Perceptions and predictors of Covid-19 vaccine hesitancy among healthcare providers across five countries in sub-Saharan Africa

Datos Bibliográficos

ID19590701
AutoresIsabel Madzorera (0000-0001-7226-5997, Berkeley Public Health Division, autor de correspondencia), Livesy Abokyi (Kintampo Health Research Centre, autor de correspondencia), Livesy Naafoe Abokyi, Edward Anane Apraku (0000-0003-4877-5123, Kintampo Health Research Centre, autor de correspondencia), Edward Apraku, Temesgen Azemraw (Haramaya University, autor de correspondencia), Valentin Boudo (0000-0001-6194-6164, Centre de Recherche en Santé de Nouna, autor de correspondencia), Christabel James (0000-0001-5279-594X, University of Ibadan, autor de correspondencia), Dongqing Wang (0000-0003-3369-5972, Harvard University, autor de correspondencia), Frank Mapendo (0000-0002-0067-7113, Africa Academy for Public Health, autor de correspondencia), Ourohiré Millogo (0000-0002-2552-8122, Centre de Recherche en Santé de Nouna, autor de correspondencia), Nega Assefa (0000-0003-0341-2329, Haramaya University, autor de correspondencia), Angela Chukwu (0000-0001-5596-573X, University of Ibadan, autor de correspondencia), Firehiwot Workneh (0000-0003-1529-987X, Addis Continental Institute of Public Health, autor de correspondencia), Bruno Lankoandé (Université Joseph Ki-Zerbo, autor de correspondencia), Elena C Hemler (0000-0001-6986-9474, Harvard University, autor de correspondencia), Abbas Ismail (0000-0002-6720-7212, The University of Dodoma, autor de correspondencia), Sulemana Watara Abubakari (0000-0002-3448-9938, Kintampo Health Research Centre, autor de correspondencia), Kwaku Poku Asante (0000-0001-9158-351X, Kintampo Health Research Centre, autor de correspondencia), Yemane Berhane (0000-0002-2527-1339, Addis Continental Institute of Public Health, autor de correspondencia), Japhet Killewo (0000-0001-6998-6750, Africa Academy for Public Health, autor de correspondencia), Ayoade Oduola (0000-0001-6891-785X, University of Ibadan, autor de correspondencia), Ali Sié (0000-0002-3959-2520, Centre de Recherche en Santé de Nouna, autor de correspondencia), Abdramane Soura (0000-0002-1539-6357, Université Joseph Ki-Zerbo, autor de correspondencia), Mary Mwanyika‐Sando (0000-0002-8079-5960, Africa Academy for Public Health, autor de correspondencia), Mary Mwanyika-Sando, Said Vuai (0000-0003-0187-1206, The University of Dodoma, autor de correspondencia), E R Smith (0000-0002-1745-5728, Milken Institute, autor de correspondencia), Emily Smith (0000-0002-2633-5189), Till Baernighausen (Heidelberg University, autor de correspondencia), Tajudeen Raji (0000-0001-9849-5088, Africa Centres for Disease Control and Prevention, autor de correspondencia), Wafaie W Fawzi (0000-0002-2908-600X, Harvard University, autor de correspondencia)
EditoresEverton Falcão De Oliveira (0000-0002-0074-5278)
Año2025
Volumen5
Número2
Páginase0003956
Fecha de publicación2025-02-21
Peer ReviewedSí
Open AccessSí
TipoARTICLE
RevistaPLOS Global Public Health (JOURNAL)
Identificadores de la revistaISSN: 2767-3375 • E-ISSN: 2767-3375
EditorialPublic Library of Science (PLoS) (PUBLISHER)
DOI10.1371/journal.pgph.0003956
PMID39982973
OpenAlexW4407851838
IdiomaEN
Citas recibidas1
Referencias citadas25

The African continent has some of the world’s lowest COVID-19 vaccination rates. While the limited availability of vaccines is a contributing factor, COVID-19 vaccine hesitancy among healthcare providers (HCP) is another factor that could adversely affect efforts to control infections on the continent. We sought to understand the extent of COVID-19 vaccine hesitancy among HCP, and its contributing factors in Africa. We evaluated COVID-19 vaccine hesitancy among 1,499 HCP enrolled in a cross-sectional study conducted as a telephone survey in Burkina Faso, Ethiopia, Nigeria, Tanzania, and Ghana between July to December of 2021. We defined COVID-19 vaccine hesitancy among HCP as self-reported responses of definitely not, maybe, unsure, or undecided on whether to get the COVID-19 vaccine, compared to definitely getting the vaccine. We used log-binomial or modified Poisson regression models to evaluate factors influencing vaccine hesitancy among HCP. Approximately 65.6% of the HCP interviewed were nurses and the mean age (±SD) of participants was 35.8 (±9.7) years. At least 67% of the HCP reported being vaccinated. COVID-19 vaccine hesitancy affected 45.7% of the HCP in Burkina Faso, 25.7% in Tanzania, 9.8% in Ethiopia, 9% in Ghana and 8.1% in Nigeria. Among unvaccinated HCP reasons for low vaccine uptake included concern about vaccine effectiveness, side effects, and fear of receiving experimental and unsafe vaccines. HCP reporting that COVID-19 vaccines are very effective (RR: 0.21, 95% CI: 0.08, 0.55), and older HCP (45 or older vs.20–29 years, RR: 0.65, 95% CI: 0.44, 0.95) were less likely to be vaccine-hesitant. Nurses were more likely to be vaccine-hesitant (RR 1.38, 95% CI: 1.01, 1.89) than doctors. Information asymmetry among HCP, beliefs about vaccine effectiveness, and the endorsement of vaccines by public health institutions may be important. Efforts to address hesitancy should consider information and knowledge gaps among different cadres of HCP alongside efforts to increase vaccine supply

Cross-sectional study · Disease · Environmental health · Family medicine · Geography · Health care · Poisson regression · Population · Tanzania · Vaccination · COVID-19 epidemiological studies · Demography · Medicine · SARS-CoV-2 and COVID-19 Research · Vaccine Coverage and Hesitancy · Internal Medicine · Virology