major Depressive and Bipolar Disorders
Abnormal melatonin secretion has been demonstrated in patients with affective disorders such as major depressive disorder (MDD) and bipolar disorder (BD). However, magnetic resonance imaging (MRI) studies that previously investigated the volume of the pineal gland, which regulates circadian rhythms by secreting melatonin, in these patients reported inconsistent findings. The present study employed MRI to examine pineal gland volumes and pineal cy…
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Add-On MEmaNtine to Dopamine Antagonism to Improve Negative Symptoms at First Psychosis- the Amend Trial Protocol
[ClinicalTrials.gov], identifier [NCT04789915]
Heschl’s gyrus duplication pattern and clinical characteristics in borderline personality disorder
Inter-individual variations in the sulco-gyral pattern of Heschl's gyrus (HG) might contribute to emotional processing. However, it remains largely unknown whether borderline personality disorder (BPD) patients exhibit an altered HG gyrification pattern, compared with healthy individuals, and whether such a brain morphological feature, if present, might contribute to their clinical characteristics. The present study used magnetic resonance imagin…
The heterogeneity of attenuated and brief limited psychotic symptoms
Psychosis-risk patients report a wide range of different contents of APS/BIPS, underlining the psychopathological heterogeneity of this group but also revealing a potential core set of contents. Compared to earlier reports on North-American samples, our maximum prevalence rates of contents were considerably lower; this likely being related to a stricter rating of APS/BIPS and cultural influences, in particular, higher schizotypy reported in North…
Gross anatomical features of the insular cortex in affective disorders
The present results indicate that changes in the gross morphology of the insular cortex in BD and MDD is a potential vulnerability factor associated with their neurodevelopmental pathologies, and may also contribute to the severity of symptoms in MDD
Foundations of the Alive National Centre for Mental Health Research Translation
The ALIVE National Centre for Mental Health Research Translation was established in 2021. Funded by the Australian National Health and Medical Research Council's Special Initiative in Mental Health, the Centre aims to foster innovation in mental health care. Central to this aim is embedding the voices of those with lived experience into all Centre structures and activities including leadership and co-design of research priorities for mental healt…
Exploring the predictive value of structural covariance networks for the diagnosis of schizophrenia
These patterns of results show that different SCN computation approaches capture different aspects of the disease. While REF-SCNs contain valuable information for discriminating schizophrenia from healthy control individuals, KLS-SCNs may capture more nuanced symptom-level characteristics similar to those captured by PCA of regional GMV
Medicine (9 works) · Psychology (9 works) · Psychiatry (8 works) · Functional Brain Connectivity Studies (6 works) · Internal Medicine (6 works) · Clinical Psychology (5 works) · Clinical Psychology (5 works) · Neuroscience (5 works) · Psychosis (4 works) · Schizophrenia (object-oriented programming (4 works)