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An emerging Timer-2C framework for addressing barriers to research culture and productivity among local healthcare providers in the Middle East and sub-Saharan Africa

A qualitative study and modified Delphi approach

Bibliographic Data

ID19595040
AuthorsBeryne Odeny (0000-0002-4429-2274, Washington University in St. Louis, corresponding author), Dorothy I Mangale (0000-0003-1264-405X, Washington University in St. Louis), Dorothy Mangale, Dhananjaya Sharma (0000-0002-0604-8676, Netaji Subhash Chandra Bose Medical College), Mariam Balogun (Washington University in St. Louis), Elizabeth A Bukusi (0000-0002-2031-2808, Kenya Medical Research Institute), Elizabeth Bukusi, Fátima Suleman (0000-0002-5963-2892, University of KwaZulu-Natal), Miliard Derbew (0000-0003-0208-9742, Addis Ababa University), Juliet Iwelunmor (0000-0003-1376-5443, Washington University in St. Louis), Ermyas Birru (0000-0001-9393-2533, University of Washington), Isaac Che Ngang (0000-0002-5691-6961, Washington University in St. Louis), Akila Anandarajah (0000-0002-0430-9561, Washington University in St. Louis), Vaishnavi Mamillapalle (0009-0007-4040-7031, Washington University in St. Louis), Wael Almahmeed (0000-0003-0312-9910, Cleveland Clinic)
EditorsGraeme Hoddinott (0000-0001-5915-8126)
Year2026
Volume6
Issue4
Pagese0006046
Publication date2026-04-08
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenuePLOS Global Public Health (JOURNAL)
Journal identifiersISSN: 2767-3375 • E-ISSN: 2767-3375
PublisherPublic Library of Science (PLoS) (PUBLISHER)
DOI10.1371/journal.pgph.0006046
PMID41950187
OpenAlexW4411523654
LanguageEN
References cited25

Contributions from healthcare professionals in the Middle East and North Africa (MENA) and sub-Saharan Africa (SSA) to global health research remain disproportionately low. We conceptualized the TIMER-2C framework to capture the multi-level barriers and facilitators shaping research productivity among local healthcare professionals in MENA and SSA. We conducted qualitative interviews using a modified Delphi approach comprising two rounds to: 1) identify barriers and facilitators, and 2) establish consensus on the most prominent factors influencing research productivity. We purposively sampled 17 participants from Jordan, Qatar, Egypt, Lebanon, North Sudan, South Sudan, Nigeria, Ghana, Kenya, Uganda, Ethiopia, South Africa and India. Interview guides were grounded in theoretical frameworks. Transcripts were analyzed for barriers, facilitators, and recommendations for increasing research output. Barriers and facilitators to research productivity occurred at individual, institutional, national, and global levels. Key barriers included limited time, funding, mentorship, and research training; institutional prioritization of clinical and teaching duties over research; lack of national investment and supportive policies; and global challenges in funding, publishing, and collaboration. Facilitators included personal motivation, protected time, access to training and mentorship, institutional support for research, national funding strategies, and meaningful global partnerships that value local contributions. We identified six themes and one overarching theme from which we coined the TIMER-2C framework: 1) T ime, 2) I nstability, Interest & Infrastructure, 3) M oney & Resources, 4) E xpertise & Experience, 5) R ecognition, and 6) constructive C ollaboration, together fostering a positive research C ulture (2C). Research culture emerged as an overarching influence on research contributions. We unveil an emerging framework, the TIMER-2C , that depicts relationships among multilevel factors shaping research productivity and offers a useful tool to guide and evaluate local capacity-building strategies. We recommend further application of this framework to guide the design, implementation and evaluation of multi-pronged strategies to enhance research contributions from MENA, SSA, and similar contexts

Economic growth · Health care · Implementation research · Medical education · Mentorship · Political science · Productivity · Psychological intervention · Public relations · Qualitative research · Social science · Sociology · Advances in Oncology and Radiotherapy · Global Health and Surgery · Global Health Workforce Issues · Medicine · Nursing

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