Accuracy and Acceptability of Oral Fluid HIV Self-Testing in a General Adult Population in Kenya
Bibliographic Data
| ID | 15337633 |
|---|---|
| Authors | Ann Kurth (0000-0003-2300-6723, corresponding author), Ann E Kurth, Charles M Cleland (0000-0002-6931-9904, New York University), Nok Chhun (0000-0001-5998-3839, New York University), John E Sidle (Indiana University – Purdue University Indianapolis), Edwin Were (0000-0002-4783-0795, Moi University), Violet Naanyu (0000-0003-0182-1719, AMPATH), Wilfred Emonyi (0000-0001-8027-0585, AMPATH), Stephen Macharia (Moi University), Stephen M Macharia, Edwin Sang (AMPATH), Abraham Siika (0000-0001-7669-6612, Moi University), Abraham M Siika |
| Year | 2015 |
| Volume | 20 |
| Issue | 4 |
| Pages | 870-879 |
| Publication date | 2015-10-05 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | AIDS and Behavior (JOURNAL) |
| Journal identifiers | ISSN: 1090-7165 • E-ISSN: 1573-3254 |
| Publisher | Springer Science+Business Media (PUBLISHER • DE) |
| DOI | 10.1007/s10461-015-1213-9 |
| PMID | 26438487 |
| OpenAlex | W1867571570 |
| Language | EN |
| Citations received | 28 |
| References cited | 21 |
We evaluated performance, accuracy, and acceptability parameters of unsupervised oral fluid (OF) HIV self-testing (HIVST) in a general population in western Kenya. In a prospective validation design, we enrolled 240 adults to perform rapid OF HIVST and compared results to staff administered OF and rapid fingerstick tests. All reactive, discrepant, and a proportion of negative results were confirmed with lab ELISA. Twenty participants were video-recorded conducting self-testing. All participants completed a staff administered survey before and after HIVST to assess attitudes towards OF HIVST acceptability. HIV prevalence was 14.6 %. Thirty-six of the 239 HIVSTs were invalid (15.1 %; 95 % CI 11.1-20.1 %), with males twice as likely to have invalid results as females. HIVST sensitivity was 89.7 % (95 % CI 73-98 %) and specificity was 98 % (95 % CI 89-99 %). Although sensitivity was somewhat lower than expected, there is clear interest in, and high acceptability (94 %) of OF HIV self-testing
Environmental health · Family medicine · Fingerstick · Health psychology · Human immunodeficiency virus (HIV · Pathology · Population · Public health · HIV Research and Treatment · HIV/AIDS oral health manifestations · HIV/AIDS Research and Interventions · Medicine · Internal Medicine
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| Unique citing works | 28 |
|---|---|
| Citations per year | 2,8 |
| Citation span | 2016 - 2025 (10) |
| Citation velocity | recent |
| Highly cited | No |
| Citation types | Neutral: 28 |