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Bone microarchitecture at muscle attachment sites

The relationship between macroscopic scores of entheses and their cortical and trabecular microstructural design

Bibliographic Data

ID8317994
AuthorsKsenija Djukić (0000-0001-7637-4357, Laboratory for Anthropology Institute of Anatomy Faculty of Medicine University of Belgrade Belgrade Serbia), Petar Milovanović (0000-0003-1461-8437, Laboratory for Anthropology Institute of Anatomy Faculty of Medicine University of Belgrade Belgrade Serbia), Michael Hahn (0000-0002-7022-3918, Department of Osteology & Biomechanics University Medical Center Hamburg‐Eppendorf Hamburg Germany), Björn Busse (0000-0002-3099-8073, Department of Osteology & Biomechanics University Medical Center Hamburg‐Eppendorf Hamburg Germany), Michael Amling (0000-0003-2382-8348, Department of Osteology & Biomechanics University Medical Center Hamburg‐Eppendorf Hamburg Germany), Marija Djurić (0000-0001-6267-827X, Laboratory for Anthropology Institute of Anatomy Faculty of Medicine University of Belgrade Belgrade Serbia, corresponding author)
Year2015
Volume157
Issue1
Pages81-93
Publication date2015-05-01
Peer ReviewedYes
Open AccessYes
TypeARTICLE
VenueAmerican Journal of Physical Anthropology (JOURNAL)
Journal identifiersISSN: 0002-9483 • E-ISSN: 1096-8644
PublisherWiley (PUBLISHER • GB)
DOI10.1002/ajpa.22691
PMID25546406
OpenAlexW2139621886
LanguageEN
Citations received16
References cited56

The studies of entheses in bioarchaeology attempted to reconstruct the habitual physical activities of past populations. However, the studies of microarchitecture of the underlying bone are still lacking despite well‐known potential of bone internal microarchitecture to reflect mechanical loading. It is unknown whether different morphological expressions of entheseal changes (ECs) correlate with the microstructural characteristics of the underlining bone. This study analyzed bone microstructural characteristics at the entheses. Our focus was on examining the possible successive nature of the three‐stage scale of entheseal macroscopic changes by comparing EC scores with the microarchitectural features at the attachment sites. The study was based on the hypothesis that mechanical loading influences the microarchitecture of the bone at the attachment site. The bone samples were taken from 24 adult male skeletons from medieval cemeteries in Serbia, with different macroscopic expression score of EC. We evaluated the macroscopic and microscopic appearance of four entheses of the lower limbs (origin of the soleus muscle and the insertions of the adductor magnus, gluteus maximus, and iliopsoas muscles). The specimens were scanned using microcomputed tomography (Scanco μCT 40). Our data showed a lack of consistent correlation between stages of the macroscopic scoring systems with microarchitecture at the entheses, only cortical thickness was significantly different between EC stages. Analyzing relationship between trabecular and cortical bone microstructure we found correlations between cortical and trabecular variables only in Stage C. Results of our study suggest that macroscopic EC might not represent distinct successive phases in bone adaptation to mechanical loading. Am J Phys Anthropol 157:81–93, 2015. © 2014 Wiley Periodicals, Inc

Biology · Cortical bone · Enthesis · Microarchitecture · Osteoporosis · Pathology · Radiology · Tendon · Trabecular bone · X-ray microtomography · Anatomy · Bone health and osteoporosis research · Computer Science · Lower Extremity Biomechanics and Pathologies · Medicine · Sports injuries and prevention

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Unique citing works16
Citations per year1,6
Citation span2016 - 2026 (11)
Citation velocitycurrent
Highly citedNo
Citation typesNeutral: 15
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