Susan E Coffin
Biographic Data
| ID | 9018089 |
|---|---|
| NAME | Susan E Coffin |
| GIVEN NAMES | Susan E |
| FAMILY NAME | Coffin |
| SIGNATURE | COFFIN S E |
| AFFILIATIONS | Children's Hospital of Philadelphia |
| ORCID | 0000-0001-9566-5600 |
| VERIFIED | Yes |
| TOTAL WORKS | 5 |
| TOTAL CITATIONS | 0 |
| AUTHOR COUNT | 5 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 2019 |
| LATEST PUBLICATION YEAR | 2026 |
| H-INDEX | 0 |
Costs and cost-effectiveness of an infection prevention bundle to reduce neonatal sepsis and mortality in Zambia
The Sepsis Prevention in Neonates in Zambia (SPINZ) trial was a prospective observational cohort study conducted in the neonatal intensive care unit of the University Teaching Hospital in Lusaka, Zambia. Introduction of an infection prevention and control (IPC) bundle reduced hospital-associated mortality, total mortality, suspected sepsis, and confirmed bloodstream infections. This companion analysis was undertaken to analyze intervention costs …
Integrated epidemiologic investigation and genomic confirmation of a Klebsiella pneumoniae neonatal sepsis outbreak in Botswana
Klebsiella pneumoniae ( Kpn ) is a major cause of infant mortality worldwide, with most transmission occurring among hospitalized neonates in low- and middle-income countries where infections caused by multidrug-resistant Kpn (MDR- Kpn ) are increasingly common. We hypothesized that integrating laboratory surveillance for neonatal colonization and infection, real-time epidemiologic investigations, and whole-genome sequencing (WGS) could identify …
Transmission dynamics of Klebsiella pneumoniae in a neonatal intensive care unit in Zambia before and after an infection control bundle
Klebsiella pneumoniae is a leading cause of neonatal sepsis in low- and middle-income countries, with antimicrobial resistance (AMR) significantly contributing to mortality. We used whole genome sequencing to explore the impact of an infection prevention and control (IPC) intervention on K. pneumoniae strains and transmission dynamics responsible for sepsis in a Zambian neonatal unit. Blood culture isolates were collected during the Sepsis Preven…
Maternal and neonatal IgG against Klebsiella pneumoniae are associated with lower risk of neonatal sepsis
Sepsis is the leading postnatal cause of neonatal mortality worldwide. Globally Klebsiella pneumoniae is the leading cause of sepsis in hospitalized neonates. This study reports the development and evaluation of an ELISA for anti- Klebsiella IgG using dried blood spot (DBS) samples and evaluates the association of anti- Klebsiella IgG (anti-Kleb IgG) antibodies in maternal and neonatal samples with the risk of neonatal sepsis. Neonates and their …
Saving neonatal lives by improving infection prevention in low-resource units
Infection prevention and control (IPC) are critical for neonatal care in low resource settings, where mortality is high and healthcare-associated infections are common
No prominent works on this page.
Saving neonatal lives by improving infection prevention in low-resource units
Infection prevention and control (IPC) are critical for neonatal care in low resource settings, where mortality is high and healthcare-associated infections are common
Maternal and neonatal IgG against Klebsiella pneumoniae are associated with lower risk of neonatal sepsis
Sepsis is the leading postnatal cause of neonatal mortality worldwide. Globally Klebsiella pneumoniae is the leading cause of sepsis in hospitalized neonates. This study reports the development and evaluation of an ELISA for anti- Klebsiella IgG using dried blood spot (DBS) samples and evaluates the association of anti- Klebsiella IgG (anti-Kleb IgG) antibodies in maternal and neonatal samples with the risk of neonatal sepsis. Neonates and their …
Costs and cost-effectiveness of an infection prevention bundle to reduce neonatal sepsis and mortality in Zambia
The Sepsis Prevention in Neonates in Zambia (SPINZ) trial was a prospective observational cohort study conducted in the neonatal intensive care unit of the University Teaching Hospital in Lusaka, Zambia. Introduction of an infection prevention and control (IPC) bundle reduced hospital-associated mortality, total mortality, suspected sepsis, and confirmed bloodstream infections. This companion analysis was undertaken to analyze intervention costs …
Integrated epidemiologic investigation and genomic confirmation of a Klebsiella pneumoniae neonatal sepsis outbreak in Botswana
Klebsiella pneumoniae ( Kpn ) is a major cause of infant mortality worldwide, with most transmission occurring among hospitalized neonates in low- and middle-income countries where infections caused by multidrug-resistant Kpn (MDR- Kpn ) are increasingly common. We hypothesized that integrating laboratory surveillance for neonatal colonization and infection, real-time epidemiologic investigations, and whole-genome sequencing (WGS) could identify …
Transmission dynamics of Klebsiella pneumoniae in a neonatal intensive care unit in Zambia before and after an infection control bundle
Klebsiella pneumoniae is a leading cause of neonatal sepsis in low- and middle-income countries, with antimicrobial resistance (AMR) significantly contributing to mortality. We used whole genome sequencing to explore the impact of an infection prevention and control (IPC) intervention on K. pneumoniae strains and transmission dynamics responsible for sepsis in a Zambian neonatal unit. Blood culture isolates were collected during the Sepsis Preven…
Neonatal and Maternal Infections (5 works) · Sepsis (4 works) · Klebsiella pneumoniae (3 works) · Neonatal intensive care unit (3 works) · Neonatal sepsis (3 works) · Antibiotic Resistance in Bacteria (2 works) · Biology (2 works) · Infection control (2 works) · Medicine (2 works) · Sepsis Diagnosis and Treatment (2 works)