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Achieving pregnancy safely

Perspectives on timed vaginal insemination among HIV-serodiscordant couples and health-care providers in Kisumu, Kenya

Bibliographic Data

ID19440200
AuthorsOkeoma Mmeje (0000-0001-5460-4932, University of Michigan, corresponding author), Sheryl van der Poel (World Health Organization), Meklit Workneh (0000-0002-9974-2340, Johns Hopkins University), Betty Njoroge (Centre for Microbiology Research, Kenya Medical Research Institute (KEMRI), Nairobi, Kenya), Elizabeth A Bukusi (0000-0002-2031-2808, Kenya Medical Research Institute), Elizabeth Bukusi (Centre for Microbiology Research, Kenya Medical Research Institute (KEMRI), Nairobi, Kenya), Craig R Cohen (0000-0001-8654-6634, Family AIDS Care and Education Services (FACES), Nairobi, Kenya)
Year2015
Volume27
Issue1
Pages10-16
Publication date2015-01-02
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueAIDS Care (JOURNAL)
Journal identifiersISSN: 0954-0121 • E-ISSN: 1360-0451
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/09540121.2014.946385
PMID25105422
PMCIDPMC4221525
OpenAlexW2063534432
LanguageEN
Citations received10
References cited7

In female-positive HIV-serodiscordant couples desiring children, home timed vaginal insemination (TVI) of semen during the fertile period along with consistent condom use may reduce the risk of HIV transmission when the man is HIV-uninfected. In sub-Saharan Africa, up to 45% of HIV-infected women desire to have more children. HIV viral load assessment is not routinely available in low-resource countries for monitoring adherence and response to antiretroviral therapy. Therefore, in these settings, timed unprotected intercourse without assurance of HIV viral suppression may pose unnecessary risks. TVI, a simple and affordable intervention, can be considered an adjunct method and option of safer conception for HIV prevention with treatment of the HIV-infected partner and/or pre-exposure prophylaxis. We conducted five mixed and single-sex focus group discussions comprised of 33 HIV-serodiscordant couples and health-care providers in the Nyanza region of Kenya to assess the acceptability and feasibility of TVI as a safer method of conception. The transcribed data were analyzed using a grounded theory approach. We found that educating and counseling HIV-serodiscordant couples on TVI could make it an acceptable and feasible safer conception method when associated with frequent communication and home visits by health-care providers. The findings of this study indicate that implementation studies that integrate training and counseling of HIV-serodiscordant couples and health-care providers on TVI combined with consistent condom use are needed. Acknowledging and supporting the reproductive choice and needs of female positive, male negative HIV-serodiscordant couples who desire children should also include the use of assisted reproductive services at the same time as pharmaceutical options that prevent sexual HIV transmission

Antiretroviral therapy · Condom · Environmental health · Family medicine · Gynecology · Health care · Obstetrics · Population · Pregnancy · Reproductive health · Serodiscordant · Viral load · Adolescent Sexual and Reproductive Health · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · Medicine · Nursing

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  • New heterosexually transmitted HIV infections in married or cohabiting couples in urban Zambia and Rwanda

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Unique citing works10
Citations per year0,91
Citation span2015 - 2026 (12)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 9
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