Giovanni Destro‐bisol
Datos Biográficos
| ID | 100913 |
|---|---|
| NOMBRE | Giovanni Destro‐bisol |
| NOMBRES | Giovanni |
| APELLIDO | Destro‐bisol |
| FIRMA | BISOL G D |
| AFILIACIONES | Department of Animal and Human Biology, University of Rome “La Sapienza,” 00185 Rome, Italy |
| VERIFICADO | No |
| TOTAL DE OBRAS | 11 |
| TOTAL DE CITAS | 14 |
| TOTAL COMO AUTOR | 11 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 1989 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2008 |
| ÍNDICE H | 3 |
Tracing the distribution and evolution of lactase persistence in Southern Europe through the study of the T ‐13910 variant
We investigated the occurrence and intra‐allelic variability of the T ‐13910 variant located upstream of the lactase gene in 965 individuals from 20 different locations of Italy and Greece. The T ‐13910 frequency ranges from 0.072 (Sardinia) to 0.237 (North‐East Italy), with a statistically significant difference between North‐East Italians and other Italian populations. The comparison of the lactose tolerance predicted by T ‐13910 and that asses…
Human Microevolution and the Atlantic Slave Trade
Populations derived from the Atlantic slaving process provide unique opportunities for studying key evolutionary determinants of current patterns of human cultural and biological variation. Examination of the genetic patterning of the small plantation island of São Tomé (Gulf of Guinea) using a study design that avoids the use of preconceived ethno-linguistic labels to define genetic sampling units reveals that, despite the fact that maximum dist…
Brief communication
The hypervariable region‐1 and four nucleotide positions (10400, 10873, 12308, and 12705) of the coding region of mitochondrial DNA (mtDNA) were analyzed in 441 individuals belonging to eight populations (Daba, Fali, Fulbe, Mandara, Uldeme, Podokwo, Tali, and Tupuri) from North Cameroon and four populations (Bakaka, Bassa, Bamileke, and Ewondo) from South Cameroon. All mtDNAs were assigned to five haplogroups: three sub‐Saharan (L1, L2, and L3), …
Binary and microsatellite polymorphisms of the Y‐chromosome in the Mbenzele Pygmies from the Central African Republic
Binary and microsatellite polymorphisms of the Y‐chromosome in the Mbenzele pygmies from the Central African Republic
This study analyzes the variation of six binary polymorphisms and six microsatellites in the Mbenzele Pygmies from the Central African Republic. Five different haplogroups (B2b, E(xE3a), E3a, P and BR(xB2b,DE,P)) were observed, with frequencies ranging from 0.022 (haplogroup P) to 0.609 (haplogroup E3a). A comparison of haplogroup frequencies indicates a close genetic affinity between the Mbenzele and the Biaka Pygmies, a finding consistent with …
Variation at 10 protein coding loci in the mbenzele pygmies from the central african republic and a comparison with microsatellite data
Ten protein coding loci (6-PGD, A1-AT, ACP1, CaII, ESD, GC, GPX1, Hb beta, PGM1, and TF) were analyzed in the Mbenzele Pygmies from the Central African Republic. The frequency data were used to calculate the genetic distances between Mbenzele Pygmies and other African groups. In the principal coordinate plot of FST genetic distances, the Mbenzele cluster together with other Pygmies of the western cluster, the Biaka from C.A.R., Gielli from Camero…
Biological and cultural contradictions? A reply to MacEachern
In his comment appearing in this issue of the AmericanJournal of Physical Anthropology, MacEachern(2001) questions some conclusions drawn in our longtermsurvey of genetic variation in Cameroon (Spediniet al., 1999). In our reply, we would like toclarify certain points so as to put AJPA readers in aposition whereby they understand both viewpoints
Resistance to Falciparum malaria in α‐thalassemia, oxidative stress, and hemoglobin oxidation
A recent survey conducted on Vanuatu Island suggests that resistance to Plasmodium falciparum in alpha-thalassemic individuals may have an immunological basis. This study is important since it seems to undermine the current idea that red-cell genetic defects give protection against falciparum malaria by reducing intraerythrocytic growth and development of the parasite. However, the mechanisms underlying these clinical and genetic observations are…
Resistance to Falciparum malaria in α-thalassemia, oxidative stress, and hemoglobin oxidation
A recent survey conducted on Vanuatu Island suggests that resistance to Plasmodium falciparum in α-thalassemic individuals may have an immunological basis. This study is important since it seems to undermine the current idea that red-cell genetic defects give protection against falciparum malaria by reducing intraerythrocytic growth and development of the parasite. However, the mechanisms underlying these clinical and genetic observations are not…
Interaction between oxidized hemoglobin and the cell membrane
Anthropological survey on red cell glutathione peroxidase (GPX1) polymorphism in Central Western Africa
Phenotype and allele frequencies for erythrocyte glutathione peroxidase (GPX1) polymorphism are reported in the Mbugu and Sango (Central African Republic), Goun (Benin), and Bamileke (Cameroon) ethnic groups. The GPX1*2 allele frequencies (from 0.012 in the Sango to 0.058 in the Bamileke) fit into the range of the data already known for the Subsaharan populations. The value of GPX1*2 for study of the genetic admixture between Negro and Pygmy popu…
Brief communication
The hypervariable region‐1 and four nucleotide positions (10400, 10873, 12308, and 12705) of the coding region of mitochondrial DNA (mtDNA) were analyzed in 441 individuals belonging to eight populations (Daba, Fali, Fulbe, Mandara, Uldeme, Podokwo, Tali, and Tupuri) from North Cameroon and four populations (Bakaka, Bassa, Bamileke, and Ewondo) from South Cameroon. All mtDNAs were assigned to five haplogroups: three sub‐Saharan (L1, L2, and L3), …
Human Microevolution and the Atlantic Slave Trade
Populations derived from the Atlantic slaving process provide unique opportunities for studying key evolutionary determinants of current patterns of human cultural and biological variation. Examination of the genetic patterning of the small plantation island of São Tomé (Gulf of Guinea) using a study design that avoids the use of preconceived ethno-linguistic labels to define genetic sampling units reveals that, despite the fact that maximum dist…
Biological and cultural contradictions? A reply to MacEachern
In his comment appearing in this issue of the AmericanJournal of Physical Anthropology, MacEachern(2001) questions some conclusions drawn in our longtermsurvey of genetic variation in Cameroon (Spediniet al., 1999). In our reply, we would like toclarify certain points so as to put AJPA readers in aposition whereby they understand both viewpoints
Anthropological survey on red cell glutathione peroxidase (GPX1) polymorphism in Central Western Africa
Phenotype and allele frequencies for erythrocyte glutathione peroxidase (GPX1) polymorphism are reported in the Mbugu and Sango (Central African Republic), Goun (Benin), and Bamileke (Cameroon) ethnic groups. The GPX1*2 allele frequencies (from 0.012 in the Sango to 0.058 in the Bamileke) fit into the range of the data already known for the Subsaharan populations. The value of GPX1*2 for study of the genetic admixture between Negro and Pygmy popu…
Interaction between oxidized hemoglobin and the cell membrane
Resistance to Falciparum malaria in α‐thalassemia, oxidative stress, and hemoglobin oxidation
A recent survey conducted on Vanuatu Island suggests that resistance to Plasmodium falciparum in alpha-thalassemic individuals may have an immunological basis. This study is important since it seems to undermine the current idea that red-cell genetic defects give protection against falciparum malaria by reducing intraerythrocytic growth and development of the parasite. However, the mechanisms underlying these clinical and genetic observations are…
Resistance to Falciparum malaria in α-thalassemia, oxidative stress, and hemoglobin oxidation
A recent survey conducted on Vanuatu Island suggests that resistance to Plasmodium falciparum in α-thalassemic individuals may have an immunological basis. This study is important since it seems to undermine the current idea that red-cell genetic defects give protection against falciparum malaria by reducing intraerythrocytic growth and development of the parasite. However, the mechanisms underlying these clinical and genetic observations are not…
Variation at 10 protein coding loci in the mbenzele pygmies from the central african republic and a comparison with microsatellite data
Ten protein coding loci (6-PGD, A1-AT, ACP1, CaII, ESD, GC, GPX1, Hb beta, PGM1, and TF) were analyzed in the Mbenzele Pygmies from the Central African Republic. The frequency data were used to calculate the genetic distances between Mbenzele Pygmies and other African groups. In the principal coordinate plot of FST genetic distances, the Mbenzele cluster together with other Pygmies of the western cluster, the Biaka from C.A.R., Gielli from Camero…
Biological and cultural contradictions? A reply to MacEachern
In his comment appearing in this issue of the AmericanJournal of Physical Anthropology, MacEachern(2001) questions some conclusions drawn in our longtermsurvey of genetic variation in Cameroon (Spediniet al., 1999). In our reply, we would like toclarify certain points so as to put AJPA readers in aposition whereby they understand both viewpoints
Binary and microsatellite polymorphisms of the Y‐chromosome in the Mbenzele Pygmies from the Central African Republic
Binary and microsatellite polymorphisms of the Y‐chromosome in the Mbenzele pygmies from the Central African Republic
This study analyzes the variation of six binary polymorphisms and six microsatellites in the Mbenzele Pygmies from the Central African Republic. Five different haplogroups (B2b, E(xE3a), E3a, P and BR(xB2b,DE,P)) were observed, with frequencies ranging from 0.022 (haplogroup P) to 0.609 (haplogroup E3a). A comparison of haplogroup frequencies indicates a close genetic affinity between the Mbenzele and the Biaka Pygmies, a finding consistent with …
Brief communication
The hypervariable region‐1 and four nucleotide positions (10400, 10873, 12308, and 12705) of the coding region of mitochondrial DNA (mtDNA) were analyzed in 441 individuals belonging to eight populations (Daba, Fali, Fulbe, Mandara, Uldeme, Podokwo, Tali, and Tupuri) from North Cameroon and four populations (Bakaka, Bassa, Bamileke, and Ewondo) from South Cameroon. All mtDNAs were assigned to five haplogroups: three sub‐Saharan (L1, L2, and L3), …
Tracing the distribution and evolution of lactase persistence in Southern Europe through the study of the T ‐13910 variant
We investigated the occurrence and intra‐allelic variability of the T ‐13910 variant located upstream of the lactase gene in 965 individuals from 20 different locations of Italy and Greece. The T ‐13910 frequency ranges from 0.072 (Sardinia) to 0.237 (North‐East Italy), with a statistically significant difference between North‐East Italians and other Italian populations. The comparison of the lactose tolerance predicted by T ‐13910 and that asses…
Human Microevolution and the Atlantic Slave Trade
Populations derived from the Atlantic slaving process provide unique opportunities for studying key evolutionary determinants of current patterns of human cultural and biological variation. Examination of the genetic patterning of the small plantation island of São Tomé (Gulf of Guinea) using a study design that avoids the use of preconceived ethno-linguistic labels to define genetic sampling units reveals that, despite the fact that maximum dist…
Biology (11 obras) · Evolutionary biology (7 obras) · Genetics (5 obras) · Allele (4 obras) · Biochemistry (4 obras) · Gene (4 obras) · Genetic diversity and population structure (4 obras) · Genetics (4 obras) · History (4 obras) · Sociology (4 obras)