Inferring chronological age from DNA methylation patterns of human teeth

Bibliographic Data

ID8312338
AuthorsAlvaro Campuzano Arteta, Cristina Giuliani (0000-0001-6589-1690, Department of Biological, Geological and Environmental Sciences, Laboratory of Molecular Anthropology & Centre for Genome Biology University of Bologna Bologna 40126 Italy), Elisabetta Cilli (0000-0003-0407-267X, Department of Cultural Heritage (DBC), Laboratories of Physical Anthropology and Ancient DNA University of Bologna Ravenna 48121 Italy), Diana Fuentes (0000-0002-9943-6140, Universidad Nacional Autonoma de Mexico), Valeria Coronel (0000-0001-7984-051X, Facultad Latinoamericana de Ciencias Ecuador), Maria Giulia Bacalini (0000-0003-1618-2673, Department of Experimental, Diagnostic and Specialty Medicine (DIMES) University of Bologna Bologna 40126 Italy), Chiara Pirazzini (0000-0001-8248-0295, Department of Experimental, Diagnostic and Specialty Medicine (DIMES) University of Bologna Bologna 40126 Italy), Marco Sazzini (0000-0001-5382-7827, Department of Biological, Geological and Environmental Sciences, Laboratory of Molecular Anthropology & Centre for Genome Biology University of Bologna Bologna 40126 Italy), Giorgio Gruppioni (Department of Cultural Heritage (DBC), Laboratories of Physical Anthropology and Ancient DNA University of Bologna Ravenna 48121 Italy), Claudio Franceschi (0000-0001-9841-6386, Department of Experimental, Diagnostic and Specialty Medicine (DIMES) University of Bologna Bologna 40126 Italy), Paolo Garagnani (0000-0002-4161-3626, Department of Experimental, Diagnostic and Specialty Medicine (DIMES) University of Bologna Bologna 40126 Italy), Donata Luiselli (0000-0003-2105-2478, Department of Biological, Geological and Environmental Sciences, Laboratory of Molecular Anthropology & Centre for Genome Biology University of Bologna Bologna 40126 Italy)
Year2016
Volume159
Issue4
Pages585-595
Publication date2016-04-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAmerican Journal of Physical Anthropology (JOURNAL)
Journal identifiersISSN: 0002-9483 • E-ISSN: 1096-8644
PublisherWiley (PUBLISHER • GB)
DOI10.1002/ajpa.22921
OpenAlexW26667772
LanguageEN
Citations received3
References cited52

We propose for the first time the evaluation of DNA methylation at ELOVL2, FHL2, and PENK genes as a powerful tool to predict age in modern teeth for anthropological applications. Future studies are needed to apply this method also to historical and relatively ancient human teeth

Humanities · Cultural and political discourse analysis · History and Politics in Latin America · Philosophy · Political Theory and Democracy