Euripedes Constantino Miguel
Datos Biográficos
| ID | 130534 |
|---|---|
| NOMBRE | Euripedes Constantino Miguel |
| NOMBRES | Euripedes Constantino |
| APELLIDO | Miguel |
| FIRMA | MIGUEL E C |
| AFILIACIONES | Universidade de São Paulo |
| ORCID | 0000-0002-9393-3103 |
| VERIFICADO | Sí |
| TOTAL DE OBRAS | 18 |
| TOTAL DE CITAS | 1 |
| TOTAL COMO AUTOR | 18 |
| TOTAL COMO EDITOR | 0 |
| PRIMER AÑO DE PUBLICACIÓN | 2018 |
| AÑO MÁS RECIENTE DE PUBLICACIÓN | 2026 |
| ÍNDICE H | 1 |
Acceptability and Feasibility of Internet-Based Cognitive-Behavioral Therapy for Obsessive-Compulsive Disorder in Brazil
Social connection and its prospective association with adolescent internalising and externalising symptoms
BACKGROUND: Social connection factors play a key role for young people's mental health. It is important to understand how their influence may vary across contexts. We investigated structural (e.g. household size), functional (e.g. social support) and quality (e.g. feeling close) social connection factors in relation to adolescent internalising and externalising symptoms, comparing two countries Brazil and the United Kingdom (UK). METHODS: We pool…
A Preliminary Investigation of Associations Between Traumatic Events Experienced During Pregnancy and Salivary Diurnal Cortisol Levels of Brazilian Adolescent Mothers and Infants
INTRODUCTION: Interpersonal violence against women is a major global health problem that may have intergenerational effects. This study investigated associations between maternal experiences of interpersonal violence and other traumatic events and maternal and infant salivary diurnal cortisol in a cohort of adolescent mothers in São Paulo, Brazil. METHOD: Adolescent mothers (14-19 years) participating in a home-visiting intervention were intervie…
Beyond technique
Protocol for a hybrid type I randomized controlled trial evaluating the effectiveness and implementation of a nurse home visiting program for adolescent pregnancy on maternal and infant outcomes
This study will provide evidence on the clinical and practical benefits of nurse home visiting programs for adolescent pregnancy in primary care, guiding their integration, scale-up, and potential adaptation for global maternal and child health initiatives. The findings aim to inform policymakers and healthcare providers on effective strategies to address adolescent pregnancy and improve health outcomes in low-resource settings
Impact of life adversity and gene expression on psychiatric symptoms in children and adolescents
Among these nine genes, NR3C1, which encodes a glucocorticoid receptor, is by far the most investigated, being associated with depressive symptoms, early life adversity, and stress. While further research is needed to fully understand the complex relationship between gene expression, life adversities, and psychopathology, our findings provide valuable insights into the molecular mechanisms underlying mental disorders
Mapping the Relationships between Dimensions of Child Anxiety, Parental Anxiety, and Family Accommodation
Disentangling the influences of parental genetics on offspring's cognition, education, and psychopathology via genetic and phenotypic pathways
BACKGROUND: Specific pathways of intergenerational transmission of behavioral traits remain unclear. Here, we aim to investigate how parental genetics influence offspring cognition, educational attainment, and psychopathology in youth. METHODS: Participants for the discovery sample were 2,189 offspring (aged 6-14 years), 1898 mothers and 1,017 fathers who underwent genotyping, psychiatric, and cognitive assessments. We calculated polygenic scores…
Co-Occurring Obsessive–Compulsive Disorder and Compulsive Sexual Behavior
Association Between Obsessive-Compulsive Symptom Dimensions in Mothers and Psychopathology in Their Children
Background: The non-clinical presentation of obsessive-compulsive symptoms (OCS) in women may impact not only their daily lives and well-being but also increase the risk for emotional and behavioral problems in their children. This study aims to investigate the OCS dimension distribution in a large sample of mothers from a cohort of school age children and the association between these OCS dimensions with their own psychopathology, and with the p…
Lower Ventromedial Prefrontal Cortex Glutamate Levels in Patients With Obsessive–Compulsive Disorder
Background: Recent studies using magnetic resonance spectroscopy ( 1 H-MRS) indicate that patients with obsessive-compulsive disorder (OCD) present abnormal levels of glutamate (Glu) and gamma aminobutyric acid (GABA) in the frontal and striatal regions of the brain. These abnormalities could be related to the hyperactivation observed in cortico-striatal circuits of patients with OCD. However, most of the previous 1 H-MRS studies were not capable…
Development and validation of the Brazilian Portuguese Version of the Reported and Intended Behaviour Scale (Ribs-BP)
The object of the study was to translate and validate the Reported and Intended Behaviour Scale (RIBS) into Brazilian Portuguese. A native Brazilian speaker fluent in English translated the RIBS into Brazilian Portuguese. Comprehensibility and face validity were assessed through discussions with mental health professionals and volunteers recruited from the community. Brazilian Portuguese version of the questionnaire was back-translated into Engli…
Obsessive–Compulsive Personality Symptoms Predict Poorer Response to Gamma Ventral Capsulotomy for Intractable OCD
Gamma ventral capsulotomy (GVC) is a radiosurgical procedure which aims to create lesions in the ventral part of the anterior limb of the internal capsule (ALIC). It has been used as a treatment option for patients with intractable obsessive-compulsive disorder (OCD) who do not respond to several first-line treatments attempts. However, changes in personality disorder symptoms after GVC have not been investigated. The aims of this study are to in…
Level of Insight in Patients With Obsessive–Compulsive Disorder
Introduction: Insight may be defined as the ability to perceive and evaluate external reality and to separate it from its subjective aspects. It also refers to the ability to self-assess difficulties and personal qualities. Insight may be a predictor of success in the treatment of obsessive-compulsive disorder (OCD), so that individuals with poor insight tend to become refractory to treatment. The objective of this study is to investigate factors…
Differences Between Self-Reported Psychotic Experiences, Clinically Relevant Psychotic Experiences, and Attenuated Psychotic Symptoms in the General Population
Purpose: Psychotic experiences in childhood (such as hearing voices or being suspicious) represent an important phenotype for early intervention. However, these experiences can be defined in several ways: self-reported psychotic experiences (SRPE) rely exclusively on the child's report, clinically validated psychotic experiences (CRPE) are based on clinical assessment, and attenuated psychotic symptoms (APS) represents a categorization to do with…
Kundalini Yoga Meditation Versus the Relaxation Response Meditation for Treating Adults With Obsessive-Compulsive Disorder
Background: Obsessive-compulsive disorder (OCD) is often a life-long disorder with high psychosocial impairment. Serotonin reuptake inhibitors (SRIs) are the only FDA approved drugs, and approximately 50% of patients are non-responders when using a criterion of 25% to 35% improvement with the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS). About 30% are non-responders to combined first-line therapies (SRIs and exposure and response prevention). P…
Prevalência de problemas de saúde mental na infância na atenção primária
O presente estudo populacional de corte transversal teve como objetivo verificar a prevalência de problemas de saúde mental (PSM) e descrever o uso de serviços de saúde numa amostra de crianças atendidas em unidades de saúde (UBS) do município de São Paulo. Responsáveis de 825 crianças de 6-11 anos de idade foram entrevistados. PSM das crianças foram avaliados pelo “Strength and Difficulties Questionnaire” e uso de serviços por uma versão adaptad…
Cross-Sectional and Longitudinal Associations of Temperament and Mental Disorders in Youth
Prevalência de problemas de saúde mental na infância na atenção primária
O presente estudo populacional de corte transversal teve como objetivo verificar a prevalência de problemas de saúde mental (PSM) e descrever o uso de serviços de saúde numa amostra de crianças atendidas em unidades de saúde (UBS) do município de São Paulo. Responsáveis de 825 crianças de 6-11 anos de idade foram entrevistados. PSM das crianças foram avaliados pelo “Strength and Difficulties Questionnaire” e uso de serviços por uma versão adaptad…
Cross-Sectional and Longitudinal Associations of Temperament and Mental Disorders in Youth
Level of Insight in Patients With Obsessive–Compulsive Disorder
Introduction: Insight may be defined as the ability to perceive and evaluate external reality and to separate it from its subjective aspects. It also refers to the ability to self-assess difficulties and personal qualities. Insight may be a predictor of success in the treatment of obsessive-compulsive disorder (OCD), so that individuals with poor insight tend to become refractory to treatment. The objective of this study is to investigate factors…
Differences Between Self-Reported Psychotic Experiences, Clinically Relevant Psychotic Experiences, and Attenuated Psychotic Symptoms in the General Population
Purpose: Psychotic experiences in childhood (such as hearing voices or being suspicious) represent an important phenotype for early intervention. However, these experiences can be defined in several ways: self-reported psychotic experiences (SRPE) rely exclusively on the child's report, clinically validated psychotic experiences (CRPE) are based on clinical assessment, and attenuated psychotic symptoms (APS) represents a categorization to do with…
Kundalini Yoga Meditation Versus the Relaxation Response Meditation for Treating Adults With Obsessive-Compulsive Disorder
Background: Obsessive-compulsive disorder (OCD) is often a life-long disorder with high psychosocial impairment. Serotonin reuptake inhibitors (SRIs) are the only FDA approved drugs, and approximately 50% of patients are non-responders when using a criterion of 25% to 35% improvement with the Yale-Brown Obsessive-Compulsive Scale (Y-BOCS). About 30% are non-responders to combined first-line therapies (SRIs and exposure and response prevention). P…
Development and validation of the Brazilian Portuguese Version of the Reported and Intended Behaviour Scale (Ribs-BP)
The object of the study was to translate and validate the Reported and Intended Behaviour Scale (RIBS) into Brazilian Portuguese. A native Brazilian speaker fluent in English translated the RIBS into Brazilian Portuguese. Comprehensibility and face validity were assessed through discussions with mental health professionals and volunteers recruited from the community. Brazilian Portuguese version of the questionnaire was back-translated into Engli…
Obsessive–Compulsive Personality Symptoms Predict Poorer Response to Gamma Ventral Capsulotomy for Intractable OCD
Gamma ventral capsulotomy (GVC) is a radiosurgical procedure which aims to create lesions in the ventral part of the anterior limb of the internal capsule (ALIC). It has been used as a treatment option for patients with intractable obsessive-compulsive disorder (OCD) who do not respond to several first-line treatments attempts. However, changes in personality disorder symptoms after GVC have not been investigated. The aims of this study are to in…
Association Between Obsessive-Compulsive Symptom Dimensions in Mothers and Psychopathology in Their Children
Background: The non-clinical presentation of obsessive-compulsive symptoms (OCS) in women may impact not only their daily lives and well-being but also increase the risk for emotional and behavioral problems in their children. This study aims to investigate the OCS dimension distribution in a large sample of mothers from a cohort of school age children and the association between these OCS dimensions with their own psychopathology, and with the p…
Lower Ventromedial Prefrontal Cortex Glutamate Levels in Patients With Obsessive–Compulsive Disorder
Background: Recent studies using magnetic resonance spectroscopy ( 1 H-MRS) indicate that patients with obsessive-compulsive disorder (OCD) present abnormal levels of glutamate (Glu) and gamma aminobutyric acid (GABA) in the frontal and striatal regions of the brain. These abnormalities could be related to the hyperactivation observed in cortico-striatal circuits of patients with OCD. However, most of the previous 1 H-MRS studies were not capable…
Co-Occurring Obsessive–Compulsive Disorder and Compulsive Sexual Behavior
Disentangling the influences of parental genetics on offspring's cognition, education, and psychopathology via genetic and phenotypic pathways
BACKGROUND: Specific pathways of intergenerational transmission of behavioral traits remain unclear. Here, we aim to investigate how parental genetics influence offspring cognition, educational attainment, and psychopathology in youth. METHODS: Participants for the discovery sample were 2,189 offspring (aged 6-14 years), 1898 mothers and 1,017 fathers who underwent genotyping, psychiatric, and cognitive assessments. We calculated polygenic scores…
Social connection and its prospective association with adolescent internalising and externalising symptoms
BACKGROUND: Social connection factors play a key role for young people's mental health. It is important to understand how their influence may vary across contexts. We investigated structural (e.g. household size), functional (e.g. social support) and quality (e.g. feeling close) social connection factors in relation to adolescent internalising and externalising symptoms, comparing two countries Brazil and the United Kingdom (UK). METHODS: We pool…
A Preliminary Investigation of Associations Between Traumatic Events Experienced During Pregnancy and Salivary Diurnal Cortisol Levels of Brazilian Adolescent Mothers and Infants
INTRODUCTION: Interpersonal violence against women is a major global health problem that may have intergenerational effects. This study investigated associations between maternal experiences of interpersonal violence and other traumatic events and maternal and infant salivary diurnal cortisol in a cohort of adolescent mothers in São Paulo, Brazil. METHOD: Adolescent mothers (14-19 years) participating in a home-visiting intervention were intervie…
Beyond technique
Protocol for a hybrid type I randomized controlled trial evaluating the effectiveness and implementation of a nurse home visiting program for adolescent pregnancy on maternal and infant outcomes
This study will provide evidence on the clinical and practical benefits of nurse home visiting programs for adolescent pregnancy in primary care, guiding their integration, scale-up, and potential adaptation for global maternal and child health initiatives. The findings aim to inform policymakers and healthcare providers on effective strategies to address adolescent pregnancy and improve health outcomes in low-resource settings
Impact of life adversity and gene expression on psychiatric symptoms in children and adolescents
Among these nine genes, NR3C1, which encodes a glucocorticoid receptor, is by far the most investigated, being associated with depressive symptoms, early life adversity, and stress. While further research is needed to fully understand the complex relationship between gene expression, life adversities, and psychopathology, our findings provide valuable insights into the molecular mechanisms underlying mental disorders
Mapping the Relationships between Dimensions of Child Anxiety, Parental Anxiety, and Family Accommodation
Acceptability and Feasibility of Internet-Based Cognitive-Behavioral Therapy for Obsessive-Compulsive Disorder in Brazil
Psychology (17 obras) · Medicine (14 obras) · Psychiatry (13 obras) · Clinical Psychology (12 obras) · Clinical Psychology (9 obras) · Internal Medicine (7 obras) · Obsessive-Compulsive Spectrum Disorders (7 obras) · Child and Adolescent Psychosocial and Emotional Development (6 obras) · Anxiety (4 obras) · Cohort (4 obras)