Global, Regional, and National Death, and Disability-Adjusted Life-Years (Dalys) for Cardiovascular Disease in 2017 and Trends and Risk Analysis From 1990 to 2017 Using the Global Burden of Disease Study and Implications for Prevention

Bibliographic Data

ID22073084
AuthorsZhiyong Li (0000-0003-3237-4317, Chinese Academy of Medical Sciences & Peking Union Medical College), Longfei Lin (0000-0001-6690-1600, Chinese Academy of Medical Sciences & Peking Union Medical College), Hongwei Wu (0000-0002-3768-4608, Chinese Academy of Medical Sciences & Peking Union Medical College), Lei Yan (0000-0001-8408-5475, Community Health Center), Huanhuan Wang (0000-0002-8886-8589, Chinese Academy of Medical Sciences & Peking Union Medical College), Hongjun Yang (0000-0001-6596-4212, Chinese Academy of Medical Sciences & Peking Union Medical College, corresponding author), Hui Li (0000-0001-9355-1116, Chinese Academy of Medical Sciences & Peking Union Medical College, corresponding author)
Year2021
Volume9
Pages559751-559751
Publication date2021-10-29
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueFrontiers in Public Health (JOURNAL)
Journal identifiersISSN: 2296-2565 • E-ISSN: 2296-2565
PublisherFrontiers Media SA (PUBLISHER • CH)
DOI10.3389/fpubh.2021.559751
PMID34778156
OpenAlexW3210120351
LanguageEN
Citations received3
References cited38

Background: Cardiovascular disease is the leading cause of death worldwide and a major barrier to sustainable human development. The objective of this study was to evaluate the global, sex, age, region, and country-related cardiovascular disease (CVD) burden, as well as the trends, risk factors, and implications for the prevention of CVD. Methods: Detailed information from 1990 to 2017, including global, regional, and national rates of CVD, and 11 categories of mortality and disability-adjusted life years (DALYs) were collected from the Global Burden of Disease Study 2017. The time-dependent change in the trends of CVD burdens was evaluated by annual percentage change. Results: More than 17 million people died from CVD in 2017, which was approximately two times as many as cancer, and increased nearly 50% compared with 1990. Ischemic heart disease and stroke accounted for 85% of the total age-standardized death rate (ASDR) of CVD. The ASDR and age-standardized DALYs rate (ASYR) of CVD were 1.5 times greater in men compared with women. People over the age of 50 were especially at risk for developing CVD, with the number of cases and deaths in this age group accounting for more than 90% of all age groups. CVD mortality was related to regional economic development and the social demographic index. In regions with a high economic income or socio-demographic index, there was a greater decline in the ASDR of CVD. The ASDR of CVD in high SDI regions decreased more than 50% from 1990 to 2017. Tobacco use, diets low in whole grains, diets high in sodium, and high systolic blood pressure were the important risk factors related to CVD mortality. Conclusions: CVD remains a major cause of death and chronic disability in all regions of the world. Ischemic heart disease and stroke account for the majority of deaths related to CVD. Although the mortality rate for CVD has declined in recent years from a global perspective, the results of CVD data in 2017 suggest that the mortality and DALYs of CVD varied in different ages, sexes, and countries/regions around the world. Therefore, it is necessary to elucidate the specific characteristics of global CVD burden and establish more effective and targeted prevention strategies

Burden of disease · Cause of death · Disease · Disease burden · Environmental health · Global health · Life expectancy · Mortality rate · Population · Public health · Years of potential life lost · Cardiovascular Health and Risk Factors · Demography · Global Public Health Policies and Epidemiology · Healthcare Systems and Public Health · Medicine · Gerontology · Internal Medicine · Surgery