Prevalence and risk factors associated with syphilis in a cohort of HIV positive individuals in Brazil
Bibliographic Data
| ID | 19441864 |
|---|---|
| Authors | Rafael Adolf (0000-0002-8456-7164, Universidade Federal do Rio Grande do Sul), Fabien Bercht (Universidade Federal do Rio Grande do Sul), Maria Luisa Aronis (Hospital de Clínicas de Porto Alegre), Luciano Werle Lunardi (0000-0002-6269-2212, Hospital de Clínicas de Porto Alegre), Mauro Schechter (0000-0003-2362-9170, Universidade Federal do Rio de Janeiro), Eduardo Sprinz (0000-0003-4343-8304, Universidade Federal do Rio Grande do Sul, corresponding author) |
| Year | 2012 |
| Volume | 24 |
| Issue | 2 |
| Pages | 252-258 |
| Publication date | 2012-02-01 |
| Peer Reviewed | Yes |
| Open Access | No |
| Type | ARTICLE |
| Venue | AIDS Care (JOURNAL) |
| Journal identifiers | ISSN: 0954-0121 • E-ISSN: 1360-0451 |
| Publisher | Informa UK Limited (PUBLISHER • GB) |
| DOI | 10.1080/09540121.2011.597706 |
| PMID | 21780954 |
| OpenAlex | W2029996623 |
| Language | EN |
| Citations received | 4 |
| References cited | 24 |
Individuals with syphilis have higher chance of having HIV, and syphilis' genital ulcers increases HIV transmission rate. Nevertheless, there are few well-documented studies about HIV and syphilis co-infection and its risk factors. The study was based on 2262 HIV infected individuals from South Brazilian HIV cohort, which began in 1991, and this analysis included individuals who were included in the cohort until November 2008. Inclusion criteria were having CD4 + T cell count and viral load at baseline, and syphilis serology tests (venereal disease research laboratory [VDRL] > 1:64 or a positive VDRL plus a positive treponemal test). A total of 1012 patients were included; 580 were men (57%); mean age at HIV diagnosis was 33 years; 591 (58%) had previous diagnosis of AIDS; most of the individuals acquired HIV from sexual contact (47.9% heterosexual and 31.7% men who had sex with men [MSM]); and 759 (75%) were on antiretroviral therapy. The prevalence of syphilis was 20.5% (208). After multivariate analysis, being male (2.01; 95% CI, 1.23-3.27; p = 0.005) and MSM (1.91; 95% CI, 1.25-2.90; p = 0.002) were significantly associated to HIV and syphilis co-infection. Males and MSM were associated with higher risk of this co-infection. Our findings may reflect that this particular population is still engaging in unprotected sexual intercourse, and efforts should be made to better target this specific group as they might perpetuate these infections
Antibody · Cohort · Cohort study · Environmental health · Men who have sex with men · Population · Serology · Sexually transmitted disease · Syphilis · Demography · HIV/AIDS Research and Interventions · Medicine · Sex work and related issues · Syphilis Diagnosis and Treatment · Immunology · Internal Medicine
Prevalence and Factors Associated With Syphilis in People Living With HIV/Aids in the State of Pará, Northern Brazil
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Syphilis and HIV Co-Infection in Patients Who Attend an Aids Outpatient Clinic in Vitoria, Brazil
The Intersection of HIV, Social Vulnerability, and Reproductive Health
| Unique citing works | 4 |
|---|---|
| Citations per year | 0,31 |
| Citation span | 2013 - 2022 (10) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 4 |