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How Dissemination and Implementation Science Can Contribute to the Advancement of Learning Health Systems

Bibliographic Data

ID21614337
AuthorsKaty E Trinkley (0000-0003-2041-7404, K.E. Trinkleyis associate professor, Departments of Clinical Pharmacy and Medicine and Adult and Child Consortium for Outcomes Research and Delivery Science (ACCORDS), University of Colorado Anschutz Medical Center, and clinical informaticist, Department of Clinical Informatics, UCHealth, Aurora, Colorado; ORCID:., corresponding author), P Michael Ho (0000-0002-7775-6266, P.M. Hois professor, Department of Medicine, University of Colorado Anschutz Medical Campus, and professor, VA Eastern Colorado Health Care System, Aurora, Colorado; ORCID:.), Russell E Glasgow (0000-0003-4218-3231, R.E. Glasgowis research professor, Department of Family Medicine, and director, Dissemination and Implementation Science Program, ACCORDS, University of Colorado Anschutz Medical Center, Aurora, Colorado; ORCID:.), Amy G Huebschmann (0000-0002-9329-3142, A.G. Huebschmannis associate professor, Division of General Internal Medicine, ACCORDS and Ludeman Family Center for Women’s Health Research, University of Colorado Anschutz Medical Center, Aurora, Colorado; ORCID:.)
Year2022
Volume97
Issue10
Pages1447-1458
Publication date2022-10-01
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueAcademic Medicine (JOURNAL)
Journal identifiersISSN: 1040-2446 • E-ISSN: 1938-808X
PublisherOxford University Press (OUP) (PUBLISHER)
DOI10.1097/acm.0000000000004801
PMID35796045
OpenAlexW4284886444
LanguageEN
Citations received6
References cited78

Many health systems are working to become learning health systems (LHSs), which aim to improve the value of health care by rapidly, continuously generating evidence to apply to practice. However, challenges remain to advance toward the aspirational goal of becoming a fully mature LHS. While some important challenges have been well described (i.e., building system-level supporting infrastructure and the accessibility of inclusive, integrated, and actionable data), other key challenges are underrecognized, including balancing evaluation rapidity with rigor, applying principles of health equity and classic ethics, focusing on external validity and reproducibility (generalizability), and designing for sustainability. Many LHSs focus on continuous learning cycles, but with limited consideration of issues related to the rapidity of these learning cycles, as well as the sustainability or generalizability of solutions. Some types of data have been consistently underrepresented, including patient-reported outcomes and preferences, social determinants, and behavioral and environmental data, the absence of which can exacerbate health disparities. A promising approach to addressing many challenges that LHSs face may be found in dissemination and implementation (D&I) science. With an emphasis on multilevel dynamic contextual factors, representation of implementation partner engagement, pragmatic research, sustainability, and generalizability, D&I science methods can assist in overcoming many of the challenges facing LHSs. In this article, the authors describe the current state of LHSs and challenges to becoming a mature LHS, propose solutions to current challenges, focusing on the contributions of D&I science with other methods, and propose key components and characteristics of a mature LHS model that others can use to plan and develop their LHSs

Data science · Generalizability theory · Health care · Knowledge management · Management science · Political science · Sustainability · Computer Science · Engineering · Health Policy Implementation Science · Health Systems, Economic Evaluations, Quality of Life · Interprofessional Education and Collaboration · Psychology

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    Junyi Wang•Journal of Education for Teaching…•2026

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  • Making Implementation Science More Rapid

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Unique citing works6
Citations per year1,5
Citation span2022 - 2026 (5)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 6
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