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Socioeconomic Position and Inflammatory and Immune Biomarkers of Cardiovascular Disease

Applications to the Panel Study of Income Dynamics

Bibliographic Data

ID5958444
AuthorsA E Aiello (0000-0001-7029-2537, University of Michigan, corresponding author), George A Kaplan (University of Michigan)
Year2009
Volume55
Issue2
Pages178-205
Publication date2009-12-03
Peer ReviewedYes
Open AccessNo
TypeARTICLE
VenueBiodemography and Social Biology (JOURNAL)
Journal identifiersISSN: 1948-5565 • E-ISSN: 1948-5573
PublisherInforma UK Limited (PUBLISHER • GB)
DOI10.1080/19485560903382304
PMID20183904
PMCIDPMC3319671
OpenAlexW2047302620
LanguageEN
Citations received12
References cited190

Biomarkers are an important aspect of research linking psychosocial stress and health. This article aims to characterize the biological pathways that may mediate the relationship between socioeconomic position (SEP) and cardiovascular disease (CVD) and address opportunities for further research within the Panel Study of Income Dynamics (PSID), with a focus on psychosocial stressors related to SEP. We review the literature on CVD biomarkers, including adhesion and proinflammatory molecules (interleukin-6, other cytokines, C-reactive proteins, fibrinogen, etc.) and microbial pathogens. The impact of socioeconomic determinants and related psychosocial stressors on CVD biomarkers mediated by behavioral and central nervous system pathways are described. We also address measurement and feasibility issues, including specimen collection methods, processing and storage procedures, laboratory error, and within-person variability. In conclusion, we suggest that PSID consider adding important assessments of specific CVD biomarkers and mediating behavioral measures, health, and medications that will ultimately address many of the gaps in the literature regarding the relationship between SEP and cardiovascular health

Disease · Environmental health · Inflammation · Pathology · Population · Proinflammatory cytokine · Psychiatry · Psychosocial · Socioeconomic status · Stressor · Clinical Psychology · Health disparities and outcomes · Medicine · Mental Health Research Topics · Stress Responses and Cortisol · Gerontology · Immunology

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Unique citing works12
Citations per year0,8
Citation span2011 - 2025 (15)
Citation velocityrecent
Highly citedNo
Citation typesNeutral: 12
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