Factors associated with caregiver compliance to an HIV disclosure intervention and its effect on HIV and mental health outcomes among children living with HIV
Post-hoc instrumental variable-based analysis of a cluster randomized trial in Eldoret, Kenya
Bibliographic Data
| ID | 22078568 |
|---|---|
| Authors | Elizabeth B Magill, Elizabeth Magill (0000-0001-8398-1200, Mount Sinai Health System, corresponding author), Winstone Nyandiko (0000-0002-7639-9287, Moi University), Aaron Baum (0000-0003-4999-3480, Mount Sinai Health System), Josephine Aluoch (0000-0003-2174-2006, AMPATH), Ashley Chory (0000-0002-3551-5341, Mount Sinai Health System), Celestine Ashimoshi (AMPATH), Janet Lidweye (AMPATH), Tabitha Njoroge (AMPATH), Festus Sang (0000-0003-0284-9131, AMPATH), Jack Nyagaya (AMPATH), MICHAEL SCANLON (0000-0002-0334-5640, Center for Global Health), Joseph W Hogan (0000-0001-7959-7361, Brown University), Joseph Hogan, Rachel Vreeman (0000-0001-5460-8204, Mount Sinai Health System, corresponding author) |
| Year | 2023 |
| Volume | 11 |
| Pages | 1150744-1150744 |
| Publication date | 2023-05-05 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | Frontiers in Public Health (JOURNAL) |
| Journal identifiers | ISSN: 2296-2565 • E-ISSN: 2296-2565 |
| Publisher | Frontiers Media SA (PUBLISHER • CH) |
| DOI | 10.3389/fpubh.2023.1150744 |
| PMID | 37213654 |
| OpenAlex | W4377221050 |
| Language | EN |
| Citations received | 2 |
| References cited | 54 |
Background: The HADITHI study is a cluster-randomized trial of children living with HIV and their caregivers in Kenya that aimed to increase rates of caregiver disclosure of their child's HIV status, encourage earlier status disclosure, and improve pediatric mental health and HIV outcomes. This analysis identified characteristics predicting caregiver non-responsiveness and compared outcomes among children based on disclosure status. Methods: A penalized logistic regression model with lasso regularization identified the most important predictors of disclosure. The two-stage least squares instrumental variable approach was used to assess outcomes accounting for non-compliance to disclosure. Results: Caregiver non-isolation and shorter time on antiretroviral therapy were predictive of HIV status disclosure. There were no statistically significant differences found in CD4 percentage, depression status, or mental and emotional status based on disclosure status up to 24 months-post intervention. Conclusion: These findings have implications for specialists seeking to tailor disclosure interventions to improve caregiver-child dyad responsiveness
Developmental psychology · Dyad · Logistic regression · Mental health · Psychiatry · Psychological intervention · Adolescent Sexual and Reproductive Health · Clinical Psychology · Health Education and Validation · HIV/AIDS Research and Interventions · Medicine · Psychology · Internal Medicine
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Disclosure of HIV status to children in resource‐limited settings
We never thought this would happen
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Extent of disclosure
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Factors Leading to Self-Disclosure of a Positive HIV Diagnosis in Nairobi, Kenya
What will my child think of me if he hears I gave him HIV?”
Sankofa pediatric HIV disclosure intervention did not worsen depression scores in children living with HIV and their caregivers in Ghana
Disclosure of HIV Status and Adherence to Daily Drug Regimens Among HIV-infected Children in Uganda
| Unique citing works | 2 |
|---|---|
| Citations per year | 2 |
| Citation span | 2025 - 2026 (2) |
| Citation velocity | current |
| Highly cited | No |
| Citation types | Neutral: 2 |