Physical, Emotional, and Psychosocial Challenges Associated with Daily Dosing of HIV Medications and Their Impact on Indicators of Quality of Life
Findings from the Positive Perspectives Study
Bibliographic Data
| ID | 15339086 |
|---|---|
| Authors | Patricia Ríos (0000-0003-2599-282X, corresponding author), Patricia de los Rios, Chinyere Okoli (0000-0002-9424-2873, ViiV Healthcare (United Kingdom)), Erika Castellanos (Central America Health Sciences University), Brent Allan (0000-0001-9964-3564, International Council Of Aids Service Organizations), Benjamin Young (0000-0003-1606-3367, Triangle), Garry Brough, Marvelous Muchenje, Anton Eremin (0000-0001-6232-1764, Regional Research Centres), Giulio Maria Corbelli (0000-0001-5246-7161), Marta McBritton, William D Hardy (0000-0001-8948-9524, Johns Hopkins University), Nicolas Van de Velde (0000-0003-4358-5873, ViiV Healthcare (United Kingdom)) |
| Year | 2020 |
| Volume | 25 |
| Issue | 3 |
| Pages | 961-972 |
| Publication date | 2020-10-07 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | AIDS and Behavior (JOURNAL) |
| Journal identifiers | ISSN: 1090-7165 • E-ISSN: 1573-3254 |
| Publisher | Springer Science+Business Media (PUBLISHER • DE) |
| DOI | 10.1007/s10461-020-03055-1 |
| PMID | 33026574 |
| OpenAlex | W3091817640 |
| Language | EN |
| Citations received | 10 |
| References cited | 41 |
To assess challenges with daily oral antiretroviral therapy (ART), we analyzed data for 2389 participants in the 2019 Positive Perspectives survey of people living with HIV in 25 countries. ART-related challenges reported included difficulty swallowing pills (33.1% [790/2389]); stress from daily dosing routine (33.3% [795/2389]); bad memories from daily intake of HIV medication (35.1%[839/2389]), and concern "that having to take pills every day means a greater chance of revealing my HIV status to others" (37.9% [906/2389]). Individuals who felt empowered by daily oral dosing ["taking my pill(s) every day reassures me that my HIV is being kept under control"] had 69% higher odds of optimal overall health (AOR 1.69, 95% CI 1.40-2.04). Conversely, odds of optimal overall health were lower among those who felt daily pill intake "limits my day-to-day life" (AOR 0.53, 95% CI 0.44-0.64). These findings show that there is need for increased flexibility of ART delivery to meet diverse patient needs
Dosing · Family medicine · Health psychology · Logistic regression · Odds · Odds ratio · Pill · Psychiatry · Psychosocial · Public health · Quality of life (healthcare · HIV Research and Treatment · HIV-related health complications and treatments · HIV/AIDS Research and Interventions · Medicine · Nursing · Gerontology · Internal Medicine · Pharmacology
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| Unique citing works | 10 |
|---|---|
| Citations per year | 2 |
| Citation span | 2021 - 2026 (6) |
| Citation velocity | current |
| Highly cited | No |
| Citation types | Neutral: 8 |