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Reducing surgical site infections and mortality among obstetric surgical patients in Tanzania

A pre-evaluation and postevaluation of a multicomponent safe surgery intervention

Bibliographic Data

ID21878728
AuthorsEdwin Charles Ernest (JHPIEGO, Dar es Salaam, Tanzania, United Republic of), Edwin Ernest (0000-0002-6990-3051, corresponding author), Augustino Hellar (0000-0002-5095-1483, JHPIEGO, Dar es Salaam, Tanzania, United Republic of), John Varallo (0000-0002-4745-5489, JHPIEGO, Baltimore, Maryland, USA), Leopold Tibyehabwa (JHPIEGO, Dar es Salaam, Tanzania, United Republic of), Margaret Mary Bertram (JHPIEGO, Baltimore, Maryland, USA), Laura Fitzgerald (JHPIEGO, Baltimore, Maryland, USA), Adam Katoto (JHPIEGO, Dar es Salaam, Tanzania, United Republic of), Stella Mshana (JHPIEGO, Dar es Salaam, Tanzania, United Republic of), Dorcas Simba (JHPIEGO, Dar es Salaam, Tanzania, United Republic of), Kelvin Gwitaba (JHPIEGO, Dar es Salaam, Tanzania, United Republic of), Rohini Boddu (Johns Hopkins University), Shehnaz Alidina (0000-0002-4403-7871, Harvard University), Geofrey Giiti (0000-0001-8719-6437, Catholic University of Health and Allied Sciences), Albert Kihunrwa (0000-0003-3495-6257, Bugando Medical Centre), Belinda Balandya (0000-0002-5592-3369, Muhimbili University of Health and Allied Sciences), David Urassa (0000-0002-0970-0826, Muhimbili University of Health and Allied Sciences), Yahya Hussein (Ministry of Education and Vocation Training), Caroline Damien (Ministry of Health, Community Development, Gender, Elderly and Children), Brendan Wackenreuter (JHPIEGO, Baltimore, Maryland, USA), David Barash (Developing Health Globally, GE Foundation, Fairfield, Connecticut, USA), Melissa Morrison (The ELMA Philanthropies Services (U.S.), New York, New York, USA), Cheri Reynolds (Assist International, Ripon, New York, USA), Alice Christensen (0000-0001-6731-4045, JHPIEGO, Dar es Salaam, Tanzania, United Republic of), Ahmed Makuwani (Ministry of Health, Community Development, Gender, Elderly and Children)
Year2021
Volume6
Issue12
Pagese006788
Publication date2021-12-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueBMJ Global Health (JOURNAL)
Journal identifiersISSN: 2059-7908 • E-ISSN: 2059-7908
PublisherBMJ (PUBLISHER • GB)
DOI10.1136/bmjgh-2021-006788
PMID34876458
OpenAlexW4200354985
LanguageEN
References cited35

INTRODUCTION: Despite ongoing maternal health interventions, maternal deaths in Tanzania remain high. One of the main causes of maternal mortality includes postoperative infections. Surgical site infection (SSI) rates are higher in low/middle-income countries (LMICs), such as Tanzania, compared with high-income countries. We evaluated the impact of a multicomponent safe surgery intervention in Tanzania, hypothesising it would (1) increase adherence to safety practices, such as the WHO Surgical Safety Checklist (SSC), (2) reduce SSI rates following caesarean section (CS) and (3) reduce CS-related perioperative mortality rates (POMRs). METHODS: We conducted a pre-cross-sectional/post-cross-sectional study design to evaluate WHO SSC utilisation, SSI rates and CS-related POMR before and 18 months after implementation. Our interventions included training of inter-professional surgical teams, promoting use of the WHO SSC and introducing an infection prevention (IP) bundle for all CS patients. We assessed use of WHO SSC and SSI rates through random sampling of 279 individual CS patient files. We reviewed registers and ward round reports to obtain the number of CS performed and CS-related deaths. We compared proportions of individuals with a characteristic of interest during pre-implementation and post implementation using the two-proportion z-test at p≤0.05 using STATA V.15. RESULTS: The SSC utilisation rate for CS increased from 3.7% (5 out of 136) to 95.1% (136 out of 143) with p<0.001. Likewise, the proportion of women with SSI after CS reduced from 14% during baseline to 1% (p=0.002). The change in SSI rate after the implementation of the safe surgery interventions is statistically significant (p<0.001). The CS-related POMR decreased by 38.5% (p=0.6) after the implementation of safe surgery interventions. CONCLUSION: Our findings show that our intervention led to improved utilisation of the WHO SSC, reduced SSIs and a drop in CS-related POMR. We recommend replication of the interventions in other LMICs

Caesarean section · Checklist · Cross-sectional study · Environmental health · Mortality rate · Perioperative · Pregnancy · Psychological intervention · Public health · Surgical site infection · Tanzania · Global Health and Surgery · Maternal and Perinatal Health Interventions · Medicine · Nursing · Surgical site infection prevention · Emergency Medicine · Surgery

  • Global Surgery 2030

    Open Access•John G Meara, Andrew J M Leather et al.•The Lancet•2015

  • A Surgical Safety Checklist to Reduce Morbidity and Mortality in a Global Population

    Alex B Haynes, Thomas G Weiser et al.•New England Journal of Medicine•2009

  • Teamwork in healthcare

    Michael A Rosen, Deborah DiazGranados et al.•American Psychologist•2018

Citation velocityhistorical
Highly citedNo
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