Erosive Arthritis of the Foot with Characteristic Features of Tophaceous Gout in the Jomon Skeletal Population

Bibliographic Data

ID6135879
AuthorsKoji Inoue (0000-0001-9817-150X, Shiga University of Medical Science), Hukuda, Shinsuke Hukuda (Shiga University of Medical Science), Masashi Nakai (0000-0002-1219-9307, Primate Research Institute, Kyoto University), Kazumichi Katayama (Primate Research Institute, Kyoto University)
Year1998
Volume106
Issue3
Pages221-228
Publication date1998-01-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAnthropological Science (JOURNAL)
Journal identifiersISSN: 0918-7960 • E-ISSN: 1348-8570
PublisherAnthropological Society of Nippon (PUBLISHER • JP)
DOI10.1537/ase.106.221
OpenAlexW2090219149
LanguageEN
Citations received1
References cited2

We describe the oldest evidence of gout from skeletal remains found in Asia. A middle-aged male skeleton excavated from the shell mound at Ohta in Onomichi-city, Hiroshima prefecture, Western Japan (the middle Jomon period: 4500-3500 BP), showed erosive arthritis in the forefoot. The characteristic feature of the erosions observed in the present skeleton is a periosteal bone apposition at the outer aspect of the involved cortex and a “punched-out” configuration as seen in radiographs. In addition to thesepaleopathological indings, a pauciarticular nature, involvement of the forefoot, male gender and a lack of perilesional osteopenia provided further support for the diagnosis of tophaceous gout. Because gout is associated with good nutrition, the presence of some well-nourished society in Jomon period should be considered

Bone mineral · Facial skeleton · Foot (prosody · Gout · Impaction · Osteopenia · Osteoporosis · Paleopathology · Pathology · Skeleton (computer programming · Dentistry · Gout, Hyperuricemia, Uric Acid · Medicine · Restraint-Related Deaths · Winter Sports Injuries and Performance · Anatomy · Dermatology · Internal Medicine · Orthodontics