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How conflicts of interest hinder effective regulation of healthcare

An analysis of antimicrobial use regulation in Cambodia, Indonesia and Pakistan

Bibliographic Data

ID21880163
AuthorsMishal Khan (0000-0002-8967-1761, Aga Khan University, corresponding author), Afifah Rahman-Shepherd (0000-0002-8845-9275, London School of Hygiene & Tropical Medicine), Sothavireak Bory (University of Health Science), Sophea Chhorn (University of Health Science), Anna Durrance-Bagale (0000-0001-6674-1862, London School of Hygiene & Tropical Medicine), Rumina Hasan (0000-0003-3738-117X, Aga Khan University), Sotheara Heng (University of Health Science), Socheata Phou (0000-0003-1923-6147, University of Health Science), Chanra Prien (University of Health Science), Ari Probandari (0000-0003-3171-5271, Sebelas Maret University), Vonthanak Saphonn (0000-0002-5620-0517, University of Health Science), Sovanthida Suy (University of Health Science), Virginia Wiseman (0000-0002-7911-0741, UNSW Sydney), Luh Putu Lila Wulandari (0000-0002-3397-3648, Udayana University), Johanna Hanefeld (0000-0001-9487-2333, Robert Koch Institute)
Year2022
Volume7
Issue5
Pagese008596
Publication date2022-05-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueBMJ Global Health (JOURNAL)
Journal identifiersISSN: 2059-7908 • E-ISSN: 2059-7908
PublisherBMJ (PUBLISHER • GB)
DOI10.1136/bmjgh-2022-008596
PMID35589155
OpenAlexW4280498252
LanguageEN
Citations received5
References cited41

BACKGROUND: There has been insufficient attention to a fundamental force shaping healthcare policies-conflicts of interest (COI). We investigated COI, which results in the professional judgement of a policymaker or healthcare provider being compromised by a secondary interest, in relation to antimicrobial use, thereby illuminating challenges to the regulation of medicines use more broadly. Our objectives were to characterise connections between three groups-policymakers, healthcare providers and pharmaceutical companies-that can create COI, and elucidate the impacts of COI on stages of the policy process. METHODS: Using an interpretive approach, we systematically analysed qualitative data from 136 in-depth interviews and five focus group discussions in three Asian countries with dominant private healthcare sectors: Cambodia, Indonesia and Pakistan. FINDINGS: We characterised four types of connections that were pervasive between the three groups: financial, political, social and familial. These connections created strong COI that could impact all stages of the policy process by: preventing issues related to medicines sales from featuring prominently on the agenda; influencing policy formulation towards softer regulatory measures; determining resource availability for, and opposition to, policy implementation; and shaping how accurately the success of contested policies is reported. INTERPRETATION: Our multicountry study fills a gap in empirical evidence on how COI can impede effective policies to improve the quality of healthcare. It shows that COI can be pervasive, rather than sporadic, in influencing regulation of medicine use, and highlights that, in addition to financial connections, other types of connections should be examined as important drivers of COI

Antimicrobial · Biology · Development economics · Economic growth · Economics · Health care · Healthcare system · Political science · Antibiotic Use and Resistance · Medicine · Pharmaceutical Economics and Policy · Pharmaceutical industry and healthcare · Microbiology

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Unique citing works5
Citations per year1,67
Citation span2023 - 2024 (2)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 5
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