Cognitive Functioning and Its Stability Among Young Adults with Perinatal HIV Exposure or Acquisition in a U.S.-Based Longitudinal Cohort Study

Bibliographic Data

ID19469765
AuthorsSharon Nichols (0000-0002-2838-8268, University of California San Diego, corresponding author), Yanling Huo (Cancer Research And Biostatistics), Patricia A Garvie (0000-0003-4703-0808, University of Fort Lauderdale), Sara Caniglia (Cancer Research And Biostatistics), Renée Smith, R Kevin Smith (University of Illinois Chicago), Kathleen Malee (0000-0002-6384-1283, Northwestern University), Megan S McHenry (0000-0001-6753-0928, Indiana University School of Medicine), Mary E Paul (0000-0002-6885-2838, Baylor College of Medicine), Anna-Barbara Moscicki (University of California, Los Angeles), Guadalupe Morales Avendano (University of Southern California), Katherine Tassiopoulos (0000-0003-4773-2535, Cancer Research And Biostatistics), Megan Wilkins (0009-0007-8520-6292, St. Jude Children's Research Hospital), Megan L Wilkins (St. Jude Children's Research Hospital), Claire Berman (0000-0001-5719-8482, Harvard University), Claire A Berman, Paige L Williams (0000-0002-7160-574X, Harvard University)
Year2026
Publication date2026-06-02
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAIDS and Behavior (JOURNAL)
Journal identifiersISSN: 1090-7165 • E-ISSN: 1573-3254
PublisherSpringer Science and Business Media LLC (PUBLISHER)
DOI10.1007/s10461-026-05133-2
PMID42228346
OpenAlexW7163185234
LanguageEN
References cited61

The growing population of young adults with perinatal HIV acquisition (YAPHIV) or exposure without acquisition (YAPHEU) warrants investigation of ongoing cognitive effects of PHIV and lasting neurodevelopmental consequences of perinatal exposure to HIV and antiretroviral therapy (ART). Within the US-based AMP Up longitudinal cohort study, 608 YAPHIV and 131 YAPHEU completed the NIH Toolbox (NIHT) assessment of cognitive functioning and provided information on mental health, demographic variables, social determinants of health (SDOH), HIV-related health and ARTs. YAPHIV were categorized at entry as YAPHIV-C (history of CDC Class C AIDS-defining criteria or nadir CD4

Cognition · Cognitive skill · Cohort · Cohort study · Health psychology · Longitudinal study · Mental health · Young adult · HIV Research and Treatment · HIV/AIDS Research and Interventions · Maternal Mental Health During Pregnancy and Postpartum