David Glenn Smith
Biographic Data
| ID | 90835 |
|---|---|
| NAME | David Glenn Smith |
| GIVEN NAMES | David Glenn |
| FAMILY NAME | Smith |
| SIGNATURE | SMITH D G |
| AFFILIATIONS | University of California, Davis |
| ORCID | 0000-0001-7858-3785 |
| VERIFIED | Yes |
| TOTAL WORKS | 105 |
| TOTAL CITATIONS | 396 |
| AUTHOR COUNT | 105 |
| EDITOR COUNT | 0 |
| FIRST PUBLICATION YEAR | 1972 |
| LATEST PUBLICATION YEAR | 2021 |
| H-INDEX | 12 |
Genetic Differentiation Between and Within Northern Native American Language Groups
The National Research Council recommends that genetic differentiation among subgroups of ethnic samples be lower than 3% of the total genetic differentiation within the ethnic sample to be used for estimating reliable random match probabilities for forensic use. Native American samples in the United States' Combined DNA Index System (CODIS) database represent four language families: Algonquian, Na-Dene, Eskimo-Aleut, and Salishan. However, a mini…
Genetic analysis of samples from wild populations opens new perspectives on hybridization between long‐tailed ( Macaca fascicularis ) and rhesus macaques ( Macaca mulatta )
In the past decade, many researchers have published papers about hybridization between long-tailed and rhesus macaques. These previous works have proposed unidirectional gene flow with the Isthmus of Kra as the zoogeographical barrier of hybridization. However, these reports analyzed specimens of unknown origin and/or did not include specimens from Thailand, the center of the proposed area of hybridization. Collected specimens of long-tailed and …
The Microbiome in Posttraumatic Stress Disorder and Trauma-Exposed Controls
OBJECTIVE: Inadequate immunoregulation and elevated inflammation may be risk factors for posttraumatic stress disorder (PTSD), and microbial inputs are important determinants of immunoregulation; however, the association between the gut microbiota and PTSD is unknown. This study investigated the gut microbiome in a South African sample of PTSD-affected individuals and trauma-exposed (TE) controls to identify potential differences in microbial div…
Additional analysis of mtDNA from the Tommy and Mine Canyon sites
Mitochondrial DNA Analysis of Mazahua and Otomi Indigenous Populations from Estado de México Suggests a Distant Common Ancestry
The indigenous Mazahua and Otomi have inhabited the same localities in Estado de México since pre-Columbian times. Their languages, Mazahua and Otomi, belong to the Oto-Manguean linguistic family, and although they share cultural traditions and a regional history that suggest close genetic relationships and common ancestry, the historical records concerning their origin are confusing. To understand the biological relationships between Mazahua and…
Genetic Structure of First Nation Communities in the Pacific Northwest
This study presents genetic data for nine Native American populations from northern North America. Analyses of genetic variation focus on the Pacific Northwest (PNW). Using mitochondrial, Y chromosomal, and autosomal DNA variants, we aimed to more closely address the relationships of geography and language with present genetic diversity among the regional PNW Native American populations. Patterns of genetic diversity exhibited by the three geneti…
An Evaluation of Psychosocial and Religious Belief Differences in a Diverse Racial and Socioeconomic Urban Cancer Population
Performing monkeys of Bangladesh
Genetic Structure of First Nation Communities in the Pacific Northwest
This study presents genetic data for nine Native American populations from northern North America. Analyses of genetic variation focus on the Pacific Northwest (PNW). Using mitochondrial, Y chromosomal, and autosomal DNA variants, we aimed to more closely address the relationships of geography and language with present genetic diversity among the regional PNW Native American populations. Patterns of genetic diversity exhibited by the three geneti…
Population genetics of the California National Primate Research Center’s (CNPRC) captive Callicebus cupreus colony
A Comparison of the Success of Electrophoretic Methods and DNA Fingerprinting for Paternity Testing in Captive Groups of Rhesus Macaques
Genomic evidence for the Pleistocene and recent population history of Native Americans
Genetic history of Native Americans Several theories have been put forth as to the origin and timing of when Native American ancestors entered the Americas. To clarify this controversy, Raghavan et al. examined the genomic variation among ancient and modern individuals from Asia and the Americas. There is no evidence for multiple waves of entry or recurrent gene flow with Asians in northern populations. The earliest migrations occurred no earlier…
An empirical comparison of short tandem repeats (STRs) and single nucleotide polymorphisms (SNPs) for relatedness estimation in Chinese rhesus macaques ( Macaca mulatta )
We compare the effectiveness of short tandem repeat (STR) and single nucleotide polymorphism (SNP) genotypes for estimating pairwise relatedness, using molecular data and pedigree records from a captive Chinese rhesus macaque population at the California National Primate Research Center. We find that a panel of 81 SNPs is as effective at estimating first-order kin relationships as a panel of 14 highly polymorphic STRs. We note, however, that the …
Diversity and molecular phylogeny of mitochondrial DNA of rhesus macaques ( Macaca mulatta ) in Bangladesh
While studies of rhesus macaques (Macaca mulatta) in the eastern (e.g., China) and western (e.g., India) parts of their geographic range have revealed major genetic differences that warrant the recognition of two different subspecies, little is known about genetic characteristics of rhesus macaques in the transitional zone extending from eastern India and Bangladesh through the northern part of Indo-China, the probable original homeland of the sp…
Familial aggregation of chronic diarrhea disease ( CDD ) in rhesus macaques ( M acaca mulatta )
Chronic diarrheal disease (CDD) is a critical problem for breeders of captive rhesus macaque (Macaca mulatta), as it results in significant levels of morbidity and death annually. As with other inflammatory disorders, CDD is thought to be caused by environmental and/or genetic factors. Although correspondence between the characters defined as Mendelian by pedigree or segregation analysis and functional genes is difficult to establish, such analys…
Development and validation of a SNP‐based assay for inferring the genetic ancestry of rhesus macaques ( Macaca mulatta )
Rhesus macaques (Macaca mulatta) are an important primate model species in several areas of biomedical research. The wide geographic distribution of this species has led to significant genetic differentiation among local and regional populations. These regional differences can be important factors in the selection of the most appropriate subjects for particular research studies, as animals from different populations can respond differently to the…
The evolutionary history of SLC6A4 and the role of plasticity in macaca
Serotonin has been repeatedly indicated as a biological marker of behavior. In particular, the serotonin transporter gene, SLC6A4 , has been the focus of a large body of research. Interestingly, both rhesus macaques ( Macaca mulatta ) and humans have independently evolved a number of shared polymorphisms for this gene, which is indicative of parallel evolution between the two species. However, little is known about the evolution of this gene, par…
A genetic comparison of two alleged subspecies of P hilippine cynomolgus macaques
Two subspecies of cynomolgus macaques ( Macaca fascicularis ) are alleged to co‐exist in the Philippines, M. f. philippensis in the north and M. f. fascicularis in the south. However, genetic differences between the cynomolgus macaques in the two regions have never been studied to document the propriety of their subspecies status. We genotyped samples of cynomolgus macaques from Batangas in southwestern Luzon and Zamboanga in southwestern Mindana…
Single‐Nucleotide Polymorphisms Reveal Patterns of Allele Sharing Across the Species Boundary Between Rhesus ( Macaca mulatta ) and Cynomolgus ( M. fascicularis ) Macaques
Both phenotypic and genetic evidence for asymmetric hybridization between rhesus ( Macaca mulatta ) and cynomolgus ( Macaca fascicularis ) macaques has been observed in the region of Indochina where both species are sympatric. The large‐scale sharing of major histocompatibility complex (MHC) class II alleles between the two species in this region supports the hypothesis that genes, and especially genes involved in immune response, are being trans…
Stable dietary isotopes and mtDNA from Woodland period southern Ontario people
Bioarchaeological research must balance scholarly commitment to the generation of new knowledge, descendants' interests in their collective past, and the now common practice of rapid re-interment of excavated human remains. This paper documents the first results of a negotiated protocol built on the retention of one tooth per archaeologically derived skeleton, teeth that can then be used for destructive testing associated with ancient DNA and sta…
Exploring prehistory in the North American southwest with mitochondrial DNA diversity exhibited by Yumans and Athapaskans
A recent study of mitochondrial DNA variation in Native American populations from the American Southwest detected signatures of a population expansion of subhaplogroup B2a, dated to 2,105 years before present (99.5% confidence interval, 1,273–3,773 YBP), following the introduction and intensification of maize agriculture in the region. Only one Yuman group and no Athapaskan speakers were analyzed in previous studies. Here we report mtDNA haplogro…
A Large‐Scale SNP ‐Based Genomic Admixture Analysis of the Captive Rhesus Macaque Colony at the C alifornia N ational P rimate R esearch C enter
Some breeding facilities in the U nited S tates have crossbred C hinese and I ndian rhesus macaque ( M acaca mulatta ) founders either purposefully or inadvertently. Genetic variation that reflects geographic origins among research subjects has the potential to influence experimental outcomes. The use of animals from different geographic regions, their hybrids, and animals of varying degrees of kinship in an experiment can obscure treatment effec…
Population Genetics of the W ashington N ational P rimate R esearch C enter's ( W a NPRC ) Captive Pigtailed Macaque ( Macaca nemestrina ) Population
Pigtailed macaques ( Macaca nemestrina ) provide an important model for biomedical research on human disease and for studying the evolution of primate behavior. The genetic structure of captive populations of pigtailed macaques is not as well described as that of captive rhesus ( M. mulatta) or cynomolgus ( M. fascicularis ) macaques. The W ashington N ational P rimate R esearch C enter houses the largest captive colony of pigtailed macaques loca…
The effect of SNP discovery method and sample size on estimation of population genetic data for Chinese and Indian rhesus macaques (Macaca mulatta)
Genotyping single nucleotide polymorphisms (SNPs) across species in Old World Monkeys
The development of DNA markers is becoming increasingly useful in the field of primatology for studies on paternity, population history, and biomedical research. In this study, we determine the efficacy of using cross‐species amplification to identify single nucleotide polymorphisms (SNPs) in closely related species. The DNA of 93 individuals representing seven Old World Monkey species was analyzed to identify SNPs using cross‐species amplificati…
Genetic analysis of early holocene skeletal remains from Alaska and its implications for the settlement of the Americas
Mitochondrial and Y‐chromosome DNA were analyzed from 10,300‐year‐old human remains excavated from On Your Knees Cave on Prince of Wales Island, Alaska (Site 49‐PET‐408). This individual's mitochondrial DNA (mtDNA) represents the founder haplotype of an additional subhaplogroup of haplogroup D that was brought to the Americas, demonstrating that widely held assumptions about the genetic composition of the earliest Americans are incorrect. The amo…
Distribution of Mitochondrial DNA Lineages among Native American Tribes of Northeastern North America
The mtDNA haplogroups of 185 individuals from Native American tribes in Northeast North America were determined. A subset of these individuals was analyzed by sequencing hypervariable segments I and II of the control region. The haplogroup frequency distributions of populations in the Northeast exhibit regional continuity that predates European contact. A large amount of gene flow has occurred between Siouan-and Algonquian-speaking groups, probab…
Ancient mitochondrial DNA evidence for prehistoric population movement
The mitochondrial DNA of modern Native Americans has been shown to fall into one of at least five haplogroups (A, B, C, D, or X) whose frequencies differ among tribal groups. The frequencies of these five haplogroups in a collection of ancient individuals from Western Nevada dating to between approximately 350–9,200 years BP were determined. These data were used to test the hypothesis, supported by archaeological and linguistic data, that the cur…
Native American mtDNA prehistory in the American Southwest
This study examines the mtDNA diversity of the proposed descendants of the multiethnic Hohokam and Anasazi cultural traditions, as well as Uto‐Aztecan and Southern‐Athapaskan groups, to investigate hypothesized migrations associated with the Southwest region. The mtDNA haplogroups of 117 Native Americans from southwestern North America were determined. The hypervariable segment I (HVSI) portion of the control region of 53 of these individuals was…
Sex Identification of Children Sacrificed to the Ancient Aztec Rain Gods in Tlatelolco
Recent excavations of Temple R, dedicated to the Aztec god of wind and rain, Ehecatl-Quetzalcoatl, at the archaeological site of Tlatelolco, Mexico City, recovered the sacrificial remains of 37 subadults and 6 adults. It is believed that this ceremonial complex was the site of an extraordinary ceremony carried out during the great drought and famine of AD 1454-57, a date consistent with the founding of this temple. The ages of 31 subadults and 1 …
Stable dietary isotopes and mtDNA from Woodland period southern Ontario people
Bioarchaeological research must balance scholarly commitment to the generation of new knowledge, descendants' interests in their collective past, and the now common practice of rapid re-interment of excavated human remains. This paper documents the first results of a negotiated protocol built on the retention of one tooth per archaeologically derived skeleton, teeth that can then be used for destructive testing associated with ancient DNA and sta…
Distribution of Y chromosomes among native North Americans
In this study, 231 Y chromosomes from 12 populations were typed for four diagnostic single nucleotide polymorphisms (SNPs) to determine haplogroup membership and 43 Y chromosomes from three of these populations were typed for eight short tandem repeats (STRs) to determine haplotypes. These data were combined with previously published data, amounting to 724 Y chromosomes from 26 populations in North America, and analyzed to investigate the geograp…
Unexpected patterns of mitochondrial DNA variation among Native Americans from the Southeastern United States
Mitochondrial DNA (mtDNA) haplogroups were determined by restriction fragment length polymorphism‐typing for 66 individuals from four southeastern North American populations, and the HVS I portion of the mtDNA control region was sequenced in 48 of these individuals. Although populations from the same geographic region usually exhibit similar haplogroup frequency distributions (Lorenz and Smith [ 1996 ] Am. J. Phys. Anthropol. 101: 307–323; Malhi …
Migration and Social Structure among the Hopewell
For more than a century, archaeologists have studied the cultural and skeletal remains of the prehistoric Native Americans known as the 'Hopewell Moundbuilders.' While many aspects of the Hopewell phenomenon are now well understood, questions still remain about the genetic makeup, burial practices, and social structure of Hopewell communities. To help answer these questions, we extracted mitochondrial DNA (mtDNA) from the skeletal remains of 39 i…
Repeat silica extraction
Mitochondrial haplogroup M discovered in prehistoric North Americans
Paternity exclusion in six captive groups of rhesus monkeys ( Macaca mulatta )
Five genetic markers were employed to attempt to identify the fathers of 135 Macaca mulatta offspring living in large outdoor field cages. Family studies of two of these markers to confirm mode of inheritance of phenotypes had not heretofore been reported. Of the 284 exclusions required to identify the fathers of all 135 monkeys, 198 (or 70 percent) were possible using only these five genetic polymorphisms. For 58 (or 43 percent) of these 135 off…
Patterns of mtDNA Diversity in Northwestern North America
The mitochondrial DNA (mtDNA) haplogroups of 54 full-blooded modern and 64 ancient Native Americans from northwestern North America were determined. The control regions of 10 modern and 30 ancient individuals were sequenced and compared. Within the Northwest, the frequency distribution for haplogroup A is geographically structured, with haplogroup A decreasing with distance from the Pacific Coast. The haplogroup A distribution suggests that a pre…
Using ancient mtDNA to reconstruct the population history of northeastern North America
Mitochondrial DNA (mtDNA) was extracted and analyzed from the skeletal remains of 44 individuals, representing four prehistoric populations, and compared to that from two other prehistoric and several contemporary Native American populations to investigate biological relationships and demographic history in northeastern North America. The mtDNA haplogroup frequencies of ancient human remains from the Morse (Red Ocher tradition, 2,700 BP) and Oren…
Brief communication
Haplogroup X represents approximately 3% of all modern Native North American mitochondrial lineages. Using RFLP and hypervariable segment I (HVSI) sequence analyses, we identified a prehistoric individual radiocarbon dated to 1,340 ± 40 years BP that is a member of haplogroup X, found near the Columbia River in Vantage, Washington. The presence of haplogroup X in prehistoric North America, along with recent findings of haplogroup X in southern Si…
Exploring prehistory in the North American southwest with mitochondrial DNA diversity exhibited by Yumans and Athapaskans
A recent study of mitochondrial DNA variation in Native American populations from the American Southwest detected signatures of a population expansion of subhaplogroup B2a, dated to 2,105 years before present (99.5% confidence interval, 1,273–3,773 YBP), following the introduction and intensification of maize agriculture in the region. Only one Yuman group and no Athapaskan speakers were analyzed in previous studies. Here we report mtDNA haplogro…
The relationship of the Mimbres to other southwestern and Mexican populations
Ancestral Puebloan mtDNA in context of the greater southwest
The influence of birth timing upon infant growth and survival in Captive Rhesus Macaques (Macaca mulatto)
Ancient DNA Methodology
Distribution of ABO Blood Groups on the Indian Subcontinent
This paper attempts a comprehensive statistical analysis of the O-A-B-AB blood-group frequencies collected from the Indian subcontinent. The objective is to examine the variation in ABO gene frequencies among populations using statistical tests of homogeneity and single-linkage cluster analysis. In all, 899 sets of phenotype frequency data were examined. Of these, 405, each based on a sample of at least 100 individuals and in conformity with Hard…
Mitochondrial DNA and Prehistoric Settlements
We analyzed previously reported mtDNA haplogroup frequencies of 577 individuals and hypervariable segment 1 (HVS1) sequences of 265 individuals from Native American tribes in western North America to test hypotheses regarding the settlement of this region. These data were analyzed to determine whether Hokan and Penutian, two hypothesized ancient linguistic stocks, represent biological units as a result of shared ancestry within these respective g…
Inbreeding in three captive groups of rhesus monkeys
Using electrophoretic and serological genetic markers each of 17 potentially inbred matings in three groups of rhesus monkeys could be classified as either inbred or noninbred matings. Although nine of these 17 matings involved either father‐daughter or paternal half‐sib matings, only 7.4 were expected by chance alone. At least two, and possibly as many as three, of the nine cases of inbreeding involved father‐daughter matings. Thus, no evidence …
Hybridization and Stratification of Nuclear Genetic Variation in Macaca mulatta and M. fascicularis
The Kennewick Skeleton
A human skeleton recovered near Kennewick, Washington, USA in 1996 has been dated to the early Holocene on the basis of multiple radiocarbon determinations, an analysis of a style of a temporally diagnostic projectile point found embedded in the ilium of the skeleton, and geological investigations of the locality where the skeleton was recovered. Based on morphological criteria, the Kennewick skeleton, which is one of the most complete early Holo…
Modernization, Population Dispersion, and Papago Genetic Integrity
The goal of this research paper is the discovery of trends in Papago Indian breeding patterns over the interval of almost a century described by the information collected in the Papago population register. Using time series data, the assumption that breeding patterns conformed to aboriginal forms which prescribed village exogamy and district endogamy is examined and rejected.The unexpected discovery that residents of Papago villages were less clo…
Effect of emigration on the structure and growth of a southwestern Indian reservation population
Methods derived from stable population theory are employed to estimate the effect emigration is exerting upon the capacity of a Southwest Indian reservation population to develop economically. This capacity is measured by age‐structure‐dependent demographic indices which have been shown to affect the availability of development funds. Emigration is found to be absorbing all of the current positive growth of the population, decreasing and aging th…
The effect of sample attrition on the frequency distribution of blood pressure and genetic marker phenotypes representing a natural unselected community
Highly significant differences in mean age, blood pressure and phenotype frequency distributions between the non‐migrants and “emigrants” of a total unselected community sample were discovered. Use of the mean of BP scores collected from epidemiologic surveys over a period of time as an individual score allows sample attrition to produce both a genetically and demographically biased sample of a population intended to represent an unselected commu…
Part four
A social stigma on leprosy has often elicited patterns of positive assortative mating with regard to the presence of the disease in a spouse or in his relatives. Mating patterns were analyzed in a Philippine population in which leprosy has been endemic for over a century. A clear pattern of negative assortative mating was observed after 1915 and became more pronounced through time. Some possible causes and consequences of this mating pattern are …
The genetic hypothesis for the transmission of Australia antigen (HBsAg)
Exceptions have been cited which rule against the simple autosomal recessive hypothesis for the transmission of susceptibility to infection with Australia antigen (HBsAg). An attempt is made here to present a genetic model for a complex segregation analysis of a new and unique set of data to test this hypothesis. Regression techniques were used to estimate in four populations, age and sexspecific penetrance levels and the frequency of the gene wh…
Potential for cumulative inbreeding and its effects upon survival in captive groups of non-human primates
A family study of the hemoglobin polymorphism in Macaca fascicularis
Paternity exclusion in six captive groups of rhesus monkeys ( Macaca mulatta )
Five genetic markers were employed to attempt to identify the fathers of 135 Macaca mulatta offspring living in large outdoor field cages. Family studies of two of these markers to confirm mode of inheritance of phenotypes had not heretofore been reported. Of the 284 exclusions required to identify the fathers of all 135 monkeys, 198 (or 70 percent) were possible using only these five genetic polymorphisms. For 58 (or 43 percent) of these 135 off…
Taste sensitivity to phenylthiourea (PTC) in the rhesus monkey (Macaca mulatta)
The albumin polymorphism and bilirubin binding in rhesus monkeys ( Macaca mulatta )
Family studies confirmed a codominant mode of inheritance of albumin phenotypes identified in Macaca mulatta . Preliminary epidemiological and bilirubin binding studies suggest that selection favors the variant allele by reducing risks of hyperbilirubinemia and might be responsible for this otherwise rare polymorphism
Brief repot
Six mother‐infant pairs in a group of captive rhesus monkeys ( Macaca mulatta ) were observed for six months. “Infant grabs” by others and mothers' resistance to grabs were scored. More full siblings grabbed infants than either paternal half‐siblings or nonrelatives. Mothers resisted grabbing by more nonrelatives than by paternal half‐siblings. Although the maternal effect suggested by full sib‐infant interactions is expected, the paternal effect…
The association between rank and reproductive success of male rhesus monkeys
The paternity of 202 of 220 offspring of rhesus monkeys housed in six separate half‐acre field cages at the California Primate Research Center was determined by genetic marker techniques. Reproductive success of the adult males was statistically significantly correlated (r = 0.76, P
Admixture and population replacement of the sells Papago Indians
Changes in rates of admixture on the Sells Papago Indian reservation over the last century are shown to reflect ethnohistorically recorded events of extra‐tribal contact. Three distinct strategies providing, in varying degrees, for the preservation of group identity were identified. It is argued that strategies favoring maximum preservation of ethnic identity have threatened the survival of the reservation breeding units because traditional patte…
A comparison of the demographic structure and growth of free-ranging and captive groups of rhesus monkeys (Macaca mulatta)
A test of the randomness of paternity of members of maternal sibships in six captive groups of rhesus monkeys (Macaca mulatta)
Segregation distortion at the transferrin locus in Macaca mulatta
The transferrin phenotypes of 256 rhesus monkeys and their parents were identified by polyacrylamide gel electrophoresis. The segregation ratio for phenotypes involving only alleles of high electrophoretic mobility was statistically significantly higher than expected and suggests that selection favors these more negatively charged transferrins. Electrostatic‐dependent processes associated with the binding and transportation of iron might be respo…
Inbreeding in three captive groups of rhesus monkeys
Using electrophoretic and serological genetic markers each of 17 potentially inbred matings in three groups of rhesus monkeys could be classified as either inbred or noninbred matings. Although nine of these 17 matings involved either father‐daughter or paternal half‐sib matings, only 7.4 were expected by chance alone. At least two, and possibly as many as three, of the nine cases of inbreeding involved father‐daughter matings. Thus, no evidence …
Distribution of ABO Blood Groups on the Indian Subcontinent
This paper attempts a comprehensive statistical analysis of the O-A-B-AB blood-group frequencies collected from the Indian subcontinent. The objective is to examine the variation in ABO gene frequencies among populations using statistical tests of homogeneity and single-linkage cluster analysis. In all, 899 sets of phenotype frequency data were examined. Of these, 405, each based on a sample of at least 100 individuals and in conformity with Hard…
Brief report
Peripheral blood samples from 53 macaque perinatal deaths at the California Primate Research Center (CPRC) were cultured to produce chromosomes for analysis. Karyotypes were constructed for 26 successful cultures and revealed no apparent chromosomal anomalies. A genetic screening program at primate breeding facilities is important for estimating the frequency of chromosomal anomalies in macaques and for understanding the contribution of chromosom…
Segregation distortion and differential fitness at the albumin locus in rhesus monkeys ( Macaca mulatta )
The observed patterns of segregation of two co‐dominant alleles at the macaque albumin locus in 400 rhesus monkey offspring were compared with those expected for five segregating mating phenotypes. Rates of reproductive loss and conception were also compared among females of each albumin phenotype. The common albumin allele in macaques, Al A mac , segregated more frequently than expected when the mother was heterozygous but less frequently than e…
High‐resolution chromosomes of rhesus macaques ( Macaca mulatta )
Late‐prophase high‐resolution chromosomes were successfully cultured for 22 of 27 Macaca mulatta samples. Twelve of the successful cultures were adequate for karyotyping high‐resolution spreads. High‐resolution chromosome technique provides an important contribution to primate genetics because it can be used to identify chromosomal anomalies undetected in metaphase spreads and may be useful for paternity exclusion analysis
Social status and reproductive success of male Macaca fascicularis
Dominant males of nonseasonally breeding species should have more opportunity than seasonal breeders to monopolize access to estrous females and thus enhance their reproductive success. They may also use other strategies for maximizing reproductive success such as producing offspring by relatively high ranking females. To test these hypotheses, the paternity of 35 (80%) of 44 Macaca fascicularis offspring, born over a 28‐month period, was establi…
A linkage study of protein‐coding loci in Macaca mulatta and Macaca fascicularis
Genealogical and gene marker data from the closely related species Macaca mulatta and Macaca fascicularis have been used to search for linkage between genes coding for the blood proteins albumin, carbonic anhydrase 1 and 2, diaphorase 1 and 2, group‐specific component, glucose phosphate isomerase, hemoglobin alpha chains, isocitrate dehydrogenase, prealbumin, and transferrin. The results are consistent with conservation of the linkage between the…
Bilirubin binding by the fractionated alternate allelic components of heterozygous monkey albumin
Analysis of bilirubin‐binding parameters for purified albumin of nine rhesus monkeys heterozygous for albumin MacA and albumin MacB was performed after separating these two albumin forms by fast protein liquid chromatography (FPLC). The binding capacity (n) for MacA‐enriched samples was lower than that for the MacB variant in eight of nine fraction pairs analyzed, while the affinity constant (K) was higher in all nine MacA‐enriched samples. The v…
The influence of birth timing upon infant growth and survival in Captive Rhesus Macaques (Macaca mulatto)
Biology (99 works) · Demography (63 works) · Genetics (60 works) · Population (59 works) · Evolutionary biology (50 works) · Gene (50 works) · Genetics (49 works) · Primate Behavior and Ecology (46 works) · Zoology (40 works) · Geography (35 works)