Mhairi Maskew
Biographic Data
| ID | 6806696 |
|---|---|
| NAME | Mhairi Maskew |
| GIVEN NAMES | Mhairi |
| FAMILY NAME | Maskew |
| SIGNATURE | MASKEW M |
| AFFILIATIONS | University of the Witwatersrand |
| ORCID | 0000-0003-4238-0200 |
| VERIFIED | Yes |
| TOTAL WORKS | 15 |
| TOTAL CITATIONS | 1 |
| AUTHOR COUNT | 15 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2011 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 1 |
Postpartum continuity of care for women with HIV
Introduction Postpartum disengagement from HIV care increases risks for adverse maternal health outcomes and transmission of HIV through breastfeeding. In January 2015, South Africa implemented Option B+, a policy extending lifelong antiretroviral therapy (ART) eligibility to all pregnant women living with HIV (PWLWH) regardless of CD4 count. We assessed the impact of Option B+ on postpartum retention in HIV care for PWLWH and identified predicto…
Who does tracing work for? Characteristics of clients successfully re-engaged in ART care in sub-Saharan Africa after a tracing intervention
Tracing HIV treatment clients who have interrupted or disengaged from care is a common, guideline-recommended practice globally. Most guidelines prioritize tracing based on clinical condition or HIV transmission risk, not likelihood of client traits that may affect return to care after tracing. Targeting tracing to those most likely to return could increase efficiency substantially. We conducted a systematic review to identify characteristics of …
Patterns of engagement in care during clients’ first 12 months after HIV treatment initiation in Zambia
BACKGROUND: The first year after HIV treatment initiation or re-initiation is the period of highest risk of a treatment interruption or disengagement, yet little is known about the timing, patterns and effects of interruptions in the early treatment period. METHODS: Using routinely collected electronic medical record data from 543 Zambian facilities from 2018 to 2023, we described patterns of engagement during the first year of HIV treatment. We …
Effect of same-day HIV treatment initiation (SDI) on 1-year outcomes in low- and middle-income countries
Characteristics and six-month viral load suppression of clients presenting with advanced HIV disease in South Africa
Despite advances in antiretroviral therapy (ART), a notable proportion of individuals still present with advanced HIV disease (AHD) at treatment initiation, defined by CD4
Drivers of disengagement from care during the first six months on antiretroviral therapy for HIV in South Africa
For clients on HIV treatment in sub-Saharan Africa, early disengagement from care is a critical obstacle to achieving UNAIDS’s second 95 target. While South Africa’s Differentiated Service Delivery Guideline on Fast Track Initiation and Counseling (FTIC) defines normative procedures, the impact of implementation and drivers of disengagement remain unclear. The PREFER mixed-methods study enrolled a prospective cohort of adult clients initiating AR…
Experiences and Preferences in Zambia and South Africa for Delivery of HIV Treatment During a Client’s First Six Months
Disengagement from antiretroviral therapy (ART) is highest in the early treatment period (≤ 6 months after initiation/re-initiation), but low intensity models designed to increase retention generally exclude these clients. We describe client preferences for HIV service delivery in the early treatment period. From 9/2022 to 6/2023, we surveyed adult clients who were initiating or on ART for ≤ 6 months at primary health facilities in South Africa a…
Patterns of engagement in care during clients’ first 12 months after HIV treatment initiation in South Africa
Retention on antiretroviral therapy (ART) during the early treatment period is one of the most serious challenges facing HIV programs, but the timing and patterns of early disengagement from care remain poorly understood. We describe patterns of engagement in HIV care during the first year after treatment initiation. We analysed retrospective datasets of routinely collected electronic medical register (EMR) data for ≥18-year-old clients who initi…
Historical visit attendance as predictor of treatment interruption in South African HIV patients
Retention of antiretroviral (ART) patients is a priority for achieving HIV epidemic control in South Africa. While machine-learning methods are being increasingly utilised to identify high risk populations for suboptimal HIV service utilisation, they are limited in terms of explaining relationships between predictors. To further understand these relationships, we implemented machine learning methods optimised for predictive power and traditional …
Assessment of facility-level antiretroviral treatment patient status utilizing a national-level laboratory cohort
Background: Most estimates of HIV retention are derived at the clinic level through antiretroviral (ART) patient management systems, which capture ART clinic visit data, yet these cannot account for silent transfers across HIV treatment sites. Patient laboratory monitoring visits may also be observed in routinely collected laboratory data, which include ART monitoring tests such as CD4 count and HIV viral load, key to our work here. Methods: In t…
The South African National HIV Pregnancy Cohort
N/A (not a clinical trial)
“Even if you’re HIV-positive there’s life after if you take your medication”
South Africa's national antiretroviral treatment (ART) programme, initiated in 2004, is the largest HIV treatment programme in the world with an estimated 4.2 million people on ART. Today, an HIV diagnosis is no longer associated with certain death, but is rather a manageable chronic disease, with all HIV-positive patients now eligible to receive treatment. In this study, we explore patient experiences at the onset of the ART programme, including…
Acceptability and feasibility of a financial incentive intervention to improve retention in HIV care among pregnant women in Johannesburg, South Africa
Women initiating antiretroviral therapy during pregnancy are at high risk of dropping out of HIV care after delivery. We assessed the acceptability and feasibility of a financial incentive - a one-time R50 (∼USD4) supermarket voucher for completing one postpartum visit ≤10 weeks of delivery - to improve postpartum retention. We enrolled 100 pregnant, HIV-positive women at a primary health clinic in Johannesburg, South Africa. Participants were in…
Comparison of Pharmacy-Based Measures of Adherence to Antiretroviral Therapy as Predictors of Virological Failure
Paediatric human immunodeficiency virus treatment outcomes from a resource-limited setting in South Africa
Comprehensive care of human immunodeficiency virus (HIV)-infected children in the resource-poor setting is challenging, and published reports on treatment outcomes in this setting are limited. The aim of this study was to evaluate outcomes of HIV-infected children initiated on highly active antiretroviral therapy (HAART) between April 2005 and April 2009 at a primary health-care centre in Alexandra Township, South Africa. Of the 337 patients init…
Paediatric human immunodeficiency virus treatment outcomes from a resource-limited setting in South Africa
Comprehensive care of human immunodeficiency virus (HIV)-infected children in the resource-poor setting is challenging, and published reports on treatment outcomes in this setting are limited. The aim of this study was to evaluate outcomes of HIV-infected children initiated on highly active antiretroviral therapy (HAART) between April 2005 and April 2009 at a primary health-care centre in Alexandra Township, South Africa. Of the 337 patients init…
Paediatric human immunodeficiency virus treatment outcomes from a resource-limited setting in South Africa
Comprehensive care of human immunodeficiency virus (HIV)-infected children in the resource-poor setting is challenging, and published reports on treatment outcomes in this setting are limited. The aim of this study was to evaluate outcomes of HIV-infected children initiated on highly active antiretroviral therapy (HAART) between April 2005 and April 2009 at a primary health-care centre in Alexandra Township, South Africa. Of the 337 patients init…
Comparison of Pharmacy-Based Measures of Adherence to Antiretroviral Therapy as Predictors of Virological Failure
Acceptability and feasibility of a financial incentive intervention to improve retention in HIV care among pregnant women in Johannesburg, South Africa
Women initiating antiretroviral therapy during pregnancy are at high risk of dropping out of HIV care after delivery. We assessed the acceptability and feasibility of a financial incentive - a one-time R50 (∼USD4) supermarket voucher for completing one postpartum visit ≤10 weeks of delivery - to improve postpartum retention. We enrolled 100 pregnant, HIV-positive women at a primary health clinic in Johannesburg, South Africa. Participants were in…
“Even if you’re HIV-positive there’s life after if you take your medication”
South Africa's national antiretroviral treatment (ART) programme, initiated in 2004, is the largest HIV treatment programme in the world with an estimated 4.2 million people on ART. Today, an HIV diagnosis is no longer associated with certain death, but is rather a manageable chronic disease, with all HIV-positive patients now eligible to receive treatment. In this study, we explore patient experiences at the onset of the ART programme, including…
The South African National HIV Pregnancy Cohort
N/A (not a clinical trial)
Assessment of facility-level antiretroviral treatment patient status utilizing a national-level laboratory cohort
Background: Most estimates of HIV retention are derived at the clinic level through antiretroviral (ART) patient management systems, which capture ART clinic visit data, yet these cannot account for silent transfers across HIV treatment sites. Patient laboratory monitoring visits may also be observed in routinely collected laboratory data, which include ART monitoring tests such as CD4 count and HIV viral load, key to our work here. Methods: In t…
Historical visit attendance as predictor of treatment interruption in South African HIV patients
Retention of antiretroviral (ART) patients is a priority for achieving HIV epidemic control in South Africa. While machine-learning methods are being increasingly utilised to identify high risk populations for suboptimal HIV service utilisation, they are limited in terms of explaining relationships between predictors. To further understand these relationships, we implemented machine learning methods optimised for predictive power and traditional …
Patterns of engagement in care during clients’ first 12 months after HIV treatment initiation in South Africa
Retention on antiretroviral therapy (ART) during the early treatment period is one of the most serious challenges facing HIV programs, but the timing and patterns of early disengagement from care remain poorly understood. We describe patterns of engagement in HIV care during the first year after treatment initiation. We analysed retrospective datasets of routinely collected electronic medical register (EMR) data for ≥18-year-old clients who initi…
Patterns of engagement in care during clients’ first 12 months after HIV treatment initiation in Zambia
BACKGROUND: The first year after HIV treatment initiation or re-initiation is the period of highest risk of a treatment interruption or disengagement, yet little is known about the timing, patterns and effects of interruptions in the early treatment period. METHODS: Using routinely collected electronic medical record data from 543 Zambian facilities from 2018 to 2023, we described patterns of engagement during the first year of HIV treatment. We …
Effect of same-day HIV treatment initiation (SDI) on 1-year outcomes in low- and middle-income countries
Characteristics and six-month viral load suppression of clients presenting with advanced HIV disease in South Africa
Despite advances in antiretroviral therapy (ART), a notable proportion of individuals still present with advanced HIV disease (AHD) at treatment initiation, defined by CD4
Drivers of disengagement from care during the first six months on antiretroviral therapy for HIV in South Africa
For clients on HIV treatment in sub-Saharan Africa, early disengagement from care is a critical obstacle to achieving UNAIDS’s second 95 target. While South Africa’s Differentiated Service Delivery Guideline on Fast Track Initiation and Counseling (FTIC) defines normative procedures, the impact of implementation and drivers of disengagement remain unclear. The PREFER mixed-methods study enrolled a prospective cohort of adult clients initiating AR…
Experiences and Preferences in Zambia and South Africa for Delivery of HIV Treatment During a Client’s First Six Months
Disengagement from antiretroviral therapy (ART) is highest in the early treatment period (≤ 6 months after initiation/re-initiation), but low intensity models designed to increase retention generally exclude these clients. We describe client preferences for HIV service delivery in the early treatment period. From 9/2022 to 6/2023, we surveyed adult clients who were initiating or on ART for ≤ 6 months at primary health facilities in South Africa a…
Postpartum continuity of care for women with HIV
Introduction Postpartum disengagement from HIV care increases risks for adverse maternal health outcomes and transmission of HIV through breastfeeding. In January 2015, South Africa implemented Option B+, a policy extending lifelong antiretroviral therapy (ART) eligibility to all pregnant women living with HIV (PWLWH) regardless of CD4 count. We assessed the impact of Option B+ on postpartum retention in HIV care for PWLWH and identified predicto…
Who does tracing work for? Characteristics of clients successfully re-engaged in ART care in sub-Saharan Africa after a tracing intervention
Tracing HIV treatment clients who have interrupted or disengaged from care is a common, guideline-recommended practice globally. Most guidelines prioritize tracing based on clinical condition or HIV transmission risk, not likelihood of client traits that may affect return to care after tracing. Targeting tracing to those most likely to return could increase efficiency substantially. We conducted a systematic review to identify characteristics of …
HIV/AIDS Research and Interventions (14 works) · Medicine (10 works) · Family medicine (8 works) · Adolescent Sexual and Reproductive Health (6 works) · Cohort (6 works) · Cohort study (5 works) · Disengagement theory (5 works) · HIV Research and Treatment (5 works) · Internal Medicine (5 works) · Public health (5 works)