Understanding the mental health of youth living with perinatal HIV infection

Lessons learned and current challenges

Bibliographic Data

ID23357583
AuthorsClaude Ann Mellins (0000-0002-1978-7638, New York Psychoanalytic Society and Institute, corresponding author), Kathleen Malee (0000-0002-6384-1283, Northwestern University), Kathleen M Malee
Year2013
Volume16
Issue1
Pages18593-18593
Publication date2013-01-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueJournal of the International AIDS Society (JOURNAL)
Journal identifiersISSN: 1758-2652 • E-ISSN: 1758-2652
PublisherWiley (PUBLISHER • GB)
DOI10.7448/ias.16.1.18593
PMID23782478
OpenAlexW2015884554
LanguageEN
Citations received100
References cited92

INTRODUCTION: Across the globe, children born with perinatal HIV infection (PHIV) are reaching adolescence and young adulthood in large numbers. The majority of research has focused on biomedical outcomes yet there is increasing awareness that long-term survivors with PHIV are at high risk for mental health problems, given genetic, biomedical, familial and environmental risk. This article presents a review of the literature on the mental health functioning of perinatally HIV-infected (PHIV+) adolescents, corresponding risk and protective factors, treatment modalities and critical needs for future interventions and research. METHODS: An extensive review of online databases was conducted. Articles including: (1) PHIV+ youth; (2) age 10 and older; (3) mental health outcomes; and (4) mental health treatment were reviewed. Of 93 articles identified, 38 met inclusion criteria, the vast majority from the United States and Europe. RESULTS: These studies suggest that PHIV+ youth experience emotional and behavioural problems, including psychiatric disorders, at higher than expected rates, often exceeding those of the general population and other high-risk groups. Yet, the specific role of HIV per se remains unclear, as uninfected youth with HIV exposure or those living in HIV-affected households displayed similar prevalence rates in some studies, higher rates in others and lower rates in still others. Although studies are limited with mixed findings, this review indicates that child-health status, cognitive function, parental health and mental health, stressful life events and neighbourhood disorder have been associated with worse mental health outcomes, while parent-child involvement and communication, and peer, parent and teacher social support have been associated with better function. Few evidence-based interventions exist; CHAMP+, a mental health programme for PHIV+ youth, shows promise across cultures. CONCLUSIONS: This review highlights research limitations that preclude both conclusions and full understanding of aetiology. Conversely, these limitations present opportunities for future research. Many PHIV+ youth experience adequate mental health despite vulnerabilities. However, the focus of research to date highlights the identification of risks rather than positive attributes, which could inform preventive interventions. Development and evaluation of mental health interventions and preventions are urgently needed to optimize mental health, particularly for PHIV+ youth growing up in low-and-middle income countries.

Environmental health · Mental health · Population · Psychiatry · Psychological intervention · Clinical Psychology · HIV Research and Treatment · HIV/AIDS Research and Interventions · Maternal Mental Health During Pregnancy and Postpartum · Medicine · Gerontology