Salim S Abdool Karim

Biographic Data

ID	7728640
NAME	Salim S Abdool Karim
GIVEN NAMES	Salim S Abdool
FAMILY NAME	Karim
SIGNATURE	KARIM S S A
AFFILIATIONS	Centre for the AIDS Programme of Research in South Africa
ORCID	0000-0002-4986-2133
VERIFIED	Yes
TOTAL WORKS	38
TOTAL CITATIONS	51
AUTHOR COUNT	38
EDITOR COUNT	0
FIRST PUBLICATION YEAR	1989
LATEST PUBLICATION YEAR	2026
H-INDEX	4

Written on the Skin
Open AccessEmma Durden, Eliza Govender et al.ARTICLEAIDS and Behavior2026
To address challenges associated with the uptake of daily oral pre-exposure prophylaxis (PrEP) by young women at high risk of acquiring HIV, a range of novel, long-acting, slow-release products are being developed and clinically evaluated. One such technology is an annual implant of tenofovir alafenamide (TAF). This study explores the perspectives of participants from a first-in-human trial of an annual TAF implant to inform considerations for fu…
“There is nobody who wouldn’t like to”
Open AccessEmma Durden, Eliza Govender et al.ARTICLEAIDS Care2026
A novel long-acting HIV oral pre-exposure prophylaxis (PrEP) implant was first tested in a Phase I clinical trial in South Africa, and this study sought to understand motivations behind trial participants enrolment, highlighting considerations for recruitment in future studies. Qualitative research was conducted using in-depth interviews (IDIs) with 29 study participants, 18 of whom also participated in focus group discussions (FGDs). Participant…
Vaccine access, equity and justice
Open AccessLois Privor-Dumm, Jean-Louis Excler et al.ARTICLEBMJ Global Health2023
Although significant progress has been made in achieving goals for COVID-19 vaccine access, the quest for equity and justice remains an unfinished agenda. Vaccine nationalism has prompted calls for new approaches to achieve equitable access and justice not only for vaccines but also for vaccination. This includes ensuring country and community participation in global discussions and that local needs to strengthen health systems, address issues re…
Covid-19 vaccines and the pandemic
Open AccessPeter J Hotez, Sarah Gilbert et al.ARTICLEBMJ Global Health2023
Through the experiences gained by accelerating new vaccines for both Ebola virus infection and COVID-19 in a public health emergency, vaccine development has benefited from a ‘multiple shots on goal’ approach to new vaccine targets. This approach embraces simultaneous development of candidates with differing technologies, including, when feasible, vesicular stomatitis virus or adenovirus vectors, messenger RNA (mRNA), whole inactivated virus, nan…
Factors, enablers and challenges for Covid-19 vaccine development
Open AccessJean-Louis Excler, Melanie Saville et al.ARTICLEBMJ Global Health2023
The COVID-19 pandemic triggered a sense of vulnerability and urgency that led to concerted actions by governments, funders, regulators and industry to overcome traditional challenges for the development of vaccine candidates and to reach authorisation. Unprecedented financial investments, massive demand, accelerated clinical development and regulatory reviews were among the key factors that contributed to accelerating the development and approval…
Covid-19
Safura Abdool Karim, Quarraisha Abdool Karim et al.ARTICLESocial research2023
Several safe and effective COVID-19 vaccines were developed, evaluated, and made available in record time during the pandemic. But hopes of equitable access to COVID-19 vaccines were dashed by corporate greed, political expediency, global trade agreements, and intellectual property ownership, delaying or denying access for poor countries. Once vaccines became widely available, their benefits were curtailed by anti-science sentiment and anti-vacci…
The Lancet Commission on lessons for the future from the Covid-19 pandemic
Open AccessJeff Sachs, Jeffrey D Sachs et al.ARTICLEThe Lancet2022
Covid-19 vaccine wastage in the midst of vaccine inequity
Open AccessJeffrey V Lazarus, Salim S Abdool Karim et al.ARTICLEBMJ Global Health2022
Public understanding of science
Open AccessSalim S Abdool KarimARTICLEPublic Understanding of Science2022
While Covid-19 created unprecedented transparency with real-time reporting across the globe, the pandemic’s politically charged environment made public communication of scientific information particularly challenging. Scientists, as authoritative voices, were thrust into the public eye to explain the evidence amid uncertainty, a changing virus, distrust in government and concerns about their self-interest and hidden agendas. Honest communication …
Omicron Sars-CoV-2 variant
Open AccessSalim S Abdool Karim, Quarraisha Abdool KarimARTICLEThe Lancet2021
Acceptability of Early Antiretroviral Therapy Among South African Women
Open AccessNigel Garrett, Emily Norman et al.ARTICLEAIDS and Behavior2017
Social Context of Adherence in an Open-Label 1 % Tenofovir Gel Trial
Open AccessKathleen M Macqueen, Sarah Dlamini et al.ARTICLEAIDS and Behavior2016
CAPRISA 008, an open-label extension study of tenofovir gel with coitally-related dosing, provided an opportunity to explore the relationship between product adherence and gender dynamics in a context where women knew they were receiving an active product with evidence of HIV prevention effectiveness. Interviews with 63 CAPRISA 008 participants and 13 male partners in KwaZulu-Natal, South Africa, highlighted that the process of negotiating gel us…
Risk Factors for HIV Acquisition in High Risk Women in a Generalised Epidemic Setting
Open AccessNivashnee Naicker, Ayesha B M Kharsany et al.ARTICLEAIDS and Behavior2015
HIV-Positive Status Disclosure in Patients in Care in Rural South Africa
Open AccessQuarraisha Abdool Karim, Rachael Dellar et al.ARTICLEAIDS and Behavior2015
Trial participation disclosure and gel use behavior in the Caprisa 004 tenofovir gel trial
Stacey Succop, Stacey M Succop et al.ARTICLEAIDS Care2014
Disclosure, or open communication, by female microbicide trial participants of their trial participation and use of an investigational HIV prevention drug to a sexual partner may affect participants' trial product usage behavior and contribute to poor adherence. With mixed results from recent microbicide clinical trials being linked to differing participant adherence, insights into the communication dynamics between trial participants and their s…
Impact of Antiretroviral Therapy on Health-Related Quality of Life among South African Women in the Caprisa 002 Acute Infection Study
Open AccessAndrew Tomita, Nigel Garrett et al.ARTICLEAIDS and Behavior2014
Disclosure of Microbicide Gel Use to Sexual Partners
Open AccessKathryn Mngadi, Kathryn Therese Mngadi et al.ARTICLEAIDS and Behavior2014
Assessing Adherence in the Caprisa 004 Tenofovir Gel HIV Prevention Trial
Open AccessKathleen M Macqueen, Mark A Weaver et al.ARTICLEAIDS and Behavior2014
Adherence undeniably impacts product effectiveness in microbicide trials, but the connection has proven challenging to quantify using routinely collected behavioral data. We explored this relationship using a nested case-control study in the CAPRISA 004 Tenofovir (TFV) gel HIV prevention trial. Detailed 3-month recall data on sex events, condom and gel use were collected from 72 incident cases and 205 uninfected controls. We then assessed how the…
Monitoring Microbicide Gel Use with Real-Time Notification of the Container’s Opening Events
Open AccessTanuja N Gengiah, Michele Upfold et al.ARTICLEAIDS and Behavior2014
The Preventive Misconception
Open AccessRachael Dellar, Rachael C Dellar et al.ARTICLEAIDS and Behavior2014
Impact of an Adherence Intervention on the Effectiveness of Tenofovir Gel in the Caprisa 004 Trial
Open AccessLeila E Mansoor, Quarraisha Abdool Karim et al.ARTICLEAIDS and Behavior2014
Adherence in the Caprisa 004 Tenofovir Gel Microbicide Trial
Open AccessLeila E Mansoor, Quarraisha Abdool Karim et al.ARTICLEAIDS and Behavior2014
Individualised Motivational Counselling to Enhance Adherence to Antiretroviral Therapy is not Superior to Didactic Counselling in South African Patients
Open AccessFrancois van Loggerenberg, Anne D Grant et al.ARTICLEAIDS and Behavior2014
Health-Related Quality of Life Dynamics of HIV-positive South African Women up to ART Initiation
Open AccessAndrew Tomita, Nigel Garrett et al.ARTICLEAIDS and Behavior2013
Health in South Africa
Open AccessBongani M Mayosi, Joy Elizabeth Lawn et al.ARTICLEThe Lancet2012