On the problem of immunological detection of antigens in skeletal remains
Bibliographic Data
| ID | 8320142 |
|---|---|
| Authors | Eugenio Lendaro (Sapienza University of Rome), Rodolfo Ippoliti (0000-0003-0652-3470), Andrea Bellelli (0000-0003-0431-6048), Maurizio Brunori (0000-0002-7795-1635), Romano Zito, Gennaro Citro, Antonio Ascenzi (Sapienza University of Rome) |
| Year | 1991 |
| Volume | 86 |
| Issue | 3 |
| Pages | 429-432 |
| Publication date | 1991-11-01 |
| Peer Reviewed | Yes |
| Open Access | Yes |
| Type | ARTICLE |
| Venue | American Journal of Physical Anthropology (JOURNAL) |
| Journal identifiers | ISSN: 0002-9483 • E-ISSN: 1096-8644 |
| Publisher | Wiley (PUBLISHER • GB) |
| DOI | 10.1002/ajpa.1330860308 |
| PMID | 1746647 |
| OpenAlex | W2041286830 |
| Language | EN |
| Citations received | 1 |
| References cited | 6 |
A detailed investigation with affinity‐chromatography‐purified fractions of antihemoglobin serum from rabbit shows that the hemoglobin content of human bones dating back 15 to 3,000 years may be very small. Some of the previous results (Ascenzi et al., 1985) indicating a high hemoglobin titer were vitiated because of an unexpected cross‐reactivity of bone extracts with the hemoglobin‐unreactive fraction of the antiserum. This study calls attention to possible artifacts intrinsic to the application of immunological techniques to the study of archaeological samples
Antibody · Antigen · Antiserum · Biology · Chromatography · Cross reactions · Cross-reactivity · Fraction (chemistry) · Hemoglobin · Titer · Biochemistry · Chemistry · Forensic and Genetic Research · Forensic Anthropology and Bioarchaeology Studies · Forensic Toxicology and Drug Analysis · Immunology
| Unique citing works | 1 |
|---|---|
| Citations per year | 0,17 |
| Citation span | 2020 - 2020 (1) |
| Citation velocity | historical |
| Highly cited | No |
| Citation types | Neutral: 1 |