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Preventing Mother-to-Child Transmission of HIV in Resource-Limited Settings

The Elizabeth Glaser Pediatric Aids Foundation Experience

Bibliographic Data

ID11023625
AuthorsAllison Spensley (Allison Spensley, Tabitha Sripipatana, Chuck Hoblitzelle, Joanna Robinson, and Catherine Wilfert are with the Elizabeth Glaser Pediatric AIDS Foundation, Santa Monica, CA. Abigail Norris Turner is with the University of North Carolina, Chapel Hill.), Tabitha Sripipatana (Allison Spensley, Tabitha Sripipatana, Chuck Hoblitzelle, Joanna Robinson, and Catherine Wilfert are with the Elizabeth Glaser Pediatric AIDS Foundation, Santa Monica, CA. Abigail Norris Turner is with the University of North Carolina, Chapel Hill.), Abigail Norris Turner (0000-0003-2463-6399, Allison Spensley, Tabitha Sripipatana, Chuck Hoblitzelle, Joanna Robinson, and Catherine Wilfert are with the Elizabeth Glaser Pediatric AIDS Foundation, Santa Monica, CA. Abigail Norris Turner is with the University of North Carolina, Chapel Hill.), Chuck Hoblitzelle (Allison Spensley, Tabitha Sripipatana, Chuck Hoblitzelle, Joanna Robinson, and Catherine Wilfert are with the Elizabeth Glaser Pediatric AIDS Foundation, Santa Monica, CA. Abigail Norris Turner is with the University of North Carolina, Chapel Hill.), Joanna L Robinson (0000-0002-4416-2330, Allison Spensley, Tabitha Sripipatana, Chuck Hoblitzelle, Joanna Robinson, and Catherine Wilfert are with the Elizabeth Glaser Pediatric AIDS Foundation, Santa Monica, CA. Abigail Norris Turner is with the University of North Carolina, Chapel Hill.), Joanna Robinson (Elizabeth Glaser Pediatric AIDS Foundation), Catherine Wilfert (Allison Spensley, Tabitha Sripipatana, Chuck Hoblitzelle, Joanna Robinson, and Catherine Wilfert are with the Elizabeth Glaser Pediatric AIDS Foundation, Santa Monica, CA. Abigail Norris Turner is with the University of North Carolina, Chapel Hill.), Catherine M Wilfert (Elizabeth Glaser Pediatric AIDS Foundation)
Year2009
Volume99
Issue4
Pages631-637
Publication date2009-04-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueAmerican Journal of Public Health (JOURNAL)
Journal identifiersISSN: 0090-0036 • E-ISSN: 1541-0048
PublisherAmerican Public Health Association (PUBLISHER • US)
DOI10.2105/ajph.2007.114421
PMID18703458
PMCIDPMC2661479
OpenAlexW2088107908
LanguageEN
Citations received6
References cited20

Objectives. In September 1999, the Elizabeth Glaser Pediatric AIDS Foundation initiated a multicountry, service-based programmatic effort in the developing world to reduce perinatally acquired HIV infection. We review 61⁄2 years of one of the world's largest programs for the prevention of mother-to-child transmission (PMTCT) of HIV. Methods. Each PMTCT facility records patient data in antenatal clinics and labor and delivery settings about counseling, testing, HIV status, and antiretroviral prophylaxis and submits the data to foundation staff. Results. More than 2.6 million women have accessed foundation-affiliated services through June 2006. Overall, 92.9% of women who received antenatal care or were eligible for PMTCT services in labor and delivery have been counseled, and 82.8% of those counseled accepted testing. Among women identified as HIV positive, 75.0% received antiretroviral prophylaxis (most a single dose of nevirapine), as did 45.6% of their infants. Conclusions. The foundation's experience has demonstrated that opt-out testing, supplying mothers with medication at time of diagnosis, and providing the infant dose early have measurably improved program efficiency. PMTCT should be viewed as an achievable paradigm and an essential part of the continuum of care

Antiretroviral therapy · Developing country · Family medicine · Human immunodeficiency virus (HIV) · Nevirapine · Transmission (telecommunications) · Viral load · Adolescent Sexual and Reproductive Health · Global Maternal and Child Health · HIV/AIDS Research and Interventions · Medicine · Pediatrics

  • Improving mothers' access to PMTCT programs in West Africa

    Open Access•Philippe Msellati•Social Science & Medicine•2009

  • Scaling up prevention of mother-to-child HIV transmission programs in sub-Saharan African countries

    Open Access•Étienne Audureau, James G Kahn et al.•BMC Public Health•2013

  • Prevention of mother-to-child HIV transmission in resource-limited settings

    Open Access•Joel Ladner, Marie-Hélène Besson et al.•BMC Public Health•2013

  • Barriers to initiating antiretroviral therapy during pregnancy

    Kathryn Stinson, Landon Myers•African Journal of AIDS Research•2012

  • Factors influencing utilization of postpartum CD4 count testing by HIV-positive women not yet eligible for antiretroviral treatment

    Kate Gilles, Kate P Gilles et al.•AIDS Care•2011

  • Factors affecting adherence to short-course ARV prophylaxis for preventing mother-to-child transmission of HIV in sub-Saharan Africa

    M Colombini, Heidi Stöckl et al.•AIDS Care•2014

  • Intrapartum and neonatal single-dose nevirapine compared with zidovudine for prevention of mother-to-child transmission of HIV-1 in Kampala, Uganda

    Open Access•Laura Guay, Laura A Guay et al.•The Lancet•1999

Unique citing works6
Citations per year0,35
Citation span2009 - 2014 (6)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 5
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