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Assessing the association between self-report items for HIV pill adherence and biological measures

Bibliographic Data

ID19444161
AuthorsAshraf Kagee (0000-0003-1241-2566, Stellenbosch University, corresponding author), Adriaan Nel (Stellenbosch University)
Year2012
Volume24
Issue11
Pages1448-1452
Publication date2012-11-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueAIDS Care (JOURNAL)
Journal identifiersISSN: 0954-0121 • E-ISSN: 1360-0451
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/09540121.2012.687816
PMID22670758
OpenAlexW2053899556
LanguageEN
Citations received12
References cited13

Sub-optimal pill adherence to antiretroviral treatment among HIV-infected persons may have serious consequences, including a decline in health status, eventually leading to death. We developed an instrument to assess self-reported pill adherence to antiretroviral therapy (ART) among patients attending a public health clinic in South Africa. The instrument, based on previously published guidelines, consisted of five questions and a visual analogue scale assessing pill adherence behaviour and was administered to 101 patients living with HIV who commenced ART at least six months prior to data collection. The scale showed fair but not excellent internal consistency (alpha reliability=0.63). Participants reported generally high levels of pill adherence. One question on the scale was able to distinguish between a detectable and a lower than detectable viral load (p<0.01). Yet, the combined items did not predict biologically measured adherence. Despite good comprehensibility of items, the study may have been vulnerable to recall and social desirability bias and was conducted only among clinic attenders rather than those with varied levels of clinic attendance, which is potentially a matter for further study

Antiretroviral medication · Antiretroviral therapy · Attendance · Family medicine · Internal consistency · Medical prescription · Pill · Psychometrics · Recall · Viral load · Clinical Psychology · HIV, Drug Use, Sexual Risk · HIV/AIDS Research and Interventions · LGBTQ Health, Identity, and Policy · Medicine · Nursing · Psychology

  • Health Literacy and Demographic Disparities in HIV Care Continuum Outcomes

    Open Access•Peter F Rebeiro, Tristan D McPherson et al.•AIDS and Behavior•2018

  • Feasibility and Acceptability of Real-Time Antiretroviral Adherence Monitoring among Depressed Women Living with HIV in the Deep South of the US

    Open Access•Kristi L Stringer, Andres Azuero et al.•AIDS and Behavior•2018

  • A Self-Reported Adherence Measure to Screen for Elevated HIV Viral Load in Pregnant and Postpartum Women on Antiretroviral Therapy

    Open Access•Tamsin K Phillips, Tamsin Phillips et al.•AIDS and Behavior•2016

  • Behavioral Intervention Improves Treatment Outcomes Among HIV-Infected Individuals Who Have Delayed, Declined, or Discontinued Antiretroviral Therapy

    Open Access•The Heart to Heart Collaborative Research Team, Marya Gwadz et al.•AIDS and Behavior•2015

  • What’s in Your Dataset? Measuring Engagement in HIV Care Using Routinely Administered Items with a Population Disproportionately Burdened by HIV

    Open Access•Wilson Vincent, Daniel E Siconolfi et al.•AIDS and Behavior•2023

  • Measuring ART Adherence Among Young Adults with Perinatally Acquired HIV

    Open Access•Reuben N Robbins, Luke Kluisza et al.•AIDS and Behavior•2023

  • Moving Antiretroviral Adherence Assessments to the Modern Era

    Open Access•Parya Saberi, Deepalika Chakravarty et al.•AIDS and Behavior•2019

  • Unannounced Telephone-Based Pill Counts

    Open Access•Rob Jay Fredericksen, R Fredericksen et al.•AIDS and Behavior•2014

  • Utility of Different Adherence Measures for PrEP

    Open Access•Andrew Abaasa, Craig W Hendrix et al.•AIDS and Behavior•2017

  • Randomized Controlled Trial of Automated Directly Observed Therapy for Measurement and Support of PrEP Adherence Among Young Men Who have Sex with Men

    Open Access•Susan Buchbinder, Aaron J Siegler et al.•AIDS and Behavior•2022

  • Does past depression predict present depression among HIV test-seekers

    Christo van der Bank, Ashraf Kagee•AIDS Care•2022

  • Relationship between depressive symptoms, alcohol use, and antiretroviral therapy adherence among HIV-infected, clinic-attending patients in South Africa

    Open Access•Jessica F Magidson, Wylene Saal et al.•Journal of Health Psychology•2017

  • Self-Report Measures of Antiretroviral Therapy Adherence

    Open Access•Jane M Simoni, Ann E Kurth et al.•AIDS and Behavior•2006

  • Adherence to protease inhibitors, HIV-1 viral load, and development of drug resistance in an indigent population

    David R Bangsberg, FREDERICK HECHT et al.•AIDS•2000

  • Quality of life in HIV-infected individuals receiving antiretroviral therapy is related to adherence

    Sharon Mannheimer, S B Mannheimer et al.•AIDS Care•2005

  • Comparing Objective Measures of Adherence to HIV Antiretroviral Therapy

    Open Access•David R Bangsberg, FREDERICK HECHT et al.•AIDS and Behavior•2001

Unique citing works12
Citations per year1
Citation span2014 - 2023 (10)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 12
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