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UPLC-QTOF-MS identification of metabolites in rat biosamples after oral administration of Dioscorea saponins

A comparative study

Bibliographic Data

ID14736664
AuthorsYi-Na Tang, Yina Tang (0000-0003-1497-8213, Hong Kong Baptist University), Yu-Xin Pang, Yuxin Pang (0000-0003-3186-4293, Tropical Crops Genetic Resources Institute), Xi-Cheng He (Hong Kong Baptist University), Ya-Zhou Zhang, Yazhou Zhang (0000-0002-5699-0176, Hong Kong Baptist University), Jianye Zhang (0000-0002-9579-1399, Hong Kong Baptist University), Jian-Ye Zhang, Zhong-zhen Zhao (0000-0002-6533-9668, Hong Kong Baptist University), Tao Yi (0000-0003-0045-2202, Hong Kong Baptist University, corresponding author), Hu-Biao Chen, Hubiao Chen (0000-0003-0708-6073, Hong Kong Baptist University, corresponding author)
Year2015
Volume165
Pages127-140
Publication date2015-05-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Ethnopharmacology (JOURNAL)
Journal identifiersISSN: 0378-8741 • E-ISSN: 1872-7573
PublisherElsevier BV (PUBLISHER)
DOI10.1016/j.jep.2015.02.017
PMID25698242
OpenAlexW1997240658
LanguageEN
Citations received9
References cited17

Chromatography · Dioscorea · Diosgenin · Glycoside · High-performance liquid chromatography · Medicinal plants · Oral administration · Pharmacokinetics · Saponin · Stereochemistry · Traditional medicine · Urine · Chemistry · Chromatography in Natural Products · Medicine · Phytochemical Studies and Bioactivities · Phytochemistry and Bioactive Compounds · Biochemistry · Pharmacology

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    Open Access•Yinghuan Hu, Chengyu Wang et al.•Journal of Ethnopharmacology•2023

  • Dioscorea zingiberensis C. H. Wright

    Open Access•Xinxin Zhang, Ming Jin et al.•Journal of Ethnopharmacology•2018

  • Effect and mechanism of dioscin from Dioscorea spongiosa on uric acid excretion in animal model of hyperuricemia

    Open Access•Yi Zhang, Lijun Jin et al.•Journal of Ethnopharmacology•2018

  • Metabolite profiling and evaluation of CYP450 interaction potential of ‘Trimada’- an Ayurvedic formulation

    Open Access•Amit Kar, Pulok Kumar Mukherjee et al.•Journal of Ethnopharmacology•2021

  • Yinchen gongying decoction mitigates CCl4-induced chronic liver injury and fibrosis in mice implicated in inhibition of the FoxO1/TGF-β1/ Smad2/3 and YAP signaling pathways

    Open Access•Xinyi Feng, Hengxu Liu et al.•Journal of Ethnopharmacology•2024

  • Effects of total saponins from Trillium tschonoskii rhizome on grey and white matter injury evaluated by quantitative multiparametric MRI in a rat model of ischemic stroke

    Open Access•Man-zhong Li, Manzhong Li et al.•Journal of Ethnopharmacology•2018

  • In vivo and in vitro study on the regulatory mechanism of XiaoChaiHu decoction on PANoptosis in sepsis-induced cardiomyopathy

    Open Access•Yaru Wang, Xingxing Fu et al.•Journal of Ethnopharmacology•2025

  • Cardioprotective effect of total saponins from three medicinal species of Dioscorea against isoprenaline-induced myocardial ischemia

    Open Access•Yi-Na Tang, Yina Tang et al.•Journal of Ethnopharmacology•2015

  • Antiproliferative and antitumour activity of saponins from Astragalus glycyphyllos on myeloid Graffi tumour

    Open Access•Ani Georgieva, G Popov et al.•Journal of Ethnopharmacology•2021

  • Acute toxicity and sub-chronic toxicity of steroidal saponins from Dioscorea zingiberensis C.H.Wright in rodents

    Open Access•Yuan Qin, Qin Yuan et al.•Journal of Ethnopharmacology•2009

  • An integrated strategy based on UPLC–DAD–QTOF-MS for metabolism and pharmacokinetic studies of herbal medicines

    Open Access•Tao Yi, Lin Zhu et al.•Journal of Ethnopharmacology•2014

  • Trillin, a steroidal saponin isolated from the rhizomes of Dioscorea nipponica, exerts protective effects against hyperlipidemia and oxidative stress

    Open Access•Tiejie Wang, Roy C Y Choi et al.•Journal of Ethnopharmacology•2012

Unique citing works9
Citations per year0,82
Citation span2015 - 2025 (11)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 9
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