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Brief communication

Minimally invasive bone sampling method for DNA analysis

Bibliographic Data

ID8317056
AuthorsV E Gibbons (0000-0001-7875-3297, University of the Witwatersrand, corresponding author), Victoria E Gibbon, Clem B Penny, Clem Penny (University of the Witwatersrand), Goran Strkalj (0000-0003-0973-0707, Macquarie University), Paul Ruff (0000-0003-1055-1730, University of the Witwatersrand)
Year2009
Volume139
Issue4
Pages596-599
Publication date2009-08-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAmerican Journal of Physical Anthropology (JOURNAL)
Journal identifiersISSN: 0002-9483 • E-ISSN: 1096-8644
PublisherWiley (PUBLISHER • GB)
DOI10.1002/ajpa.21048
PMID19350643
OpenAlexW2072507577
LanguageEN
Citations received1
References cited22

Obtaining a bone sample for DNA analysis has traditionally been a destructive practice, which has resulted in reluctance on behalf of curators for skeletal collections to allow invasive testing. A novel minimally invasive bone sampling method for DNA analysis is presented here. This method uses a conventional hand drill wherein the bone sample is extracted from the intercondylar fossa of the femur; it does not interfere with any known anthropometric landmarks and only leaves a small hole on the surface of the bone. The temperature of the drill is documented and it was established due to the minor increase in temperature, that this should not affect the molecular integrity of the sample. This method is easily replicated and is suitable for both human and other animal skeletal material and can be applied to rare specimens with little risk. Am J Phys Anthropol, 2009. © 2009 Wiley‐Liss, Inc

Chromatography · Computer vision · Drill · Femur · Sample (material) · Sampling (signal processing) · Biomedical Engineering · Chemistry · Computer Science · Dentistry · Forensic and Genetic Research · Forensic Anthropology and Bioarchaeology Studies · Materials Science · Medicine · Molecular Biology Techniques and Applications · Surgery

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    Open Access•Cristian Marcelo Crespo, M G Russo et al.•Revista Argentina de Antropología…•2016

  • Bone Preservation and Ancient DNA

    Open Access•Susan R Haynes, Susan Haynes et al.•Journal of Archaeological Science•2002

  • Determining the Sex of Infanticide Victims from the Late Roman Era through Ancient DNA Analysis

    Open Access•Marina Faerman, Gila Kahila Bar‐gal et al.•Journal of Archaeological Science•1998

  • Ancient DNA in anthropology

    Open Access•Frederika A Kaestle, K Ann Horsburgh•American Journal of Physical…•2002

  • Investigation of the link between visceral surface rib lesions and tuberculosis in a Medieval skeletal series from England using ancient DNA

    Open Access•S Mays, Edward Fysh et al.•American Journal of Physical…•2002

  • Molecular evidence for different stages of tuberculosis in ancient bone samples from Hungary

    Open Access•Christian J Haas, Albert Zink et al.•American Journal of Physical…•2000

  • Ancient DNA Studies in Physical Anthropology

    Dennis H O''Rourke, Dennis H O'Rourke et al.•Annual Review of Anthropology•2000

  • Comparison of various decalcificators in preparation of DNA from human rib bones

    Open Access•Magdalena Żołędziewska, Stanisław Gronkiewicz et al.•Anthropological Review•2002

Unique citing works1
Citations per year0,1
Citation span2016 - 2016 (1)
Citation velocityhistorical
Highly citedNo
Citation typesNeutral: 1
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