Phylogeography of mitochondrial DNA in western Europe

Bibliographic Data

ID23328161
AuthorsMartin B Richards (0000-0003-3118-0967, John Radcliffe Hospital, corresponding author), Vincent Macaulay (0000-0001-9084-2700, John Radcliffe Hospital), V A MACAULAY, H-J BANDELT, Bryan Sykes (John Radcliffe Hospital), B C SYKES
Year1998
Volume62
Issue3
Pages241-260
Publication date1998-05-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAnnals of Human Genetics (JOURNAL)
Journal identifiersISSN: 0003-4800 • E-ISSN: 1469-1809
PublisherWiley (PUBLISHER • GB)
DOI10.1046/j.1469-1809.1998.6230241.x
PMID9803269
OpenAlexW1974472861
LanguageEN
Citations received97
References cited10

For most of the past century, prehistorians have had to rely on the fossil and archaeological records in order to reconstruct the past. In the last few decades, this evidence has been substantially supplemented from classical human genetics. More recently, phylogenetic analyses of DNA sequences that incorporate geographical information have provided a high‐resolution tool for the investigation of prehistoric demographic events, such as founder effects and population expansions. These events can be dated using a molecular clock when the mutation rate and founder haplotypes are known. We have previously applied such methods to sequence data from the mitochondrial DNA control region, to suggest that most extant mitochondrial sequences in western Europe have a local ancestry in the Early Upper Palaeolithic, with a smaller proportion arriving from the Near East in the Neolithic. Here, we describe a cladistic notation for mitochondrial variation and expand upon our earlier analysis to present a more detailed portrait of the European mitochondrial record.

Ancient DNA · Biology · Evolutionary biology · Gene · Genealogy · Genotype · Geography · Haplogroup · Haplotype · Mitochondrial DNA · Molecular clock · mtDNA control region · Phylogenetic tree · Phylogeography · Population · Prehistory · Sequence (biology) · Demography · Forensic and Genetic Research · Genetic diversity and population structure · Genetics · Genomics and Phylogenetic Studies · History · Paleontology