Methodological aspects of the micronutrient assessment in the Brazilian National Survey on Child Nutrition (Enani-2019)

A Population-Based Household Survey

Bibliographic Data

ID5167366
AuthorsInês Rugani Ribeiro De Castro (0000-0002-7479-4400, Universidade do Estado do Rio de Janeiro), Paula Normando (0000-0002-6443-7733, Universidade Federal do Rio de Janeiro), Pedro Gomes Andrade (0000-0002-0098-6047, Universidade Federal do Rio de Janeiro), Flávia Fioruci Bezerra (0000-0002-6594-4323, Universidade do Estado do Rio de Janeiro), Marta Citelli (0000-0003-1380-3729, Universidade do Estado do Rio de Janeiro), Lucia Fatima Campos Pedrosa (0000-0002-5436-5115, Universidade Federal do Rio Grande do Norte), Alceu Afonso Jordão Junior (0000-0003-1288-0802, Universidade de São Paulo), Alceu Afonso Jordão (Universidade de Ribeirão Preto), Pedro I C Lira (0000-0002-1534-1620, Universidade Federal de Pernambuco), Fábio Augusto Kurscheidt (0000-0002-0863-7765, Diagnósticos do Brasil, Brasil), Paulo Ricardo Portella Da Silva (0000-0002-1002-9136, Diagnósticos do Brasil, Brasil), Keronlainy Salvatte (0000-0002-1314-9862, Universidade Federal do Rio de Janeiro), Elisa Maria De Aquino Lacerda (0000-0002-1830-4278, Universidade do Estado do Rio de Janeiro), Luiz Antonio Dos Anjos (0000-0002-5257-6912, Universidade Federal Fluminense), Cristiano Siqueira Boccolini (0000-0002-4804-5641, Fundação Oswaldo Cruz), Gilberto Kac (0000-0001-8603-9077, Universidade Federal do Rio de Janeiro)
Year2021
Volume37
Issue8
Pagese00301120-e00301120
Publication date2021-01-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueCadernos de Saude Publica (JOURNAL)
Journal identifiersISSN: 0102-311X • E-ISSN: 1678-4464
PublisherFapUNIFESP (SciELO) (PUBLISHER)
DOI10.1590/0102-311x00301120
PMID34495100
OpenAlexW3196464163
SCIELO_PIDS0102-311X2021000800505
LanguageEN
Citations received8
References cited19

This article aims to present methodological aspects on the collection, analyses, coverage, challenges, and the lessons learned from laboratory assessment of micronutrients on the Brazilian National Survey on Child Nutrition (ENANI-2019). This is a household survey on a probability sample of children under five years of age from 123 Brazilian municipalities in all 26 states and the Federal District. Blood samples were drawn by venipuncture at the homes of children 6 to 59 months of age. This procedure was performed by experienced phlebotomists from the laboratories located in the selected municipalities and scheduled in advance. Blood and serum levels were measured for biomarkers of nutritional status, using the services of a clinical test laboratory with nationwide coverage, for the following micronutrients: iron (hemoglobin and ferritin), zinc, selenium, folic acid, and vitamins A, B1, B6, B12, D, and E. C-reactive protein was analyzed as a marker of inflammation. A barcode identifier was used to track the blood samples and to link the biochemical test results to the other data collected in the survey. A total of 14,558 children were studied. Of the 12,598 eligible children, 8,829 (70.1%) had blood samples drawn. Of the total number of children who had samples drawn, 91.8% (n = 8,025) have results for at least nine of the 12 analyses performed. Coverage of the analysis varied from 95% (for vitamins A and E) to 84.2% (for folic acid). Aliquots of whole blood and serum were stored in a biorepository for future analyses. The results of this pioneering study in the country will back the formulation and, when necessary, the reorientation of public policies in food and nutrition

Environmental health · Micronutrient · National Health and Nutrition Examination Survey · Pathology · Population · Venipuncture · Child Nutrition and Water Access · Heavy Metal Exposure and Toxicity · Iron Metabolism and Disorders · Medicine · Surgery