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Impact evaluation of a community-based intervention for prevention of cardiovascular diseases in the slums of Nairobi

The SCALE-UP study

Bibliographic Data

ID19529271
AuthorsSteven van de Vijver (0000-0002-9174-7737, Amsterdam UMC Location University of Amsterdam, corresponding author), Samuel Oti (0000-0003-1035-9511, Amsterdam UMC Location University of Amsterdam), Samuel Oji Oti (African Population and Health Research CenterNairobi), Gabriela B Gomez (0000-0002-7409-798X, University of London), Charles Agyemang (0000-0002-3882-7295, Amsterdam UMC Location University of Amsterdam), Thaddaeus Egondi (African Population and Health Research Center), Eric P Moll Van Charante (0000-0002-1489-5218, Amsterdam UMC Location University of Amsterdam), Eric Moll van Charante, Lizzy M Brewster (0000-0002-7434-0038, Amsterdam UMC Location University of Amsterdam), Catherine Hankins (0000-0002-1642-8592, Amsterdam UMC Location University of Amsterdam), Zlata Tanović (0000-0003-4187-1032, Amsterdam Institute for International Development), Alex Ezeh (0000-0002-1309-4697, African Population and Health Research Center), Catherine Kyobutungi (0000-0002-5344-5631, African Population and Health Research Center), Karien Stronks (0000-0002-0921-2232, Amsterdam UMC Location University of Amsterdam)
Year2016
Volume9
Issue1
Pages30922-30922
Publication date2016-12-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueGlobal Health Action (JOURNAL)
Journal identifiersISSN: 1654-9716 • E-ISSN: 1654-9880
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.3402/gha.v9.30922
PMID27019347
OpenAlexW2303785866
LanguageEN
Citations received6
References cited28

BACKGROUND: A combination of increasing urbanization, behaviour change, and lack of health services in slums put the urban poor specifically at risk of cardiovascular disease (CVD). This study aimed to evaluate the impact of a community-based CVD prevention intervention on blood pressure (BP) and other CVD risk factors in a slum setting in Nairobi, Kenya. DESIGN: Prospective intervention study includes awareness campaigns, household visits for screening, and referral and treatment of people with hypertension. The primary outcome was overall change in mean systolic blood pressure (SBP), while secondary outcomes were changes in awareness of hypertension and other CVD risk factors. We evaluated the intervention's impact through consecutive cross-sectional surveys at baseline and after 18 months, comparing outcomes of intervention and control group, through a difference-in-difference method. RESULTS: We screened 1,531 and 1,233 participants in the intervention and control sites. We observed a significant reduction in mean SBP when comparing before and after measurements in both intervention and control groups, -2.75 mmHg (95% CI -4.33 to -1.18, p=0.001) and -1.67 mmHg (95% CI -3.17 to -0.17, p=0.029), respectively. Among people with hypertension at baseline, SBP was reduced by -14.82 mmHg (95% CI -18.04 to -11.61, p<0.001) in the intervention and -14.05 (95% CI -17.71 to -10.38, p<0.001) at the control site. However, comparing these two groups, we found no difference in changes in mean SBP or hypertension prevalence. CONCLUSIONS: We found significant declines in SBP over time in both intervention and control groups. However, we found no additional effect of a community-based intervention involving awareness campaigns, screening, referral, and treatment. Possible explanations include the beneficial effect of baseline measurements in the control group on behaviour and related BP levels, and the limited success of treatment and suboptimal adherence in the intervention group

Economic growth · Economics · Environmental health · Geography · Community Health and Development · Global Maternal and Child Health · Global Public Health Policies and Epidemiology · Medicine · Nursing · Gerontology

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Unique citing works6
Citations per year0,67
Citation span2017 - 2025 (9)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 5
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