Awareness and management of elevated blood pressure among human immunodeficiency virus–infected adults receiving antiretroviral therapy in urban Zambia

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Bibliographic Data

ID19531170
AuthorsSophie Bauer (University of Bern), Mwanza Wa Mwanza (Centre for Infectious Disease Research in Zambia), Roma Chilengi (0000-0003-0221-9527, Centre for Infectious Disease Research in Zambia), Charles B Holmes (0000-0002-7924-6761, Centre for Infectious Disease Research in Zambia), Zude Zyambo (Centre for Infectious Disease Research in Zambia), Hansjakob Furrer (0000-0002-1375-3146, University of Bern), Matthias Egger (0000-0002-1791-1842, University of Bern), Gilles Wandeler (0000-0002-5278-8763, University of Bern), Michael J Vinikoor (0000-0002-3862-7795, Centre for Infectious Disease Research in Zambia, corresponding author)
Year2017
Volume10
Issue1
Pages1359923-1359923
Publication date2017-01-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueGlobal Health Action (JOURNAL)
Journal identifiersISSN: 1654-9716 • E-ISSN: 1654-9880
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/16549716.2017.1359923
PMID28792285
OpenAlexW2744108305
LanguageEN
Citations received1
References cited21

The prevalence of high blood pressure (HBP) and hypertension (HTN), awareness of the diagnoses, and use of anti-hypertensive drugs were examined among human immunodeficiency virus (HIV)-infected individuals on antiretroviral therapy (ART) in Zambia's capital Lusaka. Within a prospective cohort based at two public sector ART clinics, BP was measured at ART initiation and every 6 months thereafter as a routine clinic procedure. Predictors of HBP (systolic BP ≥140 mmHg or diastolic BP ≥90 mmHg) during one year on ART were analyzed using logistic regression, and the proportion with HTN (2+ episodes of HBP >3 months apart) described. A phone survey was used to understand patient awareness of HBP, use of anti-hypertensive drugs, and history of cardiovascular events (CVE; myocardial infarction or stroke). Among 896 cohort participants, 887 (99.0%) had at least one BP measurement, 98 (10.9%) had HBP, and 57 (6.4%) had HTN. Increasing age (10-year increase in age: adjusted odds ratio [AOR] = 1.50; 95% confidence interval [CI] 1.20-1.93), male sex (AOR = 2.33, 95% CI 1.43-3.80), and overweight/obesity (AOR = 4.07; 95% CI 1.94-8.53) were associated with HBP. Among 66 patients with HBP, 35 (53.0%) reported awareness of the condition, and nine (25.7%) of these reported having had a CVE. Only 14 (21.2%) of those reached reported ever taking an anti-hypertensive drug, and one (1.5%) was currently on treatment. These data suggest that major improvements are needed in the management of HBP among HIV-infected individuals in settings such as Zambia

Blood pressure · Cohort · Confidence interval · Logistic regression · Obesity · Odds ratio · Overweight · Prospective cohort study · Diabetes, Cardiovascular Risks, and Lipoproteins · HIV-related health complications and treatments · HIV/AIDS Research and Interventions · Medicine · Internal Medicine · Pediatrics