Ronnie G Gavilán
Biographic Data
| ID | 7983285 |
|---|---|
| NAME | Ronnie G Gavilán |
| GIVEN NAMES | Ronnie G |
| FAMILY NAME | Gavilán |
| SIGNATURE | GAVILÁN R G |
| AFFILIATIONS | Instituto Nacional de Salud |
| ORCID | 0000-0003-1437-5607 |
| VERIFIED | Yes |
| TOTAL WORKS | 9 |
| TOTAL CITATIONS | 0 |
| AUTHOR COUNT | 9 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2011 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 0 |
Development and evaluation of loop-mediated isothermal amplification (Lamp) for rapid detection of Campylobacter jejuni
The LAMP assay based on the cdtC gene is a reliable and rapid method, with high sensitivity and specificity comparable to qPCR for the identification of C. jejuni associated with ADD and GBS, especially in low-resource areas, due to its low cost and ease of implementation
Estandarización y validación de una prueba molecular RT-Lamp in house para el diagnóstico de Sars-CoV-2
The in-house SARS-CoV-2 RT-LAMP test was successfully validated based on its adequate robustness, no cross-reactions, good concordance, and diagnostic performance compared to RT-qPCR
Estructura genética de cepas drogorresistentes de Mycobacterium tuberculosis en Perú basada en haplotipos obtenidos de un ensayo con sondas en línea
Most regions showed high haplotype diversity; in addition, most drug-resistant strains of Mycobacterium tuberculosis were concentrated in the cities of Lima and Callao. Likewise, drug-resistant Mycobacterium tuberculosis strains circulating in Peru mainly contain the genetic markers with the highest prevalence worldwide, which are associated with resistance to rifampicin and isoniazid
Resistoma y genómica comparativa de aislados clínicos de Escherichia coli diarreogénica en Lima, Perú
In order to describe the genomic characteristics related to antimicrobial resistance and comparative genomics of diarrheagenic Escherichia coli (DEC), 14 DEC isolates from the strain collection of the Instituto Nacional de Salud (INS) were subjected to genome sequencing. We used bioinformatic procedures to analyze the obtained sequences in order to look for microbial resistance genes and genetic regions related to pathotypes and phylogroups. Seve…
Diversidad molecular de variantes patogénicas de Vibrio parahaemolyticus en el Perú
During the period from 1995 to 2017, in order to determine the diversity of Vibrio parahaemolyticus pathogenic variants in Peru, 102 Peruvian genomes (97 from a hospital setting and 5 from an out-of-hospital setting) were analyzed using the multilocus typification scheme and BLASTn in the search for virulence genes. Fifteen different sequence types were identified. It was found that the ST3 genotype, which is found in the pandemic clone, was the …
Agentes infecciosos en muestras biológicas de pacientes con síndrome de Guillain-Barré en Perú, 2018-2019
Several pathogens were found in samples from patients with GBS. However, we found that the genotype ST2993 of Campylobacter jejuni was the most likely causal agent, a pathogen that is related to GBS outbreaks in different continents. It is necessary to confirm this hypothesis with additional analytical studies and it is important to describe the transmission mechanism of C. jejuni genotype ST2993 in order to implement prevention and control measu…
Desarrollo y validación del método de amplificación isotérmica mediada en lazo para la detección del virus Zika
A Reverse Transcription Loop-mediated Isothermal Amplification (RT-LAMP) method was developed to detect Zika. The primers were designed based on the NS5 region of 64 complete genomes. Lyophilized LAMP reagent was used. Initially, seven different arboviruses were tested and only Zika samples tested positive. Additionally, serial dilutions of one of Zika's RNA were compared using RT-LAMP and qRT-PCR, demonstrating that RT-LAMP is 1,000 times more s…
Multidrogorresistencia de Salmonella infantis en Perú
Salmonella Infantis has become one of the sero-varieties most frequently referred to the INS, which includes ESBLproducing multidrug-resistant strains with resistance to quinolones. Finally, the relevance of next generation sequencing is reasserted in the characterization of new variants of pathogens that are important for public health, and their potential use in antimicrobial resistance surveillance systems
Factores ambientales vinculados con la aparición y dispersión de las epidemias de Vibrio en América del Sur
Vibrio cholerae and V. parahaemolyticus are the two Vibrio species with a major impact on human health. Diseases caused by both pathogens are acquiring increasing relevance due to their expansion at global scale. In this paper, we resume the ecological aspects associated with the arrival and spreading of infections caused by V. parahaemolyticus and V. cholerae in Peru from a South American perspective. Moreover, we discuss the similarities in the…
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Factores ambientales vinculados con la aparición y dispersión de las epidemias de Vibrio en América del Sur
Vibrio cholerae and V. parahaemolyticus are the two Vibrio species with a major impact on human health. Diseases caused by both pathogens are acquiring increasing relevance due to their expansion at global scale. In this paper, we resume the ecological aspects associated with the arrival and spreading of infections caused by V. parahaemolyticus and V. cholerae in Peru from a South American perspective. Moreover, we discuss the similarities in the…
Desarrollo y validación del método de amplificación isotérmica mediada en lazo para la detección del virus Zika
A Reverse Transcription Loop-mediated Isothermal Amplification (RT-LAMP) method was developed to detect Zika. The primers were designed based on the NS5 region of 64 complete genomes. Lyophilized LAMP reagent was used. Initially, seven different arboviruses were tested and only Zika samples tested positive. Additionally, serial dilutions of one of Zika's RNA were compared using RT-LAMP and qRT-PCR, demonstrating that RT-LAMP is 1,000 times more s…
Multidrogorresistencia de Salmonella infantis en Perú
Salmonella Infantis has become one of the sero-varieties most frequently referred to the INS, which includes ESBLproducing multidrug-resistant strains with resistance to quinolones. Finally, the relevance of next generation sequencing is reasserted in the characterization of new variants of pathogens that are important for public health, and their potential use in antimicrobial resistance surveillance systems
Resistoma y genómica comparativa de aislados clínicos de Escherichia coli diarreogénica en Lima, Perú
In order to describe the genomic characteristics related to antimicrobial resistance and comparative genomics of diarrheagenic Escherichia coli (DEC), 14 DEC isolates from the strain collection of the Instituto Nacional de Salud (INS) were subjected to genome sequencing. We used bioinformatic procedures to analyze the obtained sequences in order to look for microbial resistance genes and genetic regions related to pathotypes and phylogroups. Seve…
Diversidad molecular de variantes patogénicas de Vibrio parahaemolyticus en el Perú
During the period from 1995 to 2017, in order to determine the diversity of Vibrio parahaemolyticus pathogenic variants in Peru, 102 Peruvian genomes (97 from a hospital setting and 5 from an out-of-hospital setting) were analyzed using the multilocus typification scheme and BLASTn in the search for virulence genes. Fifteen different sequence types were identified. It was found that the ST3 genotype, which is found in the pandemic clone, was the …
Agentes infecciosos en muestras biológicas de pacientes con síndrome de Guillain-Barré en Perú, 2018-2019
Several pathogens were found in samples from patients with GBS. However, we found that the genotype ST2993 of Campylobacter jejuni was the most likely causal agent, a pathogen that is related to GBS outbreaks in different continents. It is necessary to confirm this hypothesis with additional analytical studies and it is important to describe the transmission mechanism of C. jejuni genotype ST2993 in order to implement prevention and control measu…
Estandarización y validación de una prueba molecular RT-Lamp in house para el diagnóstico de Sars-CoV-2
The in-house SARS-CoV-2 RT-LAMP test was successfully validated based on its adequate robustness, no cross-reactions, good concordance, and diagnostic performance compared to RT-qPCR
Estructura genética de cepas drogorresistentes de Mycobacterium tuberculosis en Perú basada en haplotipos obtenidos de un ensayo con sondas en línea
Most regions showed high haplotype diversity; in addition, most drug-resistant strains of Mycobacterium tuberculosis were concentrated in the cities of Lima and Callao. Likewise, drug-resistant Mycobacterium tuberculosis strains circulating in Peru mainly contain the genetic markers with the highest prevalence worldwide, which are associated with resistance to rifampicin and isoniazid
Development and evaluation of loop-mediated isothermal amplification (Lamp) for rapid detection of Campylobacter jejuni
The LAMP assay based on the cdtC gene is a reliable and rapid method, with high sensitivity and specificity comparable to qPCR for the identification of C. jejuni associated with ADD and GBS, especially in low-resource areas, due to its low cost and ease of implementation
Biology (7 works) · Genetics (5 works) · Bacteria (4 works) · Medicine (4 works) · Microbiology (4 works) · Genotype (3 works) · Humanities (3 works) · Molecular Biology (3 works) · Vibrio bacteria research studies (3 works) · Virology (3 works)