Estimating the Burden of Stroke

Two-Year Societal Costs and Generic Health-Related Quality of Life of the Restore4Stroke Cohort

Bibliographic Data

ID15469419
AuthorsGhislaine van Mastrigt (0000-0001-8053-5512, Maastricht University, corresponding author), Caroline van Heugten (0000-0003-4272-7315, Maastricht University), Anne Visser‐Meily (University Medical Center Utrecht), Anne Visser-Meily (Department of Rehabilitation, Physical Therapy Science and Sports, Brain Center, University Medical Center Utrecht, 3584 CX Utrecht, The Netherlands), Leonarda G M Bremmers (0000-0003-0569-397X, Erasmus University Rotterdam), Sandra Ever (0000-0003-1026-570X, Maastricht University), Silvia Evers (Maastricht University)
Year2022
Volume19
Issue17
Pages11110-11110
Publication date2022-09-05
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueInternational Journal of Environmental Research and Public Health (JOURNAL)
Journal identifiersISSN: 1661-7827 • E-ISSN: 1660-4601
PublisherMultidisciplinary Digital Publishing Institute (PUBLISHER • CH)
DOI10.3390/ijerph191711110
PMID36078828
OpenAlexW4294739760
LanguageEN
Citations received1
References cited48

(1) Background: This study aimed to investigate two-year societal costs and generic health-related quality of life (QoL) using a bottom-up approach for the Restore4Stroke Cohort. (2) Methods: Adult post-stroke patients were recruited from stroke units throughout the Netherlands. The societal costs were calculated for healthcare and non-healthcare costs in the first two years after stroke. The QoL was measured using EQ-5D-3L. The differences between (sub)groups over time were investigated using a non-parametric bootstrapping method. (3) Results: A total of 344 post-stroke patients were included. The total two-year societal costs of a post-stroke were EUR 47,502 (standard deviation (SD = EUR 2628)). The healthcare costs decreased by two thirds in the second year -EUR 14,277 (95% confidence interval -EUR 17,319, -EUR 11,236). In the second year, over 50% of the total societal costs were connected to non-healthcare costs (such as informal care, paid help, and the inability to perform unpaid labor). Sensitivity analyses confirmed the importance of including non-healthcare costs for long-term follow-up. The subgroup analyses showed that patients who did not return home after discharge, and those with moderate to severe stroke symptoms, incurred significantly more costs compared to patients who went directly home and those who reported fewer symptoms. QoL was stable over time except for the stroke patients over 75 years of age, where a significant and clinically meaningful decrease in QoL over time was observed. (4) Conclusions: The non-healthcare costs have a substantial impact on the first- and second-year total societal costs post-stroke. Therefore, to obtain a complete picture of all the relevant costs related to a stroke, a societal perspective with a follow-up of at least two years is highly recommended. Additionally, more research is needed to investigate the decline in QoL found in stroke patients above the age of 75 years

Bootstrapping (finance · Cohort · Cohort study · Confidence interval · Cost effectiveness · Health care · Indirect costs · Physical therapy · Quality of life (healthcare · Quality-adjusted life year · Stroke (engine · Total cost · Acute Ischemic Stroke Management · Demography · Health Systems, Economic Evaluations, Quality of Life · Medicine · Nursing · Stroke Rehabilitation and Recovery · Finance · Gerontology · Internal Medicine