Danielle Posthuma
Dados Biográficos
| ID | 7522836 |
|---|---|
| NOME | Danielle Posthuma |
| PRENOMES | Danielle |
| SOBRENOME | Posthuma |
| ASSINATURA | POSTHUMA D |
| AFILIAÇÕES | Center for Neurogenomics and Cognitive Research Neuroscience Campus Amsterdam, VU University Amsterdam |
| ORCID | 0000-0001-7582-2365 |
| VERIFICADO | Sim |
| TOTAL DE OBRAS | 8 |
| TOTAL DE CITAÇÕES | 0 |
| TOTAL COMO AUTOR | 8 |
| TOTAL COMO EDITOR | 0 |
| PRIMEIRO ANO DE PUBLICAÇÃO | 2013 |
| ANO MAIS RECENTE DE PUBLICAÇÃO | 2025 |
| ÍNDICE H | 0 |
Socio-medical factors associated with neurodevelopmental disorders on the Kenyan coast
Neurodevelopmental disorders (NDDs) are a group of conditions with their onset during the early developmental period and include conditions such as autism and intellectual disability. Occurrence of NDDs is thought to be determined by both genetic and environmental factors, but data on the role of environmental factors for NDD in Africa is limited. This study investigates environmental influences on NDDs in children from Kenya. This case-control s…
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wide polygenic predictor, or polygenic index (PGI), explains 12–16% of EA variance and contributes to risk prediction for ten diseases. Direct effects (i.e., controlling for parental PGIs) explain roughly half th…
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Genome-wide association study identifies 74 loci associated with educational attainment
Meta-analysis of the heritability of human traits based on fifty years of twin studies
Core Dimensions of Personality Broadly Account for the Link from Perceived Social Support to Symptoms of Depression and Anxiety
Specific personality traits and poor social support are risk factors for anxiety and depression. Little work, however, has considered the effects of social support and personality on these aspects of psychopathology simultaneously. We examined whether perceived social support mediates the effects of core personality domains on symptoms of anxiety and depression. Measures of personality (based on the Five‐Factor Model [ FFM ]), perceived social su…
GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment
Genetic College Many genomic elements in humans are associated with behavior, including educational attainment. In a genome-wide association study including more than 100,000 samples, Rietveld et al. (p. 1467 , published online 30 May; see the Perspective by Flint and Munafò ) looked for genes related to educational attainment in Caucasians. Small genetic effects at three loci appeared to impact educational attainment.
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GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment
Genetic College Many genomic elements in humans are associated with behavior, including educational attainment. In a genome-wide association study including more than 100,000 samples, Rietveld et al. (p. 1467 , published online 30 May; see the Perspective by Flint and Munafò ) looked for genes related to educational attainment in Caucasians. Small genetic effects at three loci appeared to impact educational attainment.
Core Dimensions of Personality Broadly Account for the Link from Perceived Social Support to Symptoms of Depression and Anxiety
Specific personality traits and poor social support are risk factors for anxiety and depression. Little work, however, has considered the effects of social support and personality on these aspects of psychopathology simultaneously. We examined whether perceived social support mediates the effects of core personality domains on symptoms of anxiety and depression. Measures of personality (based on the Five‐Factor Model [ FFM ]), perceived social su…
Meta-analysis of the heritability of human traits based on fifty years of twin studies
Genome-wide association study identifies 74 loci associated with educational attainment
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Mapping genomic loci implicates genes and synaptic biology in schizophrenia
Polygenic prediction of educational attainment within and between families from genome-wide association analyses in 3 million individuals
We conduct a genome-wide association study (GWAS) of educational attainment (EA) in a sample of ~3 million individuals and identify 3,952 approximately uncorrelated genome-wide-significant single-nucleotide polymorphisms (SNPs). A genome-wide polygenic predictor, or polygenic index (PGI), explains 12–16% of EA variance and contributes to risk prediction for ten diseases. Direct effects (i.e., controlling for parental PGIs) explain roughly half th…
Socio-medical factors associated with neurodevelopmental disorders on the Kenyan coast
Neurodevelopmental disorders (NDDs) are a group of conditions with their onset during the early developmental period and include conditions such as autism and intellectual disability. Occurrence of NDDs is thought to be determined by both genetic and environmental factors, but data on the role of environmental factors for NDD in Africa is limited. This study investigates environmental influences on NDDs in children from Kenya. This case-control s…
Biology (6 obras) · Gene (5 obras) · Genetic Associations and Epidemiology (5 obras) · Genetics (5 obras) · Genetic association (4 obras) · Genome-wide association study (4 obras) · Genotype (4 obras) · Single-nucleotide polymorphism (4 obras) · Genome (3 obras) · Birth, Development, and Health (2 obras)