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Health systems performance in managing tuberculosis

Analysis of tuberculosis care cascades among high-burden and non-high-burden countries

Bibliographic Data

ID19551448
AuthorsJungyeon Kim (0000-0003-1509-0240, Harvard Global Health Institute), Salmaan Keshavjee (0000-0002-6967-3305, Harvard University), Rifat Atun (0000-0002-1531-5983, Harvard University, corresponding author)
Year2019
Volume9
Issue1
Pages010423-010423
Publication date2019-06-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of Global Health (JOURNAL)
Journal identifiersISSN: 2047-2978 • E-ISSN: 2047-2986
PublisherInternational Society of Global Health (PUBLISHER • GB)
DOI10.7189/jogh.09.010423
PMID31263546
OpenAlexW2924383291
LanguageEN
Citations received4
References cited18

BACKGROUND: Tuberculosis (TB) is a major global health burden, which has been inadequately addressed. This study aims to analyze different patterns and gaps of care along the care cascade across countries and to develop a model to examine the relationship between performance of tuberculosis programmes in high and low burden countries along the tuberculosis care cascade and tuberculosis disease burden. METHODS: We used the World Health Organization's Global TB Database for the year 2016 to construct tuberculosis care cascade consisting of four steps: incidence, diagnosed, treatment started and treatment completed. Based on the constructed care cascades, we analyzed the relationship between health system performance indicators and tuberculosis cascades performance: diagnosed rate, treatment started rate, and treatment completed rate. RESULTS: There are wide differences in access to diagnosis and treatment between high-burden countries and non-high-burden countries. The largest gap was found between incidence and diagnosed rate, with 65% of diagnosed rate for high burden countries and 80% of diagnosed rate for non-high burden countries. We found variations in care performance among high-burden countries. We found a negative relationship between the population health indicators related to the mortality rate and TB care cascade performance. There was a positive relationship between immunization coverage rate and antenatal care indicators and TB care cascade performance. CONCLUSIONS: Well-functioning tuberculosis care cascades and effective health systems are important for the successful management of tuberculosis. While improving screening performance is essential for tuberculosis control especially for high-burden countries, resource should be allocated to improve health system performance, which is weak in high-burden countries. Performance of TB programmes across care cascade could be used as a useful tracer to measure performance of health systems

Burden of disease · Developing country · Disease burden · Economic growth · Environmental health · Health care · Mortality rate · Population · Public health · Tuberculosis · Global Maternal and Child Health · Healthcare Systems and Reforms · Medicine · Nursing · Tuberculosis Research and Epidemiology · Internal Medicine

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Unique citing works4
Citations per year1,33
Citation span2023 - 2025 (3)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 3
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