Aryeh D Stein
Biographic Data
| ID | 89596 |
|---|---|
| NAME | Aryeh D Stein |
| GIVEN NAMES | Aryeh D |
| FAMILY NAME | Stein |
| SIGNATURE | STEIN A D |
| AFFILIATIONS | Emory University |
| ORCID | 0000-0003-1138-6458 |
| VERIFIED | Yes |
| TOTAL WORKS | 76 |
| TOTAL CITATIONS | 189 |
| AUTHOR COUNT | 76 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1993 |
| LATEST PUBLICATION YEAR | 2025 |
| H-INDEX | 5 |
Provision of a liquefied petroleum gas cookstove and fuel during pregnancy and infancy and linear growth trajectories between birth and 12 months
Exposure to particulate pollution from cooking with solid biomass fuels is associated with impaired child linear growth. We examined the effect of a liquefied petroleum gas (LPG) cookstove randomized controlled trial during pregnancy and infancy on linear growth trajectories among infants born to women enrolled during pregnancy. The Household Air Pollution Intervention Network (HAPIN) randomized controlled trial enrolled 3195 pregnant women (9 to…
Worldwide trends in underweight and obesity from 1990 to 2022
BACKGROUND: Underweight and obesity are associated with adverse health outcomes throughout the life course. We estimated the individual and combined prevalence of underweight or thinness and obesity, and their changes, from 1990 to 2022 for adults and school-aged children and adolescents in 200 countries and territories. METHODS: ). For school-aged children and adolescents, we report thinness (BMI 2 SD above the median). FINDINGS: From 1990 to 20…
Women’s health and well-being in five birth cohorts from low- and middle-income countries
Background: Women's health and well-being (WHW) have been receiving growing attention, but limited progress has been made on how to measure its different domains in low- and middle-income countries (LMICs). We used data from five long-term birth cohorts in Brazil, Guatemala, the Philippines and South Africa to explore different domains of adult WHW, and how these domains relate to early life exposures. Methods: Based upon an a priori conceptualis…
Consortium for violence prevention research, leadership training, and implementation for excellence (Converge)
Background: Gender-based violence (GBV) and violence against children (VAC) are two prevalent and highly interconnected global health challenges, yet data and research capacities to study these forms of violence and to generate evidence-based policies and programs remain limited. To address critical shortages in research capacity in Vietnam and to establish a model for other Low- and Middle-Income Countries (LMICs), we are establishing CONVERGE-t…
Early life predictors of body composition trajectories from adolescence to mid‐adulthood
OBJECTIVES: Guatemala has experienced rapid increases in adult obesity. We characterized body composition trajectories from adolescence to mid-adulthood and determined the predictive role of parental characteristics, early life factors, and a nutrition intervention. METHODS: One thousand three hundred and sixty-four individuals who participated as children in a nutrition trial (1969-1977) were followed prospectively. Body composition characterize…
Participation in the Georgia Food for Health programme and CVD risk factors
Objective: To assess the relationship between programme attendance in a produce prescription (PRx) programme and changes in cardiovascular risk factors. Design: The Georgia Food for Health (GF4H) programme provided six monthly nutrition education sessions, six weekly cooking classes and weekly produce vouchers. Participants became programme graduates attending at least 4 of the 6 of both the weekly cooking classes and monthly education sessions. …
Subjective social status is associated with happiness but not weight status or psychological distress
Subjective social status showed small but consistent associations with happiness in birth cohorts independent of life-course SEP
Infant Young Child Feeding Practices in an Indian Maternal–Child Birth Cohort in Belagavi, Karnataka
Poor infant young child feeding (IYCF) practices result in malnutrition, poor psychosocial development, poor school performance and less productivity in later life, thereby perpetuating a vicious cycle. The current study aims to characterize the IYCF practices during the first year of life in a maternal-child birth cohort (DHANI) in Belagavi, Karnataka, India. We collected data from the dyad at birth, 6 and 12 months postpartum. We examined dieta…
Worldwide trends in hypertension prevalence and progress in treatment and control from 1990 to 2019
BACKGROUND: Hypertension can be detected at the primary health-care level and low-cost treatments can effectively control hypertension. We aimed to measure the prevalence of hypertension and progress in its detection, treatment, and control from 1990 to 2019 for 200 countries and territories. METHODS: We used data from 1990 to 2019 on people aged 30-79 years from population-representative studies with measurement of blood pressure and data on blo…
A qualitative study of risks and protective factors against pregnancy among sexually-active adolescents in Soweto, South Africa
Risky sexual behaviors contribute to increased risk of adolescent pregnancy. This qualitative study sought to understand risks and protective factors against pregnancy amongst sexually-active adolescents in Soweto, South Africa. We used purposive sampling to recruit women at age 24 years from Soweto, who self-reported having sexual debut by age 15 years. Twenty women were recruited: (i) women who did not become pregnant before 18 years (n = 10) a…
Socioeconomic position over the life-course and subjective social status in relation to nutritional status and mental health among Guatemalan adults
Subjective social status was independently associated with happiness and psychological distress in middle adulthood after adjusting for objective SEP. Moreover, association of objective SEP with health was not mediated by SSS, suggesting potentially independent pathways
Changes in asset-based wealth across the life course in birth cohorts from five low- and middle-income countries
Temporally-harmonized asset indices displayed coherence with cross-sectional indices as well as construct validity with schooling
Relative and absolute wealth mobility since birth in relation to health and human capital in middle adulthood
Higher attained schooling provided a pathway for upward relative mobility and higher absolute wealth gains as well as protection against downward relative mobility. Upward mobility was associated with lower psychological distress and higher fluid intelligence but also higher weight status
Associations between Free Sugar and Sugary Beverage Intake in Early Childhood and Adult NAFLD in a Population-Based UK Cohort
(1) Background: High sugar intake is prevalent among children and is associated with non-alcoholic fatty liver disease (NAFLD). The purpose of this study is to determine if a high intake of free sugars and sugary beverages (SB) in childhood is associated with NAFLD in adulthood; (2) Methods: At 24 years, 3095 participants were assessed for severe hepatic steatosis (controlled attenuation parameter >280 dB/m) and had dietary data collected via a f…
Cognitive and socio-emotional correlates of psychological well-being and mental health in Guatemalan adults
Of all examined factors, spirituality and religion made the greatest contribution to psychological well-being. These findings support the notion that in populations experiencing difficult circumstances, religion can perhaps make a greater contribution to well-being and aid coping. More research is needed to examine mediators of this association
Portion size and consistency as indicators of complementary food energy intake
We evaluated whether novel portion size and consistency indicators can identify children with low complementary food energy intake in southern Ethiopia. We conducted 24-h dietary recalls with caregivers of 548 children aged 6-13 months; additionally, caregivers estimated their child's usual portion size using uncooked rice and selected which of five photographs of porridges of varying consistencies most closely matched the food their child usuall…
Cabbage and Sauerkraut Consumption in Adolescence and Adulthood and Breast Cancer Risk among US-Resident Polish Migrant Women
Greater consumption of total and raw/short-cooked cabbage/sauerkraut foods either during adolescence or adulthood was associated with significantly reduced BC risk among Polish migrant women. These findings contribute to the growing literature suggesting a protective effect of a potentially modifiable factor, cruciferous vegetable intake, on breast cancer risk
Influence of enhanced nutrition and psychosocial stimulation in early childhood on cognitive functioning and psychological well-being in Guatemalan adults
Our findings suggest that childhood nutrition interventions have long-lasting effects on cognitive ability and psychological well-being outcomes
Height and body-mass index trajectories of school-aged children and adolescents from 1985 to 2019 in 200 countries and territories
BACKGROUND: Comparable global data on health and nutrition of school-aged children and adolescents are scarce. We aimed to estimate age trajectories and time trends in mean height and mean body-mass index (BMI), which measures weight gain beyond what is expected from height gain, for school-aged children and adolescents. METHODS: For this pooled analysis, we used a database of cardiometabolic risk factors collated by the Non-Communicable Disease …
Differential influences of early growth and social factors on young children's cognitive performance in four low-and-middle-income birth cohorts (Brazil, Guatemala, Philippines, and South Africa)
Across four low- and middle-income contexts, cognition in childhood is influenced more by the parental capacity of families and their economic resources than by birth weight and early linear growth. Improving children's cognitive functioning requires multi-sectoral interventions to improve parental education and enhance their economic wellbeing, interventions that are known to improve also early childhood growth
ALT Trends through Childhood and Adolescence Associated with Hepatic Steatosis at 24 Years
(1) Background: Alanine aminotransferase (ALT) is used to screen for non-alcoholic fatty liver disease (NAFLD) in children; however, the optimal age to commence screening is not determined. Our objective was to describe whether ALT trends from 9-24 years were associated with hepatic steatosis at 24 years in a population-based UK cohort. (2) Methods: The sample included 1156 participants who were assessed for hepatic steatosis at 24 years and had …
Rising rural body-mass index is the main driver of the global obesity epidemic in adults
Body-mass index (BMI) has increased steadily in most countries in parallel with a rise in the proportion of the population who live in cities 1,2 . This has led to a widely reported view that urbanization is one of the most important drivers of the global rise in obesity 3–6 . Here we use 2,009 population-based studies, with measurements of height and weight in more than 112 million adults, to report national, regional and global trends in mean B…
Sanitation and diarrhoea in infancy and CRP level at 18 years
Background: Cardiometabolic disease is associated with chronic low-grade inflammation. While low birthweight, childhood stunting and rapid weight gain predict higher adult high-sensitivity C-reactive protein (hs-CRP) concentrations, associations between childhood infections and adulthood CRP are inconsistent.Aim: To assess the associations between sanitation, diarrhoea and a combined score of both from birth to age 2 years and hs-CRP at age 18 ye…
Randomised controlled trial of incentives to improve online survey completion among internet-using men who have sex with men
BACKGROUND: HIV prevention research often involves the use of online surveys as data collection instruments. Incomplete responses to these surveys can introduce bias. We aimed to develop and assess innovative methods to incentivise respondents to complete surveys. METHODS: Adult men who have sex with men (MSM) living in the USA were recruited through banner advertisements on Facebook from 27 April 2015 to 6 May 2015 to participate in an online su…
Worldwide trends in blood pressure from 1975 to 2015
BACKGROUND: Raised blood pressure is an important risk factor for cardiovascular diseases and chronic kidney disease. We estimated worldwide trends in mean systolic and mean diastolic blood pressure, and the prevalence of, and number of people with, raised blood pressure, defined as systolic blood pressure of 140 mm Hg or higher or diastolic blood pressure of 90 mm Hg or higher. METHODS: For this analysis, we pooled national, subnational, or comm…
The Impact of Improving Nutrition During Early Childhood on Education among Guatemalan Adults
Using a longitudinal survey from rural Guatemala, we examine the effect of an early childhood nutritional intervention on adult educational outcomes. An intent-to-treat model yields substantial effects of an experimental intervention that provided highly nutritious food supplements to children, a quarter century after it ended: increases of 1.2 grades completed for women and one quarter SD on standardised reading comprehension and non-verbal cogn…
Periods of child growth up to age 8 years in Ethiopia, India, Peru and Vietnam
Recent research has demonstrated some growth recovery among children stunted in infancy. Less is known about key age ranges for such growth recovery, and what factors are correlates with this growth. This study characterized child growth up to age 1 year, and from ages 1 to 5 and 5 to 8 years controlling for initial height-for-age z-score (HAZ), and identified key distal household and community factors associated with these growth measures using …
The Behavioral Risk Factor Surveillance System questionnaire
The reliability of the Behavioral Risk Factor Surveillance System questionnaire was assessed in a random sample of adults (n = 122) and a separate sample of Black and Hispanic adults (n = 200) in Massachusetts. The questionnaire was administered twice, 21 to 44 days apart, by telephone (210 completed reinterviews, 65% response rate for second administration). There were no statistically significant differences in the distribution of demographic o…
Independent and additive association of prenatal famine exposure and intermediary life conditions with adult mortality between age 18-63 years
In utero exposure to famine and subsequent fertility
OBJECTIVES: We hypothesized that if prenatal caloric restriction due to nutritional deprivation had affected development of the organs responsible for producing and regulating female reproductive hormones, a woman's fertility would be impaired. METHODS: Women born in Amsterdam from August 1, 1944, through April 15, 1946, a period encompassing a severe 5-month famine, were identified (n = 700; 85% response rate). Date of birth and vital status of …
Intergenerational Transmission of Poverty and Inequality
Academic and policy literatures on intergenerational transmissions of poverty and inequality suggest that improving schooling attainment and income for parents in poor households will lessen poverty and inequality in their children’s generation through increased human capital accumulated by their children. However, magnitudes of such effects are unknown. We use data on children born in the twenty-first century in four developing countries to simu…
Influence of enhanced nutrition and psychosocial stimulation in early childhood on cognitive functioning and psychological well-being in Guatemalan adults
Our findings suggest that childhood nutrition interventions have long-lasting effects on cognitive ability and psychological well-being outcomes
Childhood nutrition and later fertility
Better childhood nutrition is associated with earlier physical maturation during adolescence and increased schooling attainment. However, as earlier onset of puberty and increased schooling can have opposing effects on fertility, the net effect of improvements in childhood nutrition on a woman’s fertility are uncertain. Using path analysis, we estimate the strength of the pathways between childhood growth and subsequent fertility outcomes in Guat…
Disability and self-rated health among older women and men in rural Guatemala
Health Status of Children of Migrant Farm Workers
Objectives. We evaluated the health status of migrant farmworkers’ children served by the Farm Worker Family Health Program (FWFHP) in Moultrie, Georgia. Methods. We analyzed data from children aged 0 to 16 years examined through the FWFHP from 2003 to 2011 (n across years = 179–415). We compared their prevalence of overweight, obesity, elevated blood pressure, anemia, and stunting with that of children in the United States and Mexico. Results. A…
Field Lessons From the Delivery of Questionnaires to Young Adults Using Mobile Phones
To examine the feasibility of providing young adults with mobile phones for the purpose of mobile phone–assisted self-interviewing to improve retention in a long-term birth cohort study, mobile phones with survey software were distributed to 1,000 twenty-year-olds in the Birth to Twenty birth cohort study. Eleven months later, a targeted sampling frame was used to randomly select 435 participants from the subset of 734 phones that were still func…
Individual capital and cognitive ageing in Guatemala
Using data from adults 50 years and older in Guatemala (N = 643), we assessed to what extent measures of individual capital-economic, social, intellectual, and biological-were associated with and account for variation in cognitive functioning, as measured by the Modified Mini-Mental Status Exam (M-MMSE). Measures of these components of individual capital are positively associated with cognitive functioning, and together with other attributes, acc…
The Behavioral Risk Factor Surveillance System questionnaire
The reliability of the Behavioral Risk Factor Surveillance System questionnaire was assessed in a random sample of adults (n = 122) and a separate sample of Black and Hispanic adults (n = 200) in Massachusetts. The questionnaire was administered twice, 21 to 44 days apart, by telephone (210 completed reinterviews, 65% response rate for second administration). There were no statistically significant differences in the distribution of demographic o…
Stein and Colleagues Respond
Stein and Colleagues Respond Aryeh D. Stein, Ruth I. Lederman, and Steven Shea L S RobertsonCopyRight https://doi.org/10.2105/AJPH.84.9.1526 Published Online: October 07, 2011
Annotation
Annotation: cause and noncause--nutritional epidemiology and public health nutrition. A D SteinCopyRight https://doi.org/10.2105/AJPH.85.5.618 Published Online: October 07, 2011
In utero exposure to famine and subsequent fertility
OBJECTIVES: We hypothesized that if prenatal caloric restriction due to nutritional deprivation had affected development of the organs responsible for producing and regulating female reproductive hormones, a woman's fertility would be impaired. METHODS: Women born in Amsterdam from August 1, 1944, through April 15, 1946, a period encompassing a severe 5-month famine, were identified (n = 700; 85% response rate). Date of birth and vital status of …
Validation of a semi-quantitative food-frequency questionnaire for use among adults in Guatemala
Objective: The purpose of the study was to assess the validity of a 52-item semiquantitative food-frequency questionnaire (FFQ) by comparing it with multiple 24-hour dietary recalls. Design: Three non-consecutive 24-hour dietary recalls and one FFQ were administered over a one-month period. Setting: Four communities of El Progreso, Guatemala. Subjects: Seventy-three individuals aged 22–55 years. Results: Intakes of energy and other nutrients as m…
Persistent epigenetic differences associated with prenatal exposure to famine in humans
Extensive epidemiologic studies have suggested that adult disease risk is associated with adverse environmental conditions early in development. Although the mechanisms behind these relationships are unclear, an involvement of epigenetic dysregulation has been hypothesized. Here we show that individuals who were prenatally exposed to famine during the Dutch Hunger Winter in 1944–45 had, 6 decades later, less DNA methylation of the imprinted IGF2 …
A fingerprint characteristic associated with the early prenatal environment
Fingerprints and fingertip ridge counts (RCs) have a significant genetic component. However, they also reflect the nongenetic environment of early pregnancy, an important time window for tissue differentiation and organogenesis. Fingerprints are permanently configured before the 20th week of gestation, and each fingertip's RC is related to the growth and regression of its early fetal volar pads. Rostral and caudal aspects of the embryonic limb bu…
Relation of ratio indices of anthropometric measures to obesity in a stunted population
The ratios of anthropometric measures are used to estimate obesity while controlling for allometric scaling. A good index should be uncorrelated with its denominator; this often requires exponentiation of the denominator. The stability of the derived exponents across populations is not known. We obtained subscapular (SUBS) and triceps (TRI) skinfolds, weight (WT), height (HT), waist circumference (WC), fat mass (FM), and fat-free mass (FFM) in a …
Detection of cardio-metabolic risk by BMI and waist circumference among a population of Guatemalan adults
Background BMI and waist circumference (WC) are used to screen for cardio-metabolic risk; however it is unclear how well these indices perform in populations subject to childhood stunting. Objectives To evaluate BMI and WC as indicators of cardio-metabolic risk and to determine optimal cut-off points among 1325 Guatemalan adults (44 % stunted: ≤150 cm women; ≤162 cm men). Methods Cardio-metabolic risk factors were systolic/diastolic blood pressur…
Greater Years of Maternal Schooling and Higher Scores on Academic Achievement Tests are Independently Associated with Improved Management of Child Diarrhea by Rural Guatemalan Mothers
Five-year changes in adiposity and cardio-metabolic risk factors among Guatemalan young adults
Background Rapidly transitioning societies are experiencing dramatic increases in obesity and cardio-metabolic risk; however, few prospective studies from developing countries have quantified these increases or described their joint relationships. Methods We collected dietary, physical activity, demographic, anthropometric and cardio-metabolic risk factor data from 376 Guatemalan young adults in 1997–98 (aged 20–29 years) and in 2002–04 (aged 25–…
The Impact of Improving Nutrition During Early Childhood on Education among Guatemalan Adults
Using a longitudinal survey from rural Guatemala, we examine the effect of an early childhood nutritional intervention on adult educational outcomes. An intent-to-treat model yields substantial effects of an experimental intervention that provided highly nutritious food supplements to children, a quarter century after it ended: increases of 1.2 grades completed for women and one quarter SD on standardised reading comprehension and non-verbal cogn…
Individual capital and cognitive ageing in Guatemala
Using data from adults 50 years and older in Guatemala (N = 643), we assessed to what extent measures of individual capital-economic, social, intellectual, and biological-were associated with and account for variation in cognitive functioning, as measured by the Modified Mini-Mental Status Exam (M-MMSE). Measures of these components of individual capital are positively associated with cognitive functioning, and together with other attributes, acc…
Weight Gain in the First Two Years of Life Is an Important Predictor of Schooling Outcomes in Pooled Analyses from Five Birth Cohorts from Low- and Middle-Income Countries
The 2D
Objectives: Digit lengths, and in particular the ratio of the 2nd (2D) to 4th (4D) digit (2D:4D), are stable in adulthood and have been linked to characteristics thought to have developmental origins, but little research has focused on early life determinants of these measures. We examined whether exposure to acute famine during specific periods of gestation was associated with 2D, 4D or the 2D:4D ratio. Methods: We studied men and women (1) born…
Growth patterns in early childhood and final attained stature
Growth failure is cumulative, and short stature is associated with multiple indices of reduced human capital. Few studies have been able to address in a single analysis both consideration of the timing of growth failure and comparison across populations. We analyzed data from birth cohorts in Brazil, Guatemala, India, the Philippines, and South Africa ( n = 4,659). We used data on length at birth (available for three of the five cohorts), 12 mo, …
Childhood nutrition and later fertility
Better childhood nutrition is associated with earlier physical maturation during adolescence and increased schooling attainment. However, as earlier onset of puberty and increased schooling can have opposing effects on fertility, the net effect of improvements in childhood nutrition on a woman’s fertility are uncertain. Using path analysis, we estimate the strength of the pathways between childhood growth and subsequent fertility outcomes in Guat…
Disability and self-rated health among older women and men in rural Guatemala
Prenatal Famine and Adult Health
We review human studies on the relation between acute exposures to prenatal famine and adult physical and mental health. These studies are observational and include exposures to a famine environment by natural or man-made causes or, more commonly, from the interplay between natural and human factors. These natural experiments provide an opportunity to examine long-term outcomes after famine exposures by comparing exposed and nonexposed individual…
P1-34 Can associations between prenatal nutrition and body mass index be explained by common genetic variants? Findings from the Dutch hunger winter families study
Genome wide association (GWAS) studies have identified single nucleotide polymorphisms (SNPs) related to body mass index (BMI: kg/m 2 ). Associations have also been reported between fetal malnutrition and BMI. We use the circumstances of the Dutch Hunger Winter of 1944–1945 to further examine these relations. We studied 348 adult men and women born in affected cities in the western Netherlands who had been exposed to famine during pregnancy, 294 …
P2-163 Mortality after prenatal exposure to the Dutch famine of 1944–1945
Introduction Some studies have examined long term health effects of famine exposure during pregnancy but little is known about possible effects on adult survival. Methods We selected men with prenatal exposure to the Dutch famine of 1944–1945 from military examinations records (n=408 015) for births 1944–1946 in the Netherlands. We included men exposed in the immediate post-natal period (n=8225) and in the third (n=8197), the second (n=6809), and…
Maternal Prenatal Nutrition and Health in Grandchildren and Subsequent Generations
This review focuses on how maternal prenatal nutritional states may affect the health of grandchildren and later generations. We first summarize the limited current data in human populations relating to the potential transmission of phenotypes across multiple generations that result from the nutritional experience of a pregnant woman. We then discuss findings from other species, especially mammals, that provide important clues as to whether, and …
Birth weight, postnatal weight gain, and adult body composition in five low and middle income countries
OBJECTIVES: To evaluate the associations between birth weight (BW), infancy, and childhood weight gain and adult body composition. METHODS: Subjects included participants of five birth cohort studies from low and middle income nations (Brazil, Guatemala, India, Philippines, and South Africa; n = 3432). We modeled adult body composition as a function of BW and conditional weight gain (CW), representing changes in weight trajectory relative to peer…
Sustainability of market‐based community distribution of S prinkles in western K enya
To evaluate the sustainability of market-based community distribution of micronutrient powders (Sprinkles(®), Hexagon Nutrition, Mumbai, India.) among pre-school children in Kenya, we conducted in August 2010 a follow-up survey, 18 months after study-related marketing and household monitoring ended. We surveyed 849 children aged 6-35 months randomly selected from 60 study villages. Nutritional biomarkers were measured by fingerstick; demographic …
Reliability of Gestational Weight Gain Reported Postpartum
Medicine (69 works) · Demography (57 works) · Environmental health (36 works) · Child Nutrition and Water Access (33 works) · Population (33 works) · Demography (32 works) · Birth, Development, and Health (31 works) · Internal Medicine (23 works) · Psychology (22 works) · Obesity, Physical Activity, Diet (21 works)